Search Results - "Hawkins, E. D."

Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space by Akinduro, O., Weber, T. S., Ang, H., Haltalli, M. L. R., Ruivo, N., Duarte, D., Rashidi, N. M., Hawkins, E. D., Duffy, K. R., Lo Celso, C.

“…Leukaemia progressively invades bone marrow (BM), outcompeting healthy haematopoiesis by mechanisms that are not fully understood. Combining cell number…”
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single-cell pedigree analysis of alternative stochastic lymphocyte fates by Hawkins, E.D, Markham, J.F, McGuinness, L.P, Hodgkin, P.D

“…In contrast to most stimulated lymphocytes, B cells exposed to Toll-like receptor 9 ligands are nonself-adherent, allowing individual cells and families to be…”
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model of immune regulation as a consequence of randomized lymphocyte division and death times by Hawkins, E.D, Turner, M.L, Dowling, M.R, van Gend, C, Hodgkin, P.D

“…The magnitude of an adaptive immune response is controlled by the interplay of lymphocyte quiescence, proliferation, and apoptosis. How lymphocytes integrate…”
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Metabolizable protein supply while grazing dormant winter forage during heifer development alters pregnancy and subsequent in-herd retention rate by Mulliniks, J. T, Hawkins, D. E, Kane, K. K, Cox, S. H, Torell, L. A, Scholljegerdes, E. J, Petersen, M. K

“…Two studies were conducted to evaluate effects of post-weaning management of British crossbred heifers on growth and reproduction. In Exp. 1, 239 spring-born,…”
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effect of increasing amount of glucogenic precursors on reproductive performance in young postpartum range cows by Mulliniks, J.T, Kemp, M.E, Cox, S.H, Hawkins, D.E, Cibils, A.F, VanLeeuwen, D.M, Petersen, M.K

“…Supplementing CP and propionate salts (PS) may improve economic returns in young range beef cows by increasing the dietary supply of glucogenic precursors. A…”
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The effect of correlations on the population dynamics of lymphocytes by Wellard, C., Markham, J., Hawkins, E.D., Hodgkin, P.D.

“…Recent studies of the population dynamics of a system of lymphocytes in an in vitro immune response have reported strong correlations in cell division times,…”
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High Periconceptional Protein Intake Modifies Uterine and Embryonic Relationships Increasing Early Pregnancy Losses and Embryo Growth Retardation in Sheep by Meza-Herrera, CA, Ross, TT, Hallford, DM, Hawkins, DE, Gonzalez-Bulnes, A

“…The effects of supplemented protein level (PL) during the periconceptional period and their interaction with body condition were evaluated in sheep…”
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Insertion of Inhbb into the Inhba locus rescues the Inhba -null phenotype and reveals new activin functions by Matzuk, Martin M, Brown, Chester W, Houston-Hawkins, Dianne E, Woodruff, Teresa K

“…The activins (dimers of βA or βB subunits, encoded by the genes Inhba and Inhbb, respectively) are TGF-β superfamily members that have roles in reproduction…”
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Effects of supplements that contain increasing amounts of metabolizable protein with or without Ca-propionate salt on postpartum interval and nutrient partitioning in young beef cows by Waterman, R.C, Sawyer, J.E, Mathis, C.P, Hawkins, D.E, Donart, G.B, Petersen, M.K

“…Cattle grazing winter range forages exhibit interannual variation in response to supplementation. This variation may be mediated by circulating concentrations…”
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Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia by Waibel, M, Vervoort, S J, Kong, I Y, Heinzel, S, Ramsbottom, K M, Martin, B P, Hawkins, E D, Johnstone, R W

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Quantal and graded stimulation of B lymphocytes as alternative strategies for regulating adaptive immune responses by Hawkins, E.D., Turner, M.L., Wellard, C.J., Zhou, J.H.S., Dowling, M.R., Hodgkin, P.D.

