Search Results - "Hawley, Eric"

Digital Twins: A novel traceability concept for post-harvest handling by Dyck, George, Hawley, Eric, Hildebrand, Kurt, Paliwal, Jitendra

“…Digital Twins are a novel approach to systems engineering that can help control complex environments and interface humans with them. This is achieved by…”
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Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease by Richard, Arianne C, Peters, James E, Savinykh, Natalia, Lee, James C, Hawley, Eric T, Meylan, Françoise, Siegel, Richard M, Lyons, Paul A, Smith, Kenneth G C

“…Chronic inflammation in inflammatory bowel disease (IBD) results from a breakdown of intestinal immune homeostasis and compromise of the intestinal barrier…”
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The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells by Richard, Arianne C, Tan, Cuiyan, Hawley, Eric T, Gomez-Rodriguez, Julio, Goswami, Ritobrata, Yang, Xiang-Ping, Cruz, Anthony C, Penumetcha, Pallavi, Hayes, Erika T, Pelletier, Martin, Gabay, Odile, Walsh, Matthew, Ferdinand, John R, Keane-Myers, Andrea, Choi, Yongwon, O'Shea, John J, Al-Shamkhani, Aymen, Kaplan, Mark H, Gery, Igal, Siegel, Richard M, Meylan, Françoise

“…The TNF family cytokine TL1A (Tnfsf15) costimulates T cells and type 2 innate lymphocytes (ILC2) through its receptor DR3 (Tnfrsf25). DR3-deficient mice have…”
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PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2) by Hawley, Eric, Gehlhausen, Jeffrey, Karchugina, Sofiia, Chow, Hoi-Yee, Araiza-Olivera, Daniela, Radu, Maria, Smith, Abbi, Burks, Ciersten, Jiang, Li, Li, Xiaohong, Bessler, Waylan, Masters, Andrea, Edwards, Donna, Burgin, Callie, Jones, David, Yates, Charles, Clapp, D Wade, Chernoff, Jonathan, Park, Su-Jung

“…Abstract Neurofibromatosis Type II (NF2) is an autosomal dominant cancer predisposition syndrome in which germline haploinsufficiency at the NF2 gene confers a…”
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Ketotifen Modulates Mast Cell Chemotaxis to Kit-Ligand, but Does Not Impact Mast Cell Numbers, Degranulation, or Tumor Behavior in Neurofibromas of Nf1 -Deficient Mice by Burks, Ciersten A, Rhodes, Steven D, Bessler, Waylan K, Chen, Shi, Smith, Abbi, Gehlhausen, Jeffrey R, Hawley, Eric T, Jiang, Li, Li, Xiaohong, Yuan, Jin, Lu, Qingbo, Jacobsen, Max, Sandusky, George E, Jones, David R, Clapp, D Wade, Blakeley, Jaishri O

“…Neurofibromatosis Type 1 (NF1) is one of the most common genetic tumor predisposition syndromes in humans. Mutant results in dysregulated RAS allowing…”
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Cloning and expression of a zebrafish 5-HT2C receptor gene by Schneider, Henning, Fritzky, Luke, Williams, Jesse, Heumann, Christine, Yochum, Marissa, Pattar, Kala, Noppert, Grace, Mock, Vanessa, Hawley, Eric

“…The 5-HT2C receptor is one of 14 different serotonin (5-HT) receptors that control neural function and behavior. Here, we present the entire sequence of a…”
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Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF by Song, Yun-Jeong, Choi, In Ah, Meylan, Françoise, Demoruelle, M Kristen, Farley, Taylor, Richard, Arianne C, Hawley, Eric, Botson, John, Hong, Yoo Jin, Lee, Eun Young, Mian, Sabina R, Hamilton, Bartlett C, Thiele, Geoffrey M, Mikuls, Ted R, Gara, Naveen, Ward, Chris D, Lamberth, Sarah, Deane, Kevin D, Heller, Theo, Ward, Michael M, Lee, David M, Migone, Thi-Sau, Stohl, William, O'Dell, James R, Norris, Jill M, Holers, V Michael, Gregersen, Peter, Song, Yeong-Wook, Siegel, Richard M

“…The tumor necrosis factor (TNF) superfamily cytokine TNF-like protein 1A (TL1A) and its receptor DR3 are essential for diverse animal models of autoimmune…”
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Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2 by Wahle, Benjamin M, Hawley, Eric T, He, Yongzheng, Smith, Abbi E, Yuan, Jin, Masters, Andi R, Jones, David R, Gehlhausen, Jeffrey R, Park, Su-Jung, Conway, Simon J, Clapp, D Wade, Yates, Charles W

