Search Results - "Hawkins, E.D"
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Quantal and graded stimulation of B lymphocytes as alternative strategies for regulating adaptive immune responses
Published in Nature communications (06-09-2013)“…Lymphocytes undergo a typical response pattern following stimulation in vivo : they proliferate, differentiate to effector cells, cease dividing and…”
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2
single-cell pedigree analysis of alternative stochastic lymphocyte fates
Published in Proceedings of the National Academy of Sciences - PNAS (11-08-2009)“…In contrast to most stimulated lymphocytes, B cells exposed to Toll-like receptor 9 ligands are nonself-adherent, allowing individual cells and families to be…”
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3
model of immune regulation as a consequence of randomized lymphocyte division and death times
Published in Proceedings of the National Academy of Sciences - PNAS (20-03-2007)“…The magnitude of an adaptive immune response is controlled by the interplay of lymphocyte quiescence, proliferation, and apoptosis. How lymphocytes integrate…”
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4
Scribble acts as an oncogene in Eμ-myc-driven lymphoma
Published in Oncogene (03-03-2016)“…Scribble complex proteins maintain apicobasal polarity, regulate cell fate determination and function as tumour suppressors in epithelial tissue. Despite…”
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Upsides and downsides to polarity and asymmetric cell division in leukemia
Published in Oncogene (24-11-2008)“…The notion that polarity regulators can act as tumor suppressors in epithelial cells is now well accepted. The function of these proteins in lymphocytes is…”
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The effect of correlations on the population dynamics of lymphocytes
Published in Journal of theoretical biology (21-05-2010)“…Recent studies of the population dynamics of a system of lymphocytes in an in vitro immune response have reported strong correlations in cell division times,…”
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Cardiovascular and antilipolytic effects of the adenosine agonist GR79236
Published in Pharmacology (01-10-1995)“…Adenosine is known to produce cardiovascular effects such as bradycardia and hypotension via activation of myocardial (A1) and vascular (A2) receptors and…”
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