Search Results - "Hawksworth, G.M."

Quantification of biliary excretion and sinusoidal excretion of 5(6)-carboxy-2′,7′-dichlorofluorescein (CDF) in cultured hepatocytes isolated from Sprague Dawley, Wistar and Mrp2-deficient Wistar (TR−) rats by Ellis, L.C.J., Grant, M.H., Hawksworth, G.M., Weaver, R.J.

“…•A method to measure sinusoidal and canalicular efflux of CDF was presented.•Biliary efflux of CDF in Sprague Dawley and Wistar rats shows bi-phasic…”
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Autoregulation of 5-fluorouracil metabolism by McLeod, H.L., Sludden, J., Hardy, S.C., Lock, R.E., Hawksworth, G.M., Cassidy, J.

“…5-Fluorouracil (5-FU) is a commonly used anticancer agent for the treatment of gastrointestinal, head and neck, and breast tumours. This study determined the…”
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Population pharmacokinetics of single-dose intravenous paracetamol in children by Mohammed, B.S., Engelhardt, T., Cameron, G.A., Cameron, L., Hawksworth, G.M., Hawwa, A.F., McElnay, J., Helms, P.J., McLay, J.S.

“…To determine the pharmacokinetics (PK) of a new i.v. formulation of paracetamol (Perfalgan) in children ≤15 yr of age. After obtaining written informed…”
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Induction, regulation, degradation, and biological significance of mammalian metallothioneins by Miles, A T, Hawksworth, G M, Beattie, J H, Rodilla, V

“…MTs are small cysteine-rich metal-binding proteins found in many species and, although there are differences between them, it is of note that they have a great…”
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Site specific drug and xenobiotic induced renal toxicity by Hawksworth, G.M.

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Characterization of the inspiratory manoeuvre when asthmatics inhale through a Turbohaler pre- and post-counselling in a community pharmacy by HAWKSWORTH, G.M, JAMES, L, CHRYSTYN, H

“…Dose emission from a Turbohaler®has been shown to be dependent on the rate of inhalation, with an optimal flow of 60lmin−1recommended. Some patients may need…”
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Haloalkene cysteine conjugate transport in cultured human proximal tubular cells by McGoldrick, T., Lock, E.A., Hawksworth, G.M.

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Regulation of deiodinase activity by cellular redox status by Gregory, L.G., Cameron, G.A., Harrison, A., Smith, D.A., Hawksworth, G.M.

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The effect of papillotoxins on cuitured human renal medullary interstitial cells by Tisocki, K., Hawksworth, G.M., Whiting, P.

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Selective antagonism of the AT1 receptor inhibits angiotensin II stimulated DNA and protein synthesis in primary cultures of human proximal tubular cells by Chatterjee, P.K., Weerackody, R.P., Mistry, S.K., Hawksworth, G.M., Mclay, J.S.

“…Selective antagonism of the AT1 receptor inhibits angiotensin II stimulated DNA and protein synthesis in primary cultures of human proximal tubular cells. The…”
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A001 Evidence for differential autocrine regulation of natriuretic peptide receptor gene expression by locally synthesised natriuretic peptides by Mistry, S., Chatterjee, P.K., Espie, G., Fouletier, C., Hawksworth, G.M., Henderson, L., McLay, J.S.

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The reversal of experimental cyclosporin A nephrotoxicity by thromboxane synthetase inhibition by Grieve, E M, Hawksworth, G M, Simpson, J G, Whiting, P H

“…The ability of thromboxane synthetase inhibition to reverse acute cyclosporin A (CsA)-induced nephrotoxicity in the rat was investigated. CsA administration…”
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Drug metabolism and viability studies in cryopreserved rat hepatocytes by Coundouris, J A, Grant, M H, Simpson, J G, Hawksworth, G M

“…Rat hepatocytes were cryopreserved optimally by freezing them at 1 degrees C/min to -80 degrees C in cryoprotectant medium containing either 20% (v/v)…”
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Maintenance of glucose uptake in suspensions and cultures of human renal proximal tubular cells by McLaren, J, Whiting, P H, Hawksworth, G M

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Effect of thromboxane synthetase inhibition and angiotensin converting enzyme inhibition on acute cyclosporin A nephrotoxicity by Grieve, E M, Hawksworth, G M, Simpson, J G, Whiting, P H

“…One component of cyclosporin A (CsA) nephrotoxicity is thromboxane (Tx) A2 induced renal vasoconstriction. This study was designed to investigate whether…”
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Kinetics of paraquat elimination in the dog by Hawksworth, G M, Bennett, P N, Davies, D S

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Arachidonic-acid-dependent metabolism of 2-bromoethanamine to a toxic metabolite in rat medullary interstitial cell cultures by Grieve, E M, Whiting, P H, Hawksworth, G M

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Effect of Atenolol and Metoprolol on Exercise and Post-Exercise Pulse and Blood Pressure, 24 Hours after Administration by Scott, A.K., Rigby, J.W., Webster, J., Hawksworth, G.M., Petrie, J.C., Lovell, H.G.

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