Search Results - "Havenga, Menzo"

Comparative Seroprevalence and Immunogenicity of Six Rare Serotype Recombinant Adenovirus Vaccine Vectors from Subgroups B and D by ABBINK, Peter, LEMCKERT, Angelique A. C, O'BRIEN, Kara L, CARVILLE, Angela, MANSFIELD, Keith G, GOUDSMIT, Jaap, HAVENGA, Menzo J. E, BAROUCH, Dan H, EWALD, Bonnie A, LYNCH, Diana M, DENHOLTZ, Matthew, SMITS, Shirley, HOLTERMAN, Lennart, DAMEN, Irma, VOGELS, Ronald, THORNER, Anna R

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Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity by Barouch, Dan H, Roberts, Diane M, Nanda, Anjali, Havenga, Menzo J. E, Abbink, Peter, Lynch, Diana M, Ewald, Bonnie A, Liu, Jinyan, Thorner, Anna R, Swanson, Patricia E, Gorgone, Darci A, Lifton, Michelle A, Lemckert, Angelique A. C, Holterman, Lennart, Chen, Bing, Dilraj, Athmanundh, Carville, Angela, Mansfield, Keith G, Goudsmit, Jaap

“…A common viral immune evasion strategy involves mutating viral surface proteins in order to evade host neutralizing antibodies. Such immune evasion tactics…”
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Neutralizing Antibodies to Adenovirus Serotype 5 Vaccine Vectors Are Directed Primarily against the Adenovirus Hexon Protein by Sumida, Shawn M, Truitt, Diana M, Lemckert, Angelique A. C, Vogels, Ronald, Custers, Jerome H. H. V, Addo, Marylyn M, Lockman, Shahin, Peter, Trevor, Peyerl, Fred W, Kishko, Michael G, Jackson, Shawn S, Gorgone, Darci A, Lifton, Michelle A, Essex, Myron, Walker, Bruce D, Goudsmit, Jaap, Havenga, Menzo J. E, Barouch, Dan H

“…The utility of recombinant adenovirus serotype 5 (rAd5) vector-based vaccines for HIV-1 and other pathogens will likely be limited by the high prevalence of…”
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Immunogenicity of Recombinant Adenovirus Serotype 35 Vaccine in the Presence of Pre-Existing Anti-Ad5 Immunity by Barouch, Dan H, Pau, Maria G, Custers, Jerome H. H. V, Koudstaal, Wouter, Kostense, Stefan, Havenga, Menzo J. E, Truitt, Diana M, Sumida, Shawn M, Kishko, Michael G, Arthur, Janelle C, Korioth-Schmitz, Birgit, Newberg, Michael H, Gorgone, Darci A, Lifton, Michelle A, Panicali, Dennis L, Nabel, Gary J, Letvin, Norman L, Goudsmit, Jaap

“…The high prevalence of pre-existing immunity to adenovirus serotype 5 (Ad5) in human populations may substantially limit the immunogenicity and clinical…”
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Trafficking of Antigen-Specific CD8+ T Lymphocytes to Mucosal Surfaces following Intramuscular Vaccination by Kaufman, David R, Liu, Jinyan, Carville, Angela, Mansfield, Keith G, Havenga, Menzo J. E, Goudsmit, Jaap, Barouch, Dan H

“…A critical goal of vaccine development for a wide variety of pathogens is the induction of potent and durable mucosal immunity. However, it has been assumed…”
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Age Dependence of Adenovirus-Specific Neutralizing Antibody Titers in Individuals from Sub-Saharan Africa by Thorner, Anna R, Vogels, Ronald, Kaspers, Jorn, Weverling, Gerrit J, Holterman, Lennart, Lemckert, Angelique A.C, Dilraj, Athmanundh, McNally, Lisa M, Jeena, Prakash M, Jepsen, Soren, Abbink, Peter, Nanda, Anjali, Swanson, Patricia E, Bates, Andrew T, O'Brien, Kara L, Havenga, Menzo J.E, Goudsmit, Jaap, Barouch, Dan H

“…We assessed neutralizing antibody titers to adenovirus serotype 5 (Ad5) and six rare adenovirus serotypes, serotypes 11, 35, 50, 26, 48, and 49, in pediatric…”
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Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer by PARKER, Alan L, WADDINGTON, Simon N, BUCKLEY, Suzanne M. K, CUSTERS, Jerome, HAVENGA, Menzo J. E, VAN ROOIJEN, Nico, GOUDSMIT, Jaap, MCVEY, John H, NICKLIN, Stuart A, BAKER, Andrew H

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Immunogenicity of Heterologous Prime-Boost Regimens Involving Recombinant Adenovirus Serotype 11 (Ad11) and Ad35 Vaccine Vectors in the Presence of Anti-Ad5 Immunity by LEMCKERT, Angelique A. C, SUMIDA, Shawn M, GOUDSMIT, Jaap, HAVENGA, Menzo J. E, BAROUCH, Dan H, HOLTERMAN, Lennart, VOGELS, Ronald, TRUITT, Diana M, LYNCH, Diana M, NANDA, Anjali, EWALD, Bonnie A, GORGONE, Darci A, LIFTON, Michelle A

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Species B adenovirus serotypes 3, 7, 11 and 35 share similar binding sites on the membrane cofactor protein CD46 receptor by Fleischli, Christoph, Sirena, Dominique, Lesage, Guillaume, Havenga, Menzo J. E, Cattaneo, Roberto, Greber, Urs F, Hemmi, Silvio

