Search Results - "Haws, L.C"

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    Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development by Chappell, G.A., Heintz, M.M., Haws, L.C.

    Published in Current research in toxicology (01-01-2021)
    “…[Display omitted] •Minimal global gene expression changes at concentrations below 600 ppm of 1,4-dioxane.•Increased phase II metabolism genes and cellular…”
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    Journal Article
  3. 3

    Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium by Kirman, C.R., Hays, S.M., Aylward, L.L., Suh, M., Harris, M.A., Thompson, C.M., Haws, L.C., Proctor, D.M.

    Published in Chemico-biological interactions (25-10-2012)
    “…► A PBPK model was developed for oral Cr in rodents that includes the GI tract. ► Target tissue Cr data were collected in rodents exposed to Cr(VI) for 90days…”
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  4. 4

    Physiologically based pharmacokinetic model for humans orally exposed to chromium by Kirman, C.R., Aylward, L.L., Suh, M., Harris, M.A., Thompson, C.M., Haws, L.C., Proctor, D.M., Lin, S.S., Parker, W., Hays, S.M.

    Published in Chemico-biological interactions (25-06-2013)
    “…•Human gastric fluid samples were collected to measure Cr(VI) reduction.•Cr(VI) reduction is pH-dependent, mixed second order, and capacity limited.•A human…”
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    Assessment of human health risks posed by consumption of fish from the Lower Passaic River, New Jersey by Urban, J.D., Tachovsky, J.A., Haws, L.C., Wikoff Staskal, D., Harris, M.A.

    Published in The Science of the total environment (20-12-2009)
    “…The Lower Passaic River (LPR) in New Jersey has been impacted by variety of human activities over the course of the last two centuries. In this risk…”
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  6. 6

    Comparison of Blood Lead Concentrations in U.S. Children by Age, Race/Ethnicity, and Income by Harris, M, Scott, L.L.F, Nguyen, L.M, Haws, L.C

    Published in Annals of epidemiology (2007)
    “…Purpose To evaluate changes in associations between demographic factors and elevated BLLs in children, we determined the percentage of children 1–5 years of…”
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  7. 7

    Factors Contributing to Blood Lead Levels of U.S. Children by Nguyen, L.M, Scott, L.L.F, Harris, M, Haws, L.C

    Published in Annals of epidemiology (2007)
    “…Purpose While elemental lead has been removed from a variety of products over the past 30 years, it is still a widely distributed metal in the environment and…”
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  8. 8

    Assessment of Potential Human Health Risks Posed by Benzene in Beverages by Haws, L.C, Tachovsky, J.A, Williams, E.S, Scott, L.L.F, Paustenbach, D.J, Harris, M.A

    Published in Journal of food science (01-05-2008)
    “…A recent study by the U.S. Food and Drug Administration (FDA) indicated that some beverages contained benzene at levels above the federal drinking water…”
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  9. 9

    Effects of Excluding Serum PCDD/F and Dioxin-Like PCB Data of Individuals with Incomplete Congener Profiles on Estimates of Total TEQ by Scott, L.L.F, Harris, M, Unice, K.M, Scott, P, Nguyen, L.M, Haws, L.C, Paustenbach, D

    Published in Annals of epidemiology (01-09-2007)
    “…Purpose We assessed whether excluding individuals without complete congener profiles biased various total TCDD TEQ estimates calculated using both the WHO1998…”
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  10. 10

    Referent Concentrations of PCDD/Fs and Dioxin-Like PCBs in Sera of Persons in the U.S. Based on the New Who 2006 TEFs and 2001–2002 NHANES Data by Pastenbach, D.J, Scott, L.L.F, Nguyen, L.M, Unice, K.M, Scott, P, Haws, L.C, Harris, M

    Published in Annals of epidemiology (01-09-2007)
    “…Purpose Reference values for PCDD/Fs and dioxin-like PCBs in serum were recently published based on the WHO1998 TEFs and NHANES data. In 2006, the World Health…”
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    Evaluation of impact of shale gas operations in the Barnett Shale region on volatile organic compounds in air and potential human health risks by Bunch, A.G., Perry, C.S., Abraham, L., Wikoff, D.S., Tachovsky, J.A., Hixon, J.G., Urban, J.D., Harris, M.A., Haws, L.C.

    Published in The Science of the total environment (15-01-2014)
    “…Shale gas exploration and production (E&P) has experienced substantial growth across the U.S. over the last decade. The Barnett Shale, in north-central Texas,…”
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  12. 12

    Systematic update to the mammalian relative potency estimate database and development of best estimate toxic equivalency factors for dioxin-like compounds by Fitch, S., Blanchette, A., Haws, L.C., Franke, K., Ring, C., DeVito, M., Wheeler, M., Walker, N., Birnbaum, L., Van Ede, K.I., Antunes Fernandes, E.C., Wikoff, D.S.

    Published in Regulatory toxicology and pharmacology (01-02-2024)
    “…The World Health Organization (WHO) assesses potential health risks of dioxin-like compounds using Toxic Equivalency Factors (TEFs). This study systematically…”
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  13. 13

    A high dose mode of action for tetrabromobisphenol A-induced uterine adenocarcinomas in Wistar Han rats: A critical evaluation of key events in an adverse outcome pathway framework by Wikoff, D.S., Rager, J.E., Haws, L.C., Borghoff, S.J.

    Published in Regulatory toxicology and pharmacology (01-06-2016)
    “…TBBPA is a non-genotoxic flame retardant used to improve fire safety in a wide variety of consumer products. Estimated human exposures to TBBPA are very low…”
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    Risk of Gastrointestinal Disease Associated with Exposure to Pathogens in the Sediments of the Lower Passaic River by Donovan, E.P, Staskal, D.F, Unice, K.M, Roberts, J.D, Haws, L.C, Finley, B.L, Harris, M.A

    Published in Applied and Environmental Microbiology (01-02-2008)
    “…High levels of pathogenic microorganisms have been documented previously in waters of the Lower Passaic River in northern New Jersey. The purpose of this study…”
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  17. 17

    Reduction of a large fish tissue analyte database: Identifying and assessing data specific to a remediation site for risk assessment application by Tachovsky, J.A., Urban, J.D., Wikoff, D. Staskal, Haws, L.C., Harris, M.A.

    Published in Chemosphere (Oxford) (01-07-2010)
    “…The Lower Passaic River (LPR) is one of the most heavily industrialized waterways in the US with both historical and continuing discharges of chemicals from…”
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    Generally recognized as safe (GRAS) evaluation of 4-hexylresorcinol for use as a processing aid for prevention of melanosis in shrimp by Frankos, V H, Schmitt, D F, Haws, L C, McEvily, A J, Iyengar, R, Miller, S A, Munro, I C, Clydesdale, F M, Forbes, A L, Sauer, R M

    Published in Regulatory toxicology and pharmacology (01-10-1991)
    “…4-Hexylresorcinol (C12H18O2) is proposed for use as a processing aid for prevention of melanosis ("black spot") in shrimp and as an alternative to the…”
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    Two approaches for assessing human safety of disperse blue 1 by Haws, L C, Jackson, B A, Turnbull, D, Dressler, W E

    Published in Regulatory toxicology and pharmacology (01-02-1994)
    “…Disperse Blue 1 is an anthraquinone dye used at low levels in semipermanent hair color formulations. Dietary administration of Disperse Blue 1 in a National…”
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