Search Results - "Havarinasab, Said"

Exposure to Gold Induces Autoantibodies against Nuclear Antigens in A.TL Mice by Puente-Marin, Sara, Havarinasab, Said

“…To demonstrate causation or/and assess pathogenic mechanisms of environment-induced autoimmunity, various animal models that mimic the characteristics of the…”
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Bank1 and NF-kappaB as key regulators in anti-nucleolar antibody development by Alkaissi, Hammoudi, Havarinasab, Said, Nielsen, Jesper Bo, Söderkvist, Peter, Hultman, Per

“…Systemic autoimmune rheumatic disorders (SARD) represent important causes of morbidity and mortality in humans. The mechanisms triggering autoimmune responses…”
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HLA-DR7 and HLA-DQ2: Transgenic mouse strains tested as a model system for ximelagatran hepatotoxicity by Lundgren, Hanna, Martinsson, Klara, Cederbrant, Karin, Jirholt, Johan, Mucs, Daniel, Madeyski-Bengtson, Katja, Havarinasab, Said, Hultman, Per

“…The oral thrombin inhibitor ximelagatran was withdrawn in the late clinical trial phase because it adversely affected the liver. In approximately 8% of treated…”
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Determination of Methylmercury, Ethylmercury, and Inorganic Mercury in Mouse Tissues, Following Administration of Thimerosal, by Species-Specific Isotope Dilution GC−Inductively Coupled Plasma-MS by Qvarnström, Johanna, Lambertsson, Lars, Havarinasab, Said, Hultman, Per, Frech, Wolfgang

“…Isotopically enriched HgO standards were used to synthesize CH3 200Hg+ and C2H5 199Hg+ using Grignard reagents. These species were employed for isotope…”
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Secondary exposure to heavy metal in genetically susceptible mice leads to acceleration of autoimmune response by Puente-Marin, Sara, Hultman, Per, Ekstrand, Jimmy, Nielsen, Jesper Bo, Havarinasab, Said

“…Exposure to mercury (Hg) and silver (Ag) has been shown to induce autoimmune diseases in genetically susceptible rodents. Here, A.SW mice were initially…”
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Autoantibodies in outbred Swiss Webster mice following exposure to gold and mercury by Amirhosseini, Mehdi, Alkaissi, Hammoudi, Hultman, Per A., Havarinasab, Said

“…Exposure to heavy metals may have toxic effects on several human organs causing morbidity and mortality. Metals may trigger or exacerbate autoimmunity in…”
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Genome-Wide Association Study to Identify Genes Related to Renal Mercury Concentrations in Mice by Alkaissi, Hammoudi, Ekstrand, Jimmy, Jawad, Aksa, Nielsen, Jesper Bo, Havarinasab, Said, Soderkvist, Peter, Hultman, Per

“…Following human mercury (Hg) exposure, the metal accumulates in considerable concentrations in kidney, liver, and brain. Although the toxicokinetics of Hg have…”
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Organic mercury compounds and autoimmunity by Havarinasab, Said, Hultman, Per

“…Based on in vitro studies and short-term in vivo studies, all mercurials were for a long time considered as prototypic immunosuppressive substances. Recent…”
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Mercury toxicokinetics—dependency on strain and gender by Ekstrand, Jimmy, Nielsen, Jesper B., Havarinasab, Said, Zalups, Rudolfs K., Söderkvist, Peter, Hultman, Per

“…Mercury (Hg) exposure from dental amalgam fillings and thimerosal in vaccines is not a major health hazard, but adverse health effects cannot be ruled out in a…”
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Gold- and silver-induced murine autoimmunity - requirement for cytokines and CD28 in murine heavy metal-induced autoimmunity by Havarinasab, S, Pollard, K.M, Hultman, P

“…Treatment with gold in the form of aurothiomaleate, silver or mercury (Hg) in genetically susceptible mouse strains (H-2s) induces a systemic autoimmune…”
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The immunosuppressive effect of methylmercury does not preclude development of autoimmunity in genetically susceptible mice by Häggqvist, Bo, Havarinasab, Said, Björn, Erik, Hultman, Per

“…Methylmercury (MeHg) is a common environmental pollutant due to both natural and anthropogenic sources. Although the central nervous system (CNS) is considered…”
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Alteration of the spontaneous systemic autoimmune disease in (NZB × NZW)F1 mice by treatment with thimerosal (ethyl mercury) by Havarinasab, S., Hultman, P.

“…Inorganic mercury may aggravate murine systemic autoimmune diseases which are either spontaneous (genetically determined) or induced by non-genetic mechanisms…”
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Dose and Hg species determine the T-helper cell activation in murine autoimmunity by Havarinasab, Said, Björn, Erik, Ekstrand, Jimmy, Hultman, Per

“…Abstract Inorganic mercury (mercuric chloride—HgCl2 ) induces in mice an autoimmune syndrome (HgIA) with T cell-dependent polyclonal B cell activation and…”
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Mercury species in lymphoid and non-lymphoid tissues after exposure to methyl mercury: Correlation with autoimmune parameters during and after treatment in susceptible mice by Havarinasab, Said, Björn, Erik, Nielsen, Jesper B., Hultman, Per

“…Methylmercury (MeHg) is present in the environment as a result of the global cycling of mercury, although anthropogenic sources may dramatically increase the…”
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Gold causes genetically determined autoimmune and immunostimulatory responses in mice by Havarinasab, S., Johansson, U., Pollard, K. M., Hultman, P.

“…Summary Natrium aurothiomaleate (GSTM) is a useful disease‐modifying anti‐rheumatic drug, but causes a variety of immune‐mediated adverse effects in many…”
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Immunosuppressive and autoimmune effects of thimerosal in mice by Havarinasab, S., Häggqvist, B., Björn, E., Pollard, K.M., Hultman, P.

“…The possible health effects of the organic mercury compound thimerosal (ethylmercurithiosalicylate), which is rapidly metabolized to ethylmercury (EtHg), have…”
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Dose–response study of thimerosal-induced murine systemic autoimmunity by Havarinasab, S, Lambertsson, L, Qvarnström, J, Hultman, P

“…The organic compound ethylmercurithiosalicylate (thimerosal), which is primarily present in the tissues as ethylmercury, has caused illness and several deaths…”
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Determination of methylmercury, ethylmercury, and inorganic mercury in mouse tissues, following administration of thimerosal, by species-specific isotope dilution GC by Qvarnstrom, Johanna, Lambertsson, Lars, Havarinasab, Said, Hultman, Per, Frech, Wolfgang

“…Isotopically enriched HgO standards were used to synthesize CH320OHg+ and C2H5199Hg+ using Grignard reagents. These species were employed for isotope dilution…”
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Short- and long-term effects of T-cell modulating agents in experimental autoimmunity by Mellergård, Johan, Havarinasab, Said, Hultman, Per

“…Due to the easy and reliable induction of a disease condition with many of the features present in human autoimmunity, mercury-induced autoimmunity (mHgAI) in…”
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Effect of Thimerosal on the Murine Immune System - Especially Induction of Systemic Autoimmunity by Havarinasab, Said

“…The organic mercury compound ethylmercurithiosalicylate (thimerosal), an antiseptic and a preservative, has recently raised public health concern due to its…”
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