Search Results - "Hawkins, Janet L."

Synthesis of 4‑Arylthieno[2,3‑b]pyridines and 4‑Aminothieno[2,3‑b]pyridines via a Regioselective Bromination of Thieno[2,3‑b]pyridine by Lucas, Simon C. C, Moore, Jane E, Donald, Craig S, Hawkins, Janet L

“…The first regioselective, mild bromination of thieno­[2,3-b]­pyridine is described herein. The reaction proceeds with selectivity toward the 4-position (87%…”
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Pyrimidinone Nicotinamide Mimetics as Selective Tankyrase and Wnt Pathway Inhibitors Suitable for in Vivo Pharmacology by Johannes, Jeffrey W, Almeida, Lynsie, Barlaam, Bernard, Boriack-Sjodin, P. Ann, Casella, Robert, Croft, Rosemary A, Dishington, Allan P, Gingipalli, Lakshmaiah, Gu, Chungang, Hawkins, Janet L, Holmes, Jane L, Howard, Tina, Huang, Jian, Ioannidis, Stephanos, Kazmirski, Steven, Lamb, Michelle L, McGuire, Thomas M, Moore, Jane E, Ogg, Derek, Patel, Anil, Pike, Kurt G, Pontz, Timothy, Robb, Graeme R, Su, Nancy, Wang, Haiyun, Wu, Xiaoyun, Zhang, Hai-Jun, Zhang, Yue, Zheng, Xiaolan, Wang, Tao

“…The canonical Wnt pathway plays an important role in embryonic development, adult tissue homeostasis, and cancer. Germline mutations of several Wnt pathway…”
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Selective palladium-catalysed amination of 4-chloropyridines with benzylamines using the Josiphos ligand by Hawkins, Janet L., Gregson, Clare L., Hassall, Lorraine A., Holmes, Jane L.

“…[Display omitted] A synthetic strategy for the synthesis of a library of 4-N-benzylamino-2-N-phenyl-pyridines is herein described. The approach involves a…”
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