Search Results - "Hawthorne, Danielle"
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Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition
Published in Journal of neuroinflammation (14-08-2020)“…Triggering receptor expressed on myeloid cell-2 (TREM2) is a lipid and lipoprotein binding receptor expressed by cells of myeloid origin. Homozygous TREM2…”
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Time course of neuropathological events in hyperhomocysteinemic amyloid depositing mice reveals early neuroinflammatory changes that precede amyloid changes and cerebrovascular events
Published in Journal of neuroinflammation (30-12-2019)“…Vascular contributions to cognitive impairment and dementia (VCID) are the second leading cause of dementia behind only Alzheimer's disease (AD); however, VCID…”
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Glial changes are associated with cerebrovascular integrity in hyperhomocysteinemia‐induced VCID in mouse and human brain
Published in Alzheimer's & dementia (01-12-2023)“…Background With the aged population estimated to double by 2050 and the rate of dementia expected to triple, it is critical to identify treatments for…”
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Hyperhomocysteinemia as a model of VCID: Development of new models and analysis methods/behavioral models
Published in Alzheimer's & dementia (01-12-2020)Get full text
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Hyperhomocysteinemia as a model of VCID
Published in Alzheimer's & dementia (01-12-2020)“…Background Vascular contributions to cognitive impairment and dementia (VCID) are increasingly recognized as a significant cause of dementia. Furthermore, VCID…”
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Time course of neuropathologic changes in hyperhomocysteinemia‐induced VCID
Published in Alzheimer's & dementia (01-12-2021)“…Background Vascular contributions to cognitive impairment and dementia (VCID) have been increasingly recognized as a leading cause of dementia along with…”
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Elucidating the neurodegnerative sequelae leading to VCID pathology
Published in Alzheimer's & dementia (01-12-2021)“…Background Vascular contributions to cognitive impairment and dementia (VCID) are one of the leading causes of dementia. High levels of plasma homocysteine or…”
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Public Mental Health Clients with Severe Mental Illness and Probable Posttraumatic Stress Disorder: Trauma Exposure and Correlates of Symptom Severity
Published in Journal of traumatic stress (01-04-2013)“…Individuals with severe mental illness (SMI) are at greatly increased risk for trauma exposure and for the development of posttraumatic stress disorder (PTSD)…”
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Investigating the effects of homocysteine as an agonist on invertebrate glutamatergic synapses
Published in Impulse (Columbia, S.C.) (01-07-2018)“…Hyperhomocysteinemia (HHcy) in mammals can produce neurological deficits, such as memory loss. The cause of the neurological issues is assumed to be due to…”
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Effects of clove oil (eugenol) on proprioceptive neurons, heart rate, and behavior in model crustaceans
Published in Impulse (Columbia, S.C.) (01-06-2018)“…Clove oil contains eugenol as an active ingredient and is used as a topical anesthetic in mammals to remedy pain and to anesthetize fish and other seafood for…”
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A comparative study of the MATRICS and IntegNeuro cognitive assessment batteries
Published in Journal of clinical and experimental neuropsychology (01-01-2010)“…Cognitive impairment is prevalent in schizophrenia and is related to poorer functional and treatment outcomes. Cognitive assessment is therefore now a routine…”
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An effectiveness study of the UCLA Friendship and Intimacy module
Published 01-01-2013“…The sexual and relationship needs of individuals diagnosed with serious and persistent mental illness (SPMI) are often ignored by psychiatric treatment…”
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Dissertation