Search Results - "Haverick, Mark"
-
1
Separation of mAbs molecular variants by analytical hydrophobic interaction chromatography HPLC: overview and applications
Published in mAbs (01-07-2014)“…Hydrophobic interaction chromatography-high performance liquid chromatography (HIC-HPLC) is a powerful analytical method used for the separation of molecular…”
Get full text
Journal Article -
2
Selective Plate-Based Assay for Trace EDTA Analysis via Boron Trifluoride-methanol Derivatization UHPLC-QqQ-MS/MS Enabling Biologic and Vaccine Processes
Published in Analytical chemistry (Washington) (25-01-2022)“…The employment of ethylenediaminetetraacetic acid (EDTA) across several fields in chemistry and biology has required the creation of a high number of…”
Get full text
Journal Article -
3
Multi-angle light scattering as a process analytical technology measuring real-time molecular weight for downstream process control
Published in mAbs (03-10-2018)“…For many protein therapeutics including monoclonal antibodies, aggregate removal process can be complex and challenging. We evaluated two different process…”
Get full text
Journal Article -
4
Fine-Tuning the pH Trigger of Self-Assembly
Published in Journal of the American Chemical Society (29-02-2012)“…The creation of smart, self-assembling materials that undergo morphological transitions in response to specific physiological environments can allow for the…”
Get full text
Journal Article -
5
Extensive Characterization of Polysorbate 80 Oxidative Degradation Under Stainless Steel Conditions
Published in Journal of pharmaceutical sciences (01-03-2023)“…Polysorbate-80 (PS-80) is a common surfactant used in biologics formulations. However, the tendency of oxidation to PS-80 when exposed to stainless steel…”
Get more information
Journal Article -
6
Effect of Pegylation on Self-Association of IFN-α2b
Published in Molecular pharmaceutics (06-01-2014)“…Pegylation of therapeutic proteins is an established technology used to enhance the bioavailability of an active pharmaceutical ingredient in the body of…”
Get full text
Journal Article