Search Results - "Haux, J"
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SOULMATE: the Swedish study of liver transplantation for isolated colorectal cancer liver metastases not suitable for operation or ablation, compared to best established treatment—a randomized controlled multicenter trial
Published in Current controlled trials in cardiovascular medicine (30-09-2022)“…Abstract Background Around one fourth of patients with colorectal cancer present themselves with distant metastases at the time of diagnosis, and one…”
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Digitoxin is a potential anticancer agent for several types of cancer
Published in Medical hypotheses (01-12-1999)“…The ability of digitalis to block cell proliferation has been well established for some time. Recently, digitalis in non-toxic concentrations has been showed…”
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ISO-005; An open-label, multiple-site, dose cohort, phase I/II study in patients with stage IV colorectal cancer
Published in European journal of cancer (1990) (01-02-2017)Get full text
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A phase I/II study of arfolitixorin and 5-fluorouracil in combination with oxaliplatin (plus or minus bevacizumab) or irinotecan in metastatic colorectal cancer
Published in ESMO open (01-10-2022)“…5-fluorouracil (5-FU) combined with a folate remains an essential treatment component for metastatic colorectal cancer (mCRC). Leucovorin is the folate most…”
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Digitalis; impinges on more than just the (ion-) pump
Published in Medical hypotheses (01-12-2002)“…Some forms of digitalis, such as digitoxin, inhibits proliferation and induces apoptosis in cancer cells in clinically relevant concentrations. Recently, it…”
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Specificity of Ethephon as a Butyrylcholinesterase Inhibitor and Phosphorylating Agent
Published in Chemical research in toxicology (01-12-2002)“…Butyrylcholinesterase (BChE) is inhibited by the plant growth regulator (2-chloroethyl)phosphonic acid (ethephon) as observed 25 years ago both in vitro and in…”
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Phosphobutyrylcholinesterase: Phosphorylation of the Esteratic Site of Butyrylcholinesterase by Ethephon [(2-Chloroethyl)phosphonic Acid] Dianion
Published in Chemical research in toxicology (01-07-2000)“…Ethephon [(2-chloroethyl)phosphonic acid] has two seemingly unrelated types of biological activity. It is a major agrochemical absorbed by crops, slowly…”
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491 - ISO-005; An open-label, multiple-site, dose cohort, phase I/II study in patients with stage IV colorectal cancer
Published in European journal of cancer (1990) (01-02-2017)Get full text
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Short-course neoadjuvant FOLFIRINOX versus upfront surgery for resectable pancreatic head cancer: A multicenter randomized phase-II trial (NORPACT-1)
Published in JOURNAL OF CLINICAL ONCOLOGY (10-06-2023)“…LBA4005 Background: Fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) has shown improved survival in metastatic pancreatic cancer, and…”
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Total neoadjuvant treatment using short-course radiotherapy and four CAPOX cycles in locally advanced rectal cancer with high-risk criteria for recurrence: a Swedish nationwide cohort study (LARCT-US)
Published in EClinicalMedicine (2024)“…Total neoadjuvant treatment (TNT) for locally advanced rectal cancer (LARC) increases pathologic complete response (pCR) rate and reduces the risk of systemic…”
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Lessons learned from a health record bank start-up
Published in Methods of information in medicine (2014)“…This article is part of a Focus Theme of METHODS of Information in Medicine on Health Record Banking. In late summer 2010, an organization was formed in…”
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Digitoxin medication and cancer; case control and internal dose-response studies
Published in BMC cancer (01-01-2001)“…Digitoxin induces apoptosis in different human malignant cell lines in vitro. In this paper we investigated if patients taking digitoxin for cardiac disease…”
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From Molecules to Patients: The Clinical Applications of Translational Bioinformatics
Published in Yearbook of medical informatics (13-08-2015)“…Objective: In order to realize the promise of personalized medicine, Translational Bioinformatics (TBI) research will need to continue to address…”
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Supporting translational research on inherited cardiomyopathies through information technology
Published in Methods of information in medicine (2013)“…The INHERITANCE project, funded by the European Commission, is aimed at studying genetic or inherited Dilated cardiomyopathies (DCM) and at understanding the…”
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Large-scale performance evaluation of e-homecare architectures using the WS-NS simulator
Published in Methods of information in medicine (2011)“…E-homecare creates opportunities to provide care faster, at lower cost and higher levels of convenience for patients. As e-homecare services are time-critical,…”
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Infection and cancer
Published in The Lancet (British edition) (14-07-2001)Get full text
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REGULATION OF APO-2 LIGAND/TRAIL EXPRESSION IN NK CELLS—INVOLVEMENT IN NK CELL-MEDIATED CYTOTOXICITY
Published in Cytokine (Philadelphia, Pa.) (01-09-1999)“…Apo-2L is a new member of the tumour necrosis factor (TNF) family shown to induce apoptosis in a number of tumour cell lines. Apo-2L mRNA is expressed by…”
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The dynamics of cell proliferation
Published in Medical hypotheses (01-01-2004)“…The article provides a mathematical description based on the theory of differential equations, for the proliferation of malignant cells (cancer). A model is…”
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