Search Results - "Havel, Richard"

Triglyceride-Rich Lipoproteins and Plasma Lipid Transport by Havel, Richard J

“…This memoir provides a history of the triglyceride-rich lipoproteins of blood plasma over the last half-century. As precursors of low-density lipoproteins and…”
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apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients by Pullinger, Clive R, Aouizerat, Bradley E, Movsesyan, Irina, Durlach, Vincent, Sijbrands, Eric J, Nakajima, Katsuyuki, Poon, Annie, Dallinga-Thie, Geesje M, Hattori, Hiroaki, Green, Lauri L, Kwok, Pui-Yan, Havel, Richard J, Frost, Philip H, Malloy, Mary J, Kane, John P

“…Apolipoprotein A-V (apoA-V) is an important regulator of plasma levels of triglyceride (TG) in mice. In humans, APOA5 genetic variation is associated with TG…”
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Rationale for Use of Non–High-Density Lipoprotein Cholesterol Rather Than Low-Density Lipoprotein Cholesterol as a Tool for Lipoprotein Cholesterol Screening and Assessment of Risk and Therapy by Frost, Philip H, Havel, Richard J

“…The plasma level of low-density lipoprotein (LDL) cholesterol is the “gold standard” for estimating the lipoprotein-related risk for complications of…”
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Hepatic Catabolism of Remnant Lipoproteins: Where the Action Is by Havel, Richard J, Hamilton, Robert L

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Introduction: John Gofman and the early years at the Donner Laboratory by Havel, Richard J., MD

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Management of Primary Hyperlipidemia by Havel, Richard J, Rapaport, Elliot

“…Epidemiologic, clinical, genetic, experimental, and pathological studies have clearly established the primary role of lipoproteins in atherogenesis. 1 , 2…”
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Tribute to Lew Gidez by Havel, Richard J

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Evaluation of an immunoseparation method for quantitative measurement of remnant-like particle-cholesterol in serum and plasma by Leary, Elizabeth Teng, Wang, Tao, Baker, Daniel J, Cilla, Donald D, Zhong, Jianhua, Warnick, G. Russell, Nakajima, Katsuyuki, Havel, Richard J

“…Substantial evidence indicates that triglyceride-rich lipoprotein remnants are atherogenic. Additional research has, however, been limited by available methods…”
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Regression of Coronary Atherosclerosis During Treatment of Familial Hypercholesterolemia With Combined Drug Regimens by Kane, John P, Malloy, Mary J, Ports, Thomas A, Phillips, Nancy R, Diehl, James C, Havel, Richard J

“…We conducted a randomized, controlled trial in 72 patients with heterozygous familial hypercholesterolemia to test whether reducing plasma low-density…”
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Endocytosis of Hepatic Lipase and Lipoprotein Lipase into Rat Liver Hepatocytes in Vivo Is Mediated by the Low Density Lipoprotein Receptor-related Protein by Vergés, Marcel, Bensadoun, Andre, Herz, Joachim, Belcher, John D., Havel, Richard J.

“…In isolated cell studies, the internalization and degradation of hepatic lipase (HL) has been linked to its binding to the low density lipoprotein…”
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Influence of Diets Rich in Saturated and Omega-6 Polyunsaturated Fatty Acids on the Postprandial Responses of Apolipoproteins B-48, B-100, E, and Lipids in Triglyceride-Rich Lipoproteins by Bergeron, Nathalie, Havel, Richard J

“…The effects of diets rich in saturated fatty acids (SFA) (total polyunsaturated fatty acids [PUFA] [g]/total SFA [g][P/S ratio], 0.2) or omega-6 PUFA (P/S…”
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Receptor and non-receptor mediated uptake of chylomicron remnants by the liver by HAVEL, R. J

“…The uptake of chylomicron remnants by rodent liver is mediated by proteins residing on the microvillous surface of hepatocytes and occurs in two steps. First,…”
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A Tubular Endosomal Fraction from Rat Liver: Biochemical Evidence of Receptor Sorting by Default by Verges, Marcel, Havel, Richard J., Mostov, Keith E.

“…We previously have isolated an endosomal fraction from rat liver, termed receptor-recycling compartment (RRC), which is highly enriched in recycling receptors…”
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Postprandial hyperlipidemia and remnant lipoproteins by Havel, R J

“…Improved methods for quantification of organ-specific contributions to postprandial hyperlipidemia indicate substantial increases in the concentration and…”
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Relationships between the responses of triglyceride-rich lipoproteins in blood plasma containing apolipoproteins B-48 and B-100 to a fat-containing meal in normolipidemic humans by Schneeman, Barbara O., Kotite, Leila, Todd, Karen M., Havel, Richard J.

“…The concentration of triglyceride-rich lipoproteins containing apolipoprotein (apo) B-48 (chylomicrons) and apo B-100 (very low density lipoproteins) was…”
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Properties of triglyceride-rich and cholesterol-rich lipoproteins in the remnant-like particle fraction of human blood plasma by Campos, Elisa, Kotite, Leila, Blanche, Patricia, Mitsugi, Yasushi, Frost, Philip H, Masharani, Umesh, Krauss, Ronald M, Havel, Richard J

“…An immunoassay procedure that quantifies remnant-like particle (RLP) cholesterol in human blood plasma has shown considerable promise as a clinically…”
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Genetic underpinnings of LDL size and density: a role for hepatic lipase? by Havel, R J

“…Plasma lipoprotein abnormalities underlie and may even be essential for the common occurrence of atherosclerotic vascular diseases in Western societies. The…”
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Clinical chemistry journal has contributed to progress in lipid and lipoprotein testing for fifty years by RIFAI, Nader, COOPER, Gerald R, BROWN, W. Virgil, FRIEDEWALD, William, HAVEL, Richard J, MYERS, Gary L, WARNICK, G. Russell

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Metabolism of lipoproteins containing apolipoprotein B in hepatic lipase-deficient mice by Qiu, S, Bergeron, N, Kotite, L, Krauss, R M, Bensadoun, A, Havel, R J

“…Mice lacking hepatic lipase have been reported to express mild hyperlipidemia characterized by increased concentrations of large high density lipoproteins, but…”
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Ratio of Remnant-like Particle-Cholesterol to Serum Total Triglycerides Is an Effective Alternative to Ultracentrifugal and Electrophoretic Methods in the Diagnosis of Familial Type III Hyperlipoproteinemia by Wang, Tao, Nakajima, Katsuyuki, Leary, Elizabeth Teng, Warnick, G. Russ, Cohn, Jeffrey S, Hopkins, Paul N, Wu, Lily L, Cilla, Donald D, Zhong, Jianhua, Havel, Richard J

“…Familial type III hyperlipoproteinemia (HLP) is characterized by the presence of beta-migrating VLDL (beta-VLDL) and increased risk of cardiovascular disease…”
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