Search Results - "Hawgood, S."

The pulmonary collectins and surfactant metabolism by Hawgood, S, Poulain, F R

“…Lung surfactant covers and stabilizes a large, delicate surface at the interface between the host and the environment. The surfactant system is placed at risk…”
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Surfactant protein D deficiency influences allergic immune responses by Schaub, B., Westlake, R. M., He, H., Arestides, R., Haley, K. J., Campo, M., Velasco, G., Bellou, A., Hawgood, S., Poulain, F. R., Perkins, D. L., Finn, P. W.

“…Summary Background The collectin surfactant protein D (SP‐D) confers protection against pulmonary infection and inflammation. Recent data suggest a role for…”
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Surfactant proteins in pulmonary alveolar proteinosis in adults by Brasch, F, Birzele, J, Ochs, M, Guttentag, S.H, Schoch, O.D, Boehler, A, Beers, M.F, Muller, K.M, Hawgood, S, Johnen, G

“…Pulmonary alveolar proteinosis (PAP) is a rare disorder characterised histologically by an intra-alveolar accumulation of fine granular eosinophilic and…”
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Pulmonary surfactant apoproteins: a review of protein and genomic structure by Hawgood, S

“…In recent years, as the complexity of the surfactant system has become more apparent, investigators with an increasingly diverse set of skills have been…”
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Early variable-flow nasal continuous positive airway pressure in infants 1000 grams at birth by Jegatheesan, P, Keller, R L, Hawgood, S

“…To compare the incidence of chronic lung disease (CLD) in extremely low birth weight (ELBW, < or =1000 g) infants before and after the introduction of early,…”
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Surfactant Protein D of the Innate Immune Defence is Inversely Associated with Human Obesity and SP‐D Deficiency Infers Increased Body Weight in Mice by Sorensen, G. L., Hjelmborg, J. v. B., Leth‐Larsen, R., Schmidt, V., Fenger, M., Poulain, F., Hawgood, S., Sørensen, T. I. A., Kyvik, K. O., Holmskov, U.

“…Surfactant protein D (SP‐D) is a key regulator of pathogen‐induced inflammation. SP‐D is further involved in lipid homeostasis in mouse lung and circulation…”
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Intracellular and Intraalveolar Localization of Surfactant Protein A (SP-A) in the Parenchymal Region of the Human Lung by Ochs, Matthias, Johnen, Georg, Muller, Klaus-Michael, Wahlers, Thorsten, Hawgood, Samuel, Richter, Joachim, Brasch, Frank

“…Although it is clearly established that surfactant protein A (SP-A) is secreted by type II pneumocytes as a component of pulmonary surfactant, its secretion…”
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Structures and properties of the surfactant-associated proteins by HAWGOOD, S, SHIFFER, K

“…The importance of surface forces to the mechanical properties of the lung were first recognized just over sixty years ago. The subject apparently received…”
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The role of surfactant protein D in the colonisation of the respiratory tract and onset of bacteraemia during pneumococcal pneumonia by Jounblat, R, Clark, H, Eggleton, P, Hawgood, S, Andrew, P W, Kadioglu, A

“…We have shown previously that surfactant protein D (SP-D) binds and agglutinates Streptococcus pneumoniae in vitro. In this study, the role of SP-D in innate…”
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Surfactant protein genes and human disease: The plot thickens by Hawgood, S

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Specific binding of surfactant apoprotein SP-A to rat alveolar macrophages by Pison, U, Wright, J R, Hawgood, S

“…Surfactant protein A (SP-A) influences the function of alveolar macrophages in vitro. In this study the characteristics of the binding of 125I-labeled SP-A to…”
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Surfactant apoprotein Mr = 26,000-36,000 enhances uptake of liposomes by type II cells by Wright, J.R., Wager, R.E., Hawgood, S., Dobbs, L., Clements, J.A.

“…The alveolar type II cell which synthesizes and secretes surfactant also plays a major role in the reuptake of surfactant lipids. In a recent in vivo study we…”
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Nucleotide and Amino Acid Sequences of Pulmonary Surfactant Protein SP 18 and Evidence for Cooperation between SP 18 and SP 28-36 in Surfactant Lipid Adsorption by Hawgood, Samuel, Benson, Bradley J., Schilling, James, Damm, Deborah, Clements, John A., White, R. Tyler

“…Pulmonary surfactant is a lipid-rich material that promotes alveolar stability by lowering the surface tension at the air-fluid interface in the peripheral air…”
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Fetoscopic temporary tracheal occlusion by means of detachable balloon for congenital diaphragmatic hernia by Harrison, Michael R., Albanese, Craig T., Hawgood, Samuel B., Farmer, Diana L., Farrell, Jody A., Sandberg, Per L., Filly, Roy A.

“…Occlusion of the fetal trachea blocks the egress of fetal lung fluid and stimulates the growth of hypoplastic lungs in fetuses with diaphragmatic hernia…”
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The major lung surfactant protein, SP 28-36, is a calcium-dependent, carbohydrate-binding protein by Haagsman, H P, Hawgood, S, Sargeant, T, Buckley, D, White, R T, Drickamer, K, Benson, B J

“…SP 28-36, a major protein of pulmonary surfactant, has striking amino acid sequence homology with soluble mannose-binding proteins isolated from rat liver and…”
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Effects of mechanical factors on growth and maturation of the lung in fetal sheep by Joe, P, Wallen, L D, Chapin, C J, Lee, C H, Allen, L, Han, V K, Dobbs, L G, Hawgood, S, Kitterman, J A

“…Previous fetal studies indicated that endocrine factors control surfactant maturation, whereas mechanical forces affect lung growth, but not surfactant. We…”
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Changes in lipid structure produced by surfactant proteins SP-A, SP-B, and SP-C by Williams, M C, Hawgood, S, Hamilton, R L

“…Pulmonary surfactant phospholipids may assume several different structures including tubular myelin, unilamellar and multilamellar vesicles, and others. These…”
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Pulmonary Surfactant and Its Components Inhibit Secretion of Phosphatidylcholine from Cultured Rat Alveolar Type II Cells by Dobbs, Leland G., Wright, Jo Rae, Hawgood, Samuel, Gonzalez, Robert, Venstrom, Kristy, Nellenbogen, Jean

“…Pulmonary surfactant is synthesized and secreted by alveolar type II cells. Radioactive phosphatidylcholine has been used as a marker for surfactant secretion…”
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Lung Surfactant Apoprotein SP-A (26-36 kDa) Binds with High Affinity to Isolated Alveolar Type II Cells by Wright, Jo Rae, Borchelt, Jenny D., Hawgood, Samuel

“…Pulmonary surfactant is synthesized and secreted by alveolar type II cells. These cells recycle surfactant lipids by an internalization process that is…”
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Effects of surfactant apolipoproteins on liposome structure: implications for tubular myelin formation by Poulain, F R, Allen, L, Williams, M C, Hamilton, R L, Hawgood, S

“…Tubular myelin is one of several forms of lung surfactant and may play an important role in its surface activity. To determine possible mechanisms of tubular…”
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