“…Lymphocytes undergo a typical response pattern following stimulation in vivo : they proliferate, differentiate to effector cells, cease dividing and…”
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Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19 by Peng, Yanchun, Mentzer, Alexander J., Liu, Guihai, Yao, Xuan, Yin, Zixi, Dong, Danning, Dejnirattisai, Wanwisa, Rostron, Timothy, Supasa, Piyada, Liu, Chang, López-Camacho, César, Slon-Campos, Jose, Zhao, Yuguang, Stuart, David I., Paesen, Guido C., Grimes, Jonathan M., Antson, Alfred A., Bayfield, Oliver W., Hawkins, Dorothy E. D. P., Ker, De-Sheng, Wang, Beibei, Turtle, Lance, Subramaniam, Krishanthi, Thomson, Paul, Zhang, Ping, Dold, Christina, Ratcliff, Jeremy, Simmonds, Peter, de Silva, Thushan, Sopp, Paul, Wellington, Dannielle, Rajapaksa, Ushani, Chen, Yi-Ling, Salio, Mariolina, Napolitani, Giorgio, Paes, Wayne, Borrow, Persephone, Kessler, Benedikt M., Fry, Jeremy W., Schwabe, Nikolai F., Semple, Malcolm G., Baillie, J. Kenneth, Moore, Shona C., Openshaw, Peter J. M., Ansari, M. Azim, Dunachie, Susanna, Barnes, Eleanor, Frater, John, Kerr, Georgina, Goulder, Philip, Lockett, Teresa, Levin, Robert, Zhang, Yonghong, Jing, Ronghua, Ho, Ling-Pei, Cornall, Richard J., Conlon, Christopher P., Klenerman, Paul, Screaton, Gavin R., Mongkolsapaya, Juthathip, McMichael, Andrew, Knight, Julian C., Ogg, Graham, Dong, Tao

“…The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines and therapeutics will depend on understanding viral immunity. We…”
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Scribble acts as an oncogene in Eμ-myc-driven lymphoma by Hawkins, E D, Oliaro, J, Ramsbottom, K M, Newbold, A, Humbert, P O, Johnstone, R W, Russell, S M

“…Scribble complex proteins maintain apicobasal polarity, regulate cell fate determination and function as tumour suppressors in epithelial tissue. Despite…”
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Upsides and downsides to polarity and asymmetric cell division in leukemia by Hawkins, E D, Russell, S M

“…The notion that polarity regulators can act as tumor suppressors in epithelial cells is now well accepted. The function of these proteins in lymphocytes is…”
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Effect of increasing levels of undegradable intake protein on metabolic and endocrine factors in estrous cycling beef heifers by Kane, K.K, Hawkins, D.E, Pulsipher, G.D, Denniston, D.J, Krehbiel, C.R, Thomas, M.G, Petersen, M.K, Hallford, D.M, Remmenga, M.D, Roberts, A.J

“…To determine the influence of three levels of undegradable intake protein (UIP) supplementation on metabolic and endocrine factors that influence reproduction,…”
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The Mechanism of SARS-CoV-2 Nucleocapsid Protein Recognition by the Human 14-3-3 Proteins by Tugaeva, Kristina V., Hawkins, Dorothy E.D.P., Smith, Jake L.R., Bayfield, Oliver W., Ker, De-Sheng, Sysoev, Andrey A., Klychnikov, Oleg I., Antson, Alfred A., Sluchanko, Nikolai N.

“…[Display omitted] •SARS-CoV-2 nucleocapsid protein (N) binds to all seven human 14-3-3 isoforms.•This association with 14-3-3 strictly depends on…”
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An increase in serum lipids increases luteal lipid content and alters the disappearance rate of progesterone in cows by Hawkins, D.E. (New Mexico State Univ., Las Cruces), Niswender, K.D, Oss, G.M, Moeller, C.L, Odde, K.G, Sawyer, H.R, Niswender, G.D

“…To determine whether an increase in serum lipids alters the area occupied by lipid droplets in steroidogenic luteal cells and(or) clearance rates of…”
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Structural atlas of a human gut crassvirus by Bayfield, Oliver W., Shkoporov, Andrey N., Yutin, Natalya, Khokhlova, Ekaterina V., Smith, Jake L. R., Hawkins, Dorothy E. D. P., Koonin, Eugene V., Hill, Colin, Antson, Alfred A.

“…CrAssphage and related viruses of the order Crassvirales (hereafter referred to as crassviruses) were originally discovered by cross-assembly of metagenomic…”
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Insights into a viral motor: the structure of the HK97 packaging termination assembly by Hawkins, Dorothy E D P, Bayfield, Oliver W, Fung, Herman K H, Grba, Daniel N, Huet, Alexis, Conway, James F, Antson, Alfred A

“…Abstract Double-stranded DNA viruses utilise machinery, made of terminase proteins, to package viral DNA into the capsid. For cos bacteriophage, a defined…”
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Genetic differentiation among geographically isolated populations of Criollo cattle and their divergence from other Bos taurus breeds by Russell, N. D, Rios, J, Erosa, G, Remmenga, M. D, Hawkins, D. E

“…The microsatellites HEL5, HEL9, INRA063, and BM2113 were used to analyze genetic similarities and differences of geographically isolated Criollo cattle herds…”
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