“…Mutations in the tumor suppressor gene lead to Neurofibromatosis type 2 (NF2), a tumor predisposition syndrome characterized by the development of schwannomas,…”
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Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling by Chen, Zhiguo, Li, Stephen, Mo, Juan, Hawley, Eric, Wang, Yong, He, Yongzheng, Brosseau, Jean-Philippe, Shipman, Tracey, Clapp, D Wade, Carroll, Thomas J, Le, Lu Q

“…Schwannomas are tumors of the Schwann cells that cause chronic pain, numbness, and potentially life-threatening impairment of vital organs. Despite the…”
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Correction: The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell-Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9-Producing T Cells by Richard, Arianne C, Tan, Cuiyan, Hawley, Eric T, Gomez-Rodriguez, Julio, Goswami, Ritobrata, Yang, Xiang-Ping, Cruz, Anthony C, Penumetcha, Pallavi, Hayes, Erika T, Pelletier, Martin, Gabay, Odile, Walsh, Matthew, Ferdinand, John R, Keane-Myers, Andrea, Choi, Yongwon, O'Shea, John J, Al-Shamkhani, Aymen, Kaplan, Mark H, Gery, Igal, Siegel, Richard M, Meylan, Françoise

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Enhancing traceability of wheat quality through the supply chain by Nadimi, Mohammad, Hawley, Eric, Liu, Jing, Hildebrand, Kurt, Sopiwnyk, Elaine, Paliwal, Jitendra

“…With the growing global population, the need for food is expected to grow tremendously in the next few decades. One of the key tools to address such growing…”
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Building a Data Linkage Foundation for Mother–Child Pharmacoepidemiology Research by Whitmore, Christine C., Hawley, R. Eric, Min, Jea Young, Mitchel, Ed, Daugherty, James R., Griffin, Marie R., Grijalva, Carlos G.

“…Background Expanding our understanding of the effects of maternal medication exposure through research is a public health priority and will help inform both…”
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Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1 by Mund, Julie A, Park, SuJung, Smith, Abbi E, He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J, Mitchell, Dana K, Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K, Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D, Clapp, D Wade

“…Neurofibromatosis type 1 (NF1) is a common cancer predisposition syndrome caused by mutations in the tumor suppressor gene. encodes neurofibromin, a…”
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Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17 by Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade

“…Neurofibromatosis type 1 (NF1) is a common cancer predisposition syndrome caused by mutations in the NF1 tumor suppressor gene. NF1 encodes neurofibromin, a…”
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Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK by Chang, Long-Sheng, Oblinger, Janet L, Smith, Abbi E, Ferrer, Marc, Angus, Steven P, Hawley, Eric, Petrilli, Alejandra M, Beauchamp, Roberta L, Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K, Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S, Gilbert, Thomas S K, Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A H, Masters, Andrea, Jones, David R, Yates, Charles W, Haggarty, Stephen J, La Rosa, Salvatore, Welling, D Bradley, Stemmer-Rachamimov, Anat O, Plotkin, Scott R, Gusella, James F, Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L, Blakeley, Jaishri O, Clapp, D Wade

“…Neurofibromatosis Type 2 (NF2) is an autosomal dominant genetic syndrome caused by mutations in the NF2 tumor suppressor gene resulting in multiple schwannomas…”
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The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells by Meylan, F, Hawley, E T, Barron, L, Barlow, J L, Penumetcha, P, Pelletier, M, Sciumè, G, Richard, A C, Hayes, E T, Gomez-Rodriguez, J, Chen, X, Paul, W E, Wynn, T A, McKenzie, A N J, Siegel, R M

“…The tumor necrosis factor (TNF)-family cytokine TL1A (TNFSF15) costimulates T cells and promotes diverse T cell-dependent models of autoimmune disease through…”
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Correction: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17 by Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D.Wade

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Remote supervision of autonomous agricultural sprayers: The farmer’s perspective by Edit, Uduak, Hawley, Eric, Mann, Danny

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A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas by Gehlhausen, Jeffrey R, Hawley, Eric, Wahle, Benjamin Mark, He, Yongzheng, Edwards, Donna, Rhodes, Steven D, Lajiness, Jacquelyn D, Staser, Karl, Chen, Shi, Yang, Xianlin, Yuan, Jin, Li, Xiaohong, Jiang, Li, Smith, Abbi, Bessler, Waylan, Sandusky, George, Stemmer-Rachamimov, Anat, Stuhlmiller, Timothy J, Angus, Steven P, Johnson, Gary L, Nalepa, Grzegorz, Yates, Charles W, Wade Clapp, D, Park, Su-Jung

“…Abstract Schwannomas are common, highly morbid and medically untreatable tumors that can arise in patients with germ line as well as somatic mutations in…”
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An Investigation of Molecular Pathways to Aid in Therapeutic Development for Neurofibromatosis Type 2 by Hawley, Eric Thomas

“…Neurofibromatosis type 2 (NF2) is an autosomal dominant cancer predisposition in which loss of heterozygosity at the NF2 gene locus leads to the development of…”
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