Search Results - "Hawkes, Aaron R"

Depletion of conventional CD4 + T cells is required for robust priming and dissemination of tumor antigen-specific CD8 + T cells in the setting of anti-CD4 therapy by Ramirez, Delaney E, Dragnev, Christo P C, Searles, Tyler G, Spicer, Nathaniel, Chen, Tiffany, Lines, J Louise, Hawkes, Aaron R, Davis, Wilson L, Mohamed, Asmaa, Shirai, Keisuke, Phillips, Joseph D, Rosato, Pamela C, Huang, Yina H, Turk, Mary Jo

“…Overcoming immune suppression is a major barrier to eliciting potent CD8+ T cell responses against cancer. Treatment with anti-CD4 monoclonal antibody is an…”
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Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma by Molodtsov, Aleksey K., Khatwani, Nikhil, Vella, Jennifer L., Lewis, Kathryn A., Zhao, Yanding, Han, Jichang, Sullivan, Delaney E., Searles, Tyler G., Preiss, Nicholas K., Shabaneh, Tamer B., Zhang, Peisheng, Hawkes, Aaron R., Malik, Brian T., Kolling, Fred W., Usherwood, Edward J., Wong, Sandra L., Phillips, Joseph D., Shirai, Keisuke, Angeles, Christina V., Yan, Shaofeng, Curiel, Tyler J., Huang, Yina H., Cheng, Chao, Turk, Mary Jo

“…The nature of the anti-tumor immune response changes as primary tumors progress and metastasize. We investigated the role of resident memory (Trm) and…”
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Temporal requirements for TGF-β and IL-7 in generating resident memory T cell responses to melanoma by Ramirez, Delaney E, Hawkes, Aaron R, Searles, Tyler G., Wang, Chen-Yu, Nemeth, Alexander N, Pioli, Patricia A, Turk, Mary Jo

“…Resident memory CD8 +(T RM) cells persist in tissues and are critical mediators of the host anti-tumor response. We previously demonstrated that protective,…”
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Abstract LB360: Type-1 interferon sensing is critical for CD8+ resident memory (TRM) cell generation in tumor-draining lymph nodes by Khatwani, Nikhil, Molodtsov, Aleksey, Messier, Cameron, Han, Jichang, Searles, Tyler Glenn, Hawkes, Aaron R, Kolling IV, Fred W, Turk, Mary Jo

“…CD8+ tissue resident memory T cells (TRM) are potent mediators of anti-tumor immunity. We have previously identified a population of lymph node resident memory…”
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