Search Results - "Hawasli, Ammar H."
-
1
Memory Enhancement by Targeting Cdk5 Regulation of NR2B
Published in Neuron (Cambridge, Mass.) (05-03-2014)“…Many psychiatric and neurological disorders are characterized by learning and memory deficits, for which cognitive enhancement is considered a valid treatment…”
Get full text
Journal Article -
2
An evidence-based treatment algorithm for the management of WHO Grade II and III meningiomas
Published in Neurosurgical focus (01-03-2015)“…The management of WHO Grade II "atypical" meningiomas (AMs) and Grade III "malignant" meningiomas (MMs) remains controversial and under-investigated in…”
Get full text
Journal Article -
3
Spinal Cord Injury Disrupts Resting-State Networks in the Human Brain
Published in Journal of neurotrauma (15-03-2018)“…Despite 253,000 spinal cord injury (SCI) patients in the United States, little is known about how SCI affects brain networks. Spinal MRI provides only…”
Get more information
Journal Article -
4
Extrasynaptic NMDA Receptors Couple Preferentially to Excitotoxicity via Calpain-Mediated Cleavage of STEP
Published in The Journal of neuroscience (22-07-2009)“…NMDA receptor (NMDAR)-mediated excitotoxicity plays an important role in several CNS disorders, including epilepsy, stroke, and ischemia. Here we demonstrate…”
Get full text
Journal Article -
5
Multi-modal biomarkers of low back pain: A machine learning approach
Published in NeuroImage clinical (01-01-2021)“…•Widespread differences in cortical thickness (CT) were observed in patients with low back pain.•Changes in CT correlated with self-reported clinical scores of…”
Get full text
Journal Article -
6
Functional Disruptions of the Brain in Low Back Pain: A Potential Imaging Biomarker of Functional Disability
Published in Frontiers in neurology (14-07-2021)“…Chronic low back pain (LBP) is one of the leading causes of disability worldwide. While LBP research has largely focused on the spine, many studies have…”
Get full text
Journal Article -
7
The role of resting state networks in focal neocortical seizures
Published in PloS one (23-09-2014)“…The role of resting state functional networks in epilepsy is incompletely understood. While some pathologic diagnoses have been shown to have maintained but…”
Get full text
Journal Article -
8
Cdk5 Modulates Cocaine Reward, Motivation, and Striatal Neuron Excitability
Published in The Journal of neuroscience (21-11-2007)“…Cyclin-dependent kinase 5 (Cdk5) regulates dopamine neurotransmission and has been suggested to serve as a homeostatic target of chronic psychostimulant…”
Get full text
Journal Article -
9
Influence of White and Gray Matter Connections on Endogenous Human Cortical Oscillations
Published in Frontiers in human neuroscience (28-06-2016)“…Brain oscillations reflect changes in electrical potentials summated across neuronal populations. Low- and high-frequency rhythms have different modulation…”
Get full text
Journal Article -
10
Magnetic Resonance Imaging-Guided Focused Laser Interstitial Thermal Therapy for Intracranial Lesions: Single-Institution Series
Published in Neurosurgery (01-12-2013)“…BACKGROUND:Surgical treatments for deep-seated intracranial lesions have been limited by morbidities associated with resection. Real-time magnetic resonance…”
Get full text
Journal Article -
11
Alternative roles for Cdk5 in learning and synaptic plasticity
Published in Biotechnology journal (01-08-2007)“…Protein kinases mediate the intracellular signal transduction pathways controlling synaptic plasticity in the central nervous system. While the majority of…”
Get full text
Journal Article -
12
Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5
Published in PloS one (04-06-2009)“…Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase that has been implicated in learning, synaptic plasticity, neurotransmission,…”
Get full text
Journal Article -
13
Minimally invasive transforaminal lumbar interbody fusion with expandable versus static interbody devices: radiographic assessment of sagittal segmental and pelvic parameters
Published in Neurosurgical focus (01-08-2017)“…OBJECTIVE Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) has been adopted as an alternative technique to hasten recovery and minimize…”
Get full text
Journal Article -
14
Resistance to Volatile Anesthetics by Mutations Enhancing Excitatory Neurotransmitter Release in Caenorhabditis elegans
Published in Genetics (Austin) (01-10-2004)“…The molecular mechanisms whereby volatile general anesthetics (VAs) disrupt behavior remain undefined. In Caenorhabditis elegans mutations in the gene unc-64,…”
Get full text
Journal Article -
15
Stereotactic laser ablation of high-grade gliomas
Published in Neurosurgical focus (01-12-2014)“…Evolving research has demonstrated that surgical cytoreduction of a high-grade glial neoplasm is an important factor in improving the prognosis of these…”
Get full text
Journal Article -
16
Treatment of sacroiliac joint laxity-induced coronal imbalance with the kickstand rod technique
Published in British journal of neurosurgery (01-12-2023)“…Considerations of the sacroiliac joint (SIJ) and its role in causing lower back and limb pain have taken a secondary role ever since Mixter and Barr's hallmark…”
Get full text
Journal Article -
17
Methods to Decrease Postoperative Infections Following Posterior Cervical Spine Surgery
Published in Journal of bone and joint surgery. American volume (20-03-2013)“…BACKGROUND:To decrease surgical site infections, we initiated a protocol of preliminary preparation of the skin and surrounding plastic drapes with alcohol…”
Get full text
Journal Article -
18
Patient-Reported Outcomes Measurement Information System physical function and pain interference in spine surgery
Published in Journal of neurosurgery. Spine (01-08-2019)“…The Patient-Reported Outcomes Measurement Information System (PROMIS) is an adaptive, self-reported outcomes assessment tool that utilizes item response theory…”
Get full text
Journal Article -
19
Idiopathic scoliosis and the vestibular system
Published in European spine journal (01-02-2015)“…Purpose Despite its high prevalence, the etiology underlying idiopathic scoliosis remains unclear. Although initial scrutiny has focused on genetic,…”
Get full text
Journal Article -
20
The role of laser interstitial thermal therapy in enhancing progression‐free survival of difficult‐to‐access high‐grade gliomas: a multicenter study
Published in Cancer medicine (Malden, MA) (01-08-2014)“…Surgical extent‐of‐resection has been shown to have an impact on high‐grade glioma (HGG) outcomes; however, complete resection is rarely achievable in…”
Get full text
Journal Article