Search Results - "Hawke, D H"

Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules by Guo, H, Gao, M, Lu, Y, Liang, J, Lorenzi, P L, Bai, S, Hawke, D H, Li, J, Dogruluk, T, Scott, K L, Jonasch, E, Mills, G B, Ding, Z

“…Aberrant AKT activation is prevalent across multiple human cancer lineages providing an important new target for therapy. Twenty-two independent…”
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Cloning of Drosophila Choline Acetyltransferase cDNA by Itoh, Nobuyuki, Slemmon, J. Randall, Hawke, David H., Williamson, Rodney, Morita, Elaine, Itakura, Keiichi, Roberts, Eugene, Shively, John E., Crawford, Garrett D., Salvaterra, Paul M.

“…Choline acetyltransferase (EC 2.3.1.6) is the biosynthetic enzyme for the neurotransmitter acetylcholine. To isolate choline acetyltransferase cDNA clones, a…”
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Isolation and primary structure of the califins, three biologically active egg-laying hormone-like peptides from the atrial gland of Aplysia californica by Rothman, B S, Hawke, D H, Brown, R O, Lee, T D, Dehghan, A A, Shively, J E, Mayeri, E

“…The atrial gland of the marine mollusk Aplysia californica contains several biologically active peptides that are thought to be important in reproductive…”
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Isolation and structure of the principal products of preproglucagon processing, including an amidated glucagon-like peptide by Andrews, P C, Hawke, D H, Lee, T D, Legesse, K, Noe, B D, Shively, J E

“…The principal products derived from in vivo processing of anglerfish preproglucagon II were isolated and their structures determined. The structures were…”
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A general approach for characterizing glycosylation sites of glycoproteins by Hsi, K L, Chen, L, Hawke, D H, Zieske, L R, Yuan, P M

“…Recent advances in glycobiology have greatly stimulated carbohydrate research; however, improving techniques for identification and isolation of specific…”
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The use of micropreparative electrophoresis of protein/peptide isolations for primary structure determinations by Sheer, D G, Yamane, D K, Hawke, D H, Yuan, P M

“…High-performance electrophoresis chromatography (HPEC) is a recent development that features continuous-elution gel electrophoresis for isolating proteins or…”
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Microsequence analysis of peptides and proteins: trimethylsilylisothiocyanate as a reagent for COOH-terminal sequence analysis by Hawke, D H, Lahm, H W, Shively, J E, Todd, C W

“…A reinvestigation of the isothiocyanate-based chemistry for cyclic degradations of peptides and proteins revealed that the reagent trimethylsilylisothiocyanate…”
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Synergy between interleukin-2 and a second factor in the long-term growth of human T cells by MILLS, B. J, SHIVELY, J. E, MITSKY, P. S, HAWKE, D. H, FORMAN, S. J, WRIGHT, C. L, TODD, C. W

“…It has recently been shown that factors in addition to interleukin-2 (IL-2) are required for the proliferation or differentiation of at least some murine…”
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Identification of a long form of cystatin from human saliva by rapid microbore HPLC mapping by Hawke, D H, Yuan, P M, Wilson, K J, Hunkapiller, M W

“…Microbore HPLC methodology permits rapid and sensitive mapping of human saliva proteins. Saliva is sampled and processed in less than one hour, greatly…”
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Identification and primary structural analysis of peptide II, an end-product of precursor processing in cells R3-R14 of Aplysia by Rothman, B S, Sigvardt, K A, Hawke, D H, Brown, R O, Shively, J E, Mayeri, E

“…Peptide II, which is encoded on a gene for a precursor protein in abdominal ganglion neurons R3-R14, was purified from extracts of abdominal ganglia of Aplysia…”
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Microsequence analysis of peptides and proteins. V. Design and performance of a novel gas-liquid-solid phase instrument by Hawke, D H, Harris, D C, Shively, J E

“…We describe the construction and performance of a novel, automated, Edman chemistry-based microsequencer. The reagent and solvent delivery system, the reaction…”
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Abstract P1-05-05: eEF1A2 facilitates PTEN-GSK3β mediated Aurora-A protein degradation during S-G2 phase inactivated in PTEN-deficient breast cancer by Treekitkarnmongkol, W, Solis, LM, Kai, K, Thompson, AM, Tian, W, Wistuba, II, Sasai, K, Jltsumori, Y, Sahin, AA, Hawke, DH, Lee, JM, Qin, L, Bawa-Khalfe, T, Rad, R, Wong, KK, Abbott, CM, Katayama, H, Sen, S

“…Abstract The AURKA gene, encoding Aurora kinase-A (Aurora-A), is frequently amplified and overexpressed across multiple cancer types correlating with poor…”
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Proteomic analysis of nipple aspirate fluid from women with early-stage breast cancer using isotope-coded affinity tags and tandem mass spectrometry reveals differential expression of vitamin D binding protein by Pawlik, Timothy M, Hawke, David H, Liu, Yanna, Krishnamurthy, Savitri, Fritsche, Herbert, Hunt, Kelly K, Kuerer, Henry M

“…Isotope-coded affinity tag (ICAT) tandem mass spectrometry (MS) allows for qualitative and quantitative analysis of paired protein samples. We sought to…”
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Partial amino acid sequence analyses of human placental insulin receptor by Fujita-Yamaguchi, Y, Hawke, D H, Shively, J E, Choi, S

“…Tryptic peptides were isolated from human insulin receptor (1.8 nmol) by sequential reverse-phase HPLC on SynChropak RP-C8 and Vydac C-18. Nearly 20 peptides…”
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P70-S Despite Rumors to the Contrary, PCNA Really IS Phosphorylated by Hawke, D. H., Wang, S., Nakajima, Y., Hung, M., Kobayashi, R.

“…Proliferating cell nuclear antigen (PCNA) is a small nuclear protein that plays a central role in DNA replication. Although it has been intensely studied,…”
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Routine fast atom bombardment mass spectral analysis of high molecular weight peptides--atrial gland peptides from Aplysia californica by Lee, T D, Legesse, K, Hawke, D H, Shively, J E, Rothman, B S, Mayeri, E

“…Three peptides isolated from the atrial glands of Aplysia californica were analysed by Fast Atom Bombardment Mass Spectrometry. Survey scans over the mass…”
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The use of micropreparative electrophoresis of protein/peptide isolations for primary structure determinations by Sheer, D G, Yamane, D K, Hawke, D H, Yuan, P M

“…High-performance electrophoresis chromatography (HPEC) is a recent development that features continuous-elution gel electrophoresis for isolating proteins or…”
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Diagnostic protein discovery using liquid chromatography/mass spectrometry for proteolytic peptide targeting by Koomen, John M., Zhao, Haitao, Li, Donghui, Nasser, Waleed, Hawke, David H., Abbruzzese, James L., Baggerly, Keith A., Kobayashi, Ryuji

“…A peptide targeting method has been developed for diagnostic protein discovery, which combines proteolytic digestion of fractionated plasma proteins and liquid…”
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Homocystinuria: a study with low-methionine diet in three patients by Sardharwalla, I B, Jackson, S H, Hawke, H D, Sass-Kortsak, A

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