“…1 Institute of Molecular Biology, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland 2 Crucell Holland BV, Archimedesweg 4, 2333 CN…”
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Ex Vivo Expansion of Hematopoietic Stem Cells for Therapeutic Purposes: Lessons from Development and the Niche by Tajer, Parisa, Pike-Overzet, Karin, Arias, Sagrario, Havenga, Menzo, Staal, Frank J T

“…Expansion of hematopoietic stem cells (HSCs) for therapeutic purposes has been a "holy grail" in the field for many years. Ex vivo expansion of HSCs can help…”
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Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys by Barouch, Dan H, Liu, Jinyan, O'Brien, Kara L, Lynch, Diana M, Simmons, Nathaniel L, La Porte, Annalena, Riggs, Ambryice M, Abbink, Peter, Coffey, Rory T, Grandpre, Lauren E, Seaman, Michael S, Landucci, Gary, Forthal, Donald N, Montefiori, David C, Carville, Angela, Mansfield, Keith G, Havenga, Menzo J, Pau, Maria G, Goudsmit, Jaap

“…A recombinant adenovirus serotype 5 (rAd5) vector-based vaccine for HIV-1 has recently failed in a phase 2b efficacy study in humans. Consistent with these…”
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Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN by Adams, William C, Bond, Emily, Havenga, Menzo J. E, Holterman, Lennart, Goudsmit, Jaap, Karlsson Hedestam, Gunilla B, Koup, Richard A, Lore, Karin

“…1 Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden 2 The Swedish Institute for Infectious Disease Control,…”
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Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses by Loré, Karin, Adams, William C, Havenga, Menzo J E, Precopio, Melissa L, Holterman, Lennart, Goudsmit, Jaap, Koup, Richard A

“…Although replication-incompetent recombinant adenovirus (rAd) type 5 is a potent vaccine vector for stimulating T and B cell responses, high seroprevalence of…”
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Viral vectors for malaria vaccine development by Li, Shengqiang, Locke, Emily, Bruder, Joseph, Clarke, David, Doolan, Denise L, Havenga, Menzo J.E, Hill, Adrian V.S, Liljestrom, Peter, Monath, Thomas P, Naim, Hussein Y, Ockenhouse, Christian, Tang, De-chu C, Van Kampen, Kent R, Viret, Jean-Francois, Zavala, Fidel, Dubovsky, Filip

“…Abstract A workshop on viral vectors for malaria vaccine development, organized by the PATH Malaria Vaccine Initiative, was held in Bethesda, MD on October 20,…”
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Quantifying Adenovirus-Neutralizing Antibodies by Luciferase Transgene Detection: Addressing Preexisting Immunity to Vaccine and Gene Therapy Vectors by SPRANGERS, Mieke C, LAKHAI, Wandena, KOUDSTAAL, Wouter, VERHOEVEN, Marielle, KOEL, Björn F, VOGELS, Ronald, GOUDSMIT, Jaap, HAVENGA, Menzo J. E, KOSTENSE, Stefan

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Influence of Coagulation Factor Zymogens on the Infectivity of Adenoviruses Pseudotyped with Fibers from Subgroup D by PARKER, Alan L, MCVEY, John H, DOCTOR, Jessica H, LOPEZ-FRANCO, Oscar, WADDINGTON, Simon N, HAVENGA, Menzo J. E, NICKLIN, Stuart A, BAKER, Andrew H

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First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1 by Stephenson, Kathryn E, Keefer, Michael C, Bunce, Catherine A, Frances, Doreen, Abbink, Peter, Maxfield, Lori F, Neubauer, George H, Nkolola, Joseph, Peter, Lauren, Lane, Christopher, Park, Harriet, Verlinde, Carl, Lombardo, Angela, Yallop, Christopher, Havenga, Menzo, Fast, Patricia, Treanor, John, Barouch, Dan H

“…Live, attenuated viral vectors that express HIV-1 antigens are being investigated as an approach to generating durable immune responses against HIV-1 in…”
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Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity by Lemckert, Angelique A. C, Grimbergen, Jos, Smits, Shirley, Hartkoorn, Eric, Holterman, Lennart, Berkhout, Ben, Barouch, Dan H, Vogels, Ronald, Quax, Paul, Goudsmit, Jaap, Havenga, Menzo J. E

“…1 Crucell Holland BV, PO Box 2048, 2301 CA Leiden, The Netherlands 2 Gaubius Laboratory, TNO, 2301 CA Leiden, The Netherlands 3 Department of Human…”
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Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors by Abbink, Peter, Kirilova, Marinela, Boyd, Michael, Mercado, Noe, Li, Zhenfeng, Nityanandam, Ramya, Nanayakkara, Ovini, Peterson, Rebecca, Larocca, Rafael A, Aid, Malika, Tartaglia, Lawrence, Mutetwa, Tinaye, Blass, Eryn, Jetton, David, Maxfield, Lori F, Borducchi, Erica N, Badamchi-Zadeh, Alexander, Handley, Scott, Zhao, Guoyan, Virgin, Herbert W, Havenga, Menzo J, Barouch, Dan H

“…Human and chimpanzee adenovirus vectors are being developed to circumvent preexisting antibodies against common adenovirus vectors such as Ad5. However,…”
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A microbial expression system for high-level production of scFv HIV-neutralizing antibody fragments in Escherichia coli by Petrus, Marloes L. C., Kiefer, Lukas A., Puri, Pranav, Heemskerk, Evert, Seaman, Michael S., Barouch, Dan H., Arias, Sagrario, van Wezel, Gilles P., Havenga, Menzo

“…Monoclonal antibodies (mABs) are of great biopharmaceutical importance for the diagnosis and treatment of diseases. However, their production in mammalian…”
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