Search Results - "Hawrylik, Steven J"

Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase by Butler, Christopher R., Beck, Elizabeth M., Harris, Anthony, Huang, Zhen, McAllister, Laura A., am Ende, Christopher W., Fennell, Kimberly, Foley, Timothy L., Fonseca, Kari, Hawrylik, Steven J., Johnson, Douglas S., Knafels, John D., Mente, Scot, Noell, G. Stephen, Pandit, Jayvardhan, Phillips, Tracy B., Piro, Justin R., Rogers, Bruce N., Samad, Tarek A., Wang, Jane, Wan, Shuangyi, Brodney, Michael A.

“…Monoacylglycerol lipase (MAGL) is the main enzyme responsible for degradation of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the CNS. MAGL catalyzes…”
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Glycomimetic Ligands for the Human Asialoglycoprotein Receptor by Mamidyala, Sreeman K, Dutta, Sanjay, Chrunyk, Boris A, Préville, Cathy, Wang, Hong, Withka, Jane M, McColl, Alexander, Subashi, Timothy A, Hawrylik, Steven J, Griffor, Matthew C, Kim, Sung, Pfefferkorn, Jeffrey A, Price, David A, Menhaji-Klotz, Elnaz, Mascitti, Vincent, Finn, M.G

“…The asialoglycoprotein receptor (ASGPR) is a high-capacity galactose-binding receptor expressed on hepatocytes that binds its native substrates with low…”
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Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules by Thompson, John F, Wang, Ing-Kae, Stutzman-Engwall, Kim J, Freeman, Thomas B, Chrunyk, Boris A, Hayward, Cheryl M, Ammirati, Mark J, Cong, Yang, Lloyd, David B, Subashi, Timothy A, Karam, George A, Hoth, Lise R, McGrath, Katherine M, Seddon, Andrew P, Lira, Maruja E, Mistry, Anil, Hawrylik, Steven J, Qiu, Xiayang, Geoghegan, Kieran F, Griffor, Matthew C, Hensley, Preston, Clark, Ronald W, Danley, Dennis E, Subashi, Ann K, Zhao, Honglei, Culp, Jeffrey S

“…Cholesteryl ester transfer protein (CETP) shuttles various lipids between lipoproteins, resulting in the net transfer of cholesteryl esters from…”
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X-ray analysis of HIV-1 proteinase at 2.7 resolution confirms structural homology among retroviral enzymes by Lapatto, Risto, Blundell, Tom, Hemmings, Andrew, Overington, John, Wilderspin, Andrew, Wood, Stephen, Merson, James R, Whittle, Peter J, Danley, Dennis E, Geoghegan, Kieran F, Hawrylik, Steven J, Lee, S. Edward, Scheld, Kathryn G, Hobart, Peter M

“…Knowledge of the tertiary structure of the proteinase from human immunodeficiency virus HIV-1 is important to the design of inhibitors that might possess…”
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Purification and Characterization of a Unique Alkaline Elastase from Micrococcus luteus by Clark, Deborah J, Hawrylik, Steven J, Kavanagh, Edward, Opheim, Dennis J

“…Micrococcus luteus isolated from human skin secretes an alkaline protease which degrades elastin. M. luteus protease (MLP) was produced in the late logarithmic…”
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Production and characterization of guinea pig IL-5 in baculovirus-infected insect cells by Mansour, M, Karmilowicz, M, Hawrylik, S J, Nalcerio, B, Angilly, J, Conklyn, M J, Lilly, C M, Drazen, J M, Lee, S E, Auperin, D D, De Wet, J R, Cohan, V L, Showell, H J, Danley, D E

“…To study the role interleukin (IL)-5 may play in altering airway function in asthma, we have produced recombinant protein for exogenous administration to…”
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Isolation, purification and characterization of an extracellular alkaline protease of Micrococcus luteus by Hawrylik, Steven J

“…An extracellular alkaline proteolytic enzyme produced by Micrococcus luteus was investigated utilizing standard procedures for protein and enzyme purification…”
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Crystallizable HIV-1 protease derived from expression of the viral pol gene in Escherichia coli by Danley, D E, Geoghegan, K F, Scheld, K G, Lee, S E, Merson, J R, Hawrylik, S J, Rickett, G A, Ammirati, M J, Hobart, P M

“…A plasmid vector was used to express the HIV-1 pol open reading frame under the regulation of the bacterial trp promoter in Escherichia coli. This expression…”
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Vortex flow filtration of mammalian and insect cells by HAWRYLIK, S. J, WASILKO, D. J, PILLAR, J. S, CHENG, J. B, LEE, S. E

“…The use of vortex flow filtration for harvesting cells or conditioned medium from large scale bioreactors has proven to be an efficient, low shear method of…”
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Expression of human plasminogen activator inhibitor type-1 (PAI-1) in Escherichia coli as a soluble protein comprised of active and latent forms. Isolation and crystallization of latent PAI-1 by Franke, A E, Danley, D E, Kaczmarek, F S, Hawrylik, S J, Gerard, R D, Lee, S E, Geoghegan, K F

“…Expression of human recombinant plasminogen activator inhibitor type-1 (PAI-1) in Escherichia coli has led to crystallization of 'latent' PAI-1. Cleavage with…”
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