Search Results - "Hawkins, Virginia E."

Purinergic regulation of vascular tone in the retrotrapezoid nucleus is specialized to support the drive to breathe by Hawkins, Virginia E, Takakura, Ana C, Trinh, Ashley, Malheiros-Lima, Milene R, Cleary, Colin M, Wenker, Ian C, Dubreuil, Todd, Rodriguez, Elliot M, Nelson, Mark T, Moreira, Thiago S, Mulkey, Daniel K

“…Cerebral blood flow is highly sensitive to changes in CO /H where an increase in CO /H causes vasodilation and increased blood flow. Tissue CO /H also…”
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Kir4.1 channels contribute to astrocyte CO2/H+-sensitivity and the drive to breathe by Cleary, Colin M., Browning, Jack L., Armbruster, Moritz, Sobrinho, Cleyton R., Strain, Monica L., Jahanbani, Sarvin, Soto-Perez, Jaseph, Hawkins, Virginia E., Dulla, Chris G., Olsen, Michelle L., Mulkey, Daniel K.

“…Astrocytes in the retrotrapezoid nucleus (RTN) stimulate breathing in response to CO 2 /H + , however, it is not clear how these cells detect changes in CO 2…”
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Epilepsy-Associated KCNQ2 Channels Regulate Multiple Intrinsic Properties of Layer 2/3 Pyramidal Neurons by Niday, Zachary, Hawkins, Virginia E, Soh, Heun, Mulkey, Daniel K, Tzingounis, Anastasios V

“…KCNQ2 potassium channels are critical for normal brain function, as both loss-of-function and gain-of-function KCNQ2 variants can lead to various forms of…”
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Epilepsy-Associated KCNQ2 Channels Regulate Multiple Intrinsic Properties of Layer 2/3 Pyramidal Neurons by Niday, Zachary, Hawkins, Virginia E, Soh, Heun, Mulkey, Daniel K, Tzingounis, Anastasios V

“…KCNQ2 potassium channels are critical for normal brain function, as both loss-of-function and gain-of-function KCNQ2 variants can lead to various forms of…”
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MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats by Patterson, Kelsey C, Hawkins, Virginia E, Arps, Kara M, Mulkey, Daniel K, Olsen, Michelle L

“…Since the identification of MECP2 as the causative gene in the majority of Rett Syndrome (RTT) cases, transgenic mouse models have played a critical role in…”
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Metabotropic Glutamate Receptors Protect Oligodendrocytes from Acute Ischemia in the Mouse Optic Nerve by Butt, Arthur M., Vanzulli, Ilaria, Papanikolaou, Maria, De La Rocha, Irene Chacon, Hawkins, Virginia E.

“…Studies by Bruce Ransom and colleagues have made a major contribution to show that white matter is susceptible to ischemia/hypoxia. White matter contains axons…”
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HCN channels contribute to serotonergic modulation of ventral surface chemosensitive neurons and respiratory activity by Hawkins, Virginia E, Hawryluk, Joanna M, Takakura, Ana C, Tzingounis, Anastasios V, Moreira, Thiago S, Mulkey, Daniel K

“…Chemosensitive neurons in the retrotrapezoid nucleus (RTN) provide a CO2/H(+)-dependent drive to breathe and function as an integration center for the…”
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MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats by Patterson, Kelsey C, Hawkins, Virginia E, Arps, Kara M, Mulkey, Daniel K, Olsen, Michelle L

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Molecular underpinnings of ventral surface chemoreceptor function: focus on KCNQ channels by Mulkey, Daniel K., Hawkins, Virginia E., Hawryluk, Joanna M., Takakura, Ana C., Moreira, Thiago S., Tzingounis, Anastasios V.

“…Central chemoreception is the mechanism by which CO2/H+‐sensitive neurons (i.e. chemoreceptors) regulate breathing in response to changes in tissue CO2/H+…”
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Astrocyte‐specific deletion of Kir4.1 increases normoxic ventilation after acclimatization to chronic sustained hypoxia by Moya, Esteban A., Hawkins, Virginia E., Yip, Gigi, Mulkey, Daniel K., Powell, Frank L.

“…Chronic sustained hypoxia (CH) produces ventilatory acclimatization to hypoxia (VAH), which involves time‐dependent increases of ventilation in normoxia and…”
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Conditional knockout of astrocytic Kir4.1 channels impairs central respiratory drive despite maintaining a subset of Cx26 + astrocytes within the RTN by Hawkins, Virginia E, Kolling, Fred W, Nelson, Craig E, Mulkey, Daniel K

“…Abstract only Central chemoreception is the mechanism by which the brain regulates breathing in response to changes in tissue CO 2 /H + . The retrotrapezoid…”
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Kir4.1 channels contribute to astrocyte CO 2 /H + -sensitivity and the drive to breathe by Cleary, Colin M, Browning, Jack L, Armbruster, Moritz, Sobrinho, Cleyton R, Strain, Monica L, Jahanbani, Sarvin, Soto-Perez, Jaseph, Hawkins, Virginia E, Dulla, Chris G, Olsen, Michelle L, Mulkey, Daniel K

“…Astrocytes in the retrotrapezoid nucleus (RTN) stimulate breathing in response to CO /H , however, it is not clear how these cells detect changes in CO /H …”
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