Search Results - "Hauwert, Niels J"

A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light by Gómez-Santacana, Xavier, de Munnik, Sabrina M, Mocking, Tamara A M, Hauwert, Niels J, Sun, Shanliang, Vijayachandran, Prashanna, de Esch, Iwan J P, Vischer, Henry F, Wijtmans, Maikel, Leurs, Rob

“…We report a detailed structure–activity relationship for the scaffold of VUF16216, a compound we have previously communicated as a small-molecule efficacy…”
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Optical control of the β2-adrenergic receptor with opto-prop-2: A cis-active azobenzene analog of propranolol by Bosma, Reggie, Dijon, Nicola C., Zheng, Yang, Schihada, Hannes, Hauwert, Niels J., Shi, Shuang, Arimont, Marta, Riemens, Rick, Custers, Hans, van de Stolpe, Andrea, Vischer, Henry F., Wijtmans, Maikel, Holliday, Nicholas D., Kuster, Diederik W.D., Leurs, Rob

“…In this study, we synthesized and evaluated new photoswitchable ligands for the beta-adrenergic receptors β1-AR and β2-AR, applying an azologization strategy…”
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A Photoswitchable Agonist for the Histamine H 3 Receptor, a Prototypic Family A G-Protein-Coupled Receptor by Hauwert, Niels J, Mocking, Tamara A M, Da Costa Pereira, Daniel, Lion, Ken, Huppelschoten, Yara, Vischer, Henry F, De Esch, Iwan J P, Wijtmans, Maikel, Leurs, Rob

“…Spatiotemporal control over biochemical signaling processes involving G protein-coupled receptors (GPCRs) is highly desired for dissecting their complex…”
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A Photoswitchable Agonist for the Histamine H3 Receptor, a Prototypic Family A G‐Protein‐Coupled Receptor by Hauwert, Niels J., Mocking, Tamara A. M., Da Costa Pereira, Daniel, Lion, Ken, Huppelschoten, Yara, Vischer, Henry F., De Esch, Iwan J. P., Wijtmans, Maikel, Leurs, Rob

“…Spatiotemporal control over biochemical signaling processes involving G protein‐coupled receptors (GPCRs) is highly desired for dissecting their complex…”
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Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology by Hauwert, Niels J, Mocking, Tamara A. M, Da Costa Pereira, Daniel, Kooistra, Albert J, Wijnen, Lisa M, Vreeker, Gerda C. M, Verweij, Eléonore W. E, De Boer, Albertus H, Smit, Martine J, De Graaf, Chris, Vischer, Henry F, de Esch, Iwan J. P, Wijtmans, Maikel, Leurs, Rob

“…Noninvasive methods to modulate G protein-coupled receptors (GPCRs) with temporal and spatial precision are in great demand. Photopharmacology uses photons to…”
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A Photoswitchable Agonist for the Histamine H3 Receptor, a Prototypic Family A G‐Protein‐Coupled Receptor by Hauwert, Niels J., Mocking, Tamara A. M., Da Costa Pereira, Daniel, Lion, Ken, Huppelschoten, Yara, Vischer, Henry F., De Esch, Iwan J. P., Wijtmans, Maikel, Leurs, Rob

“…Spatiotemporal control over biochemical signaling processes involving G protein‐coupled receptors (GPCRs) is highly desired for dissecting their complex…”
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A Photoswitchable Agonist for the Histamine H 3 Receptor, a Prototypic Family A G‐Protein‐Coupled Receptor by Hauwert, Niels J., Mocking, Tamara A. M., Da Costa Pereira, Daniel, Lion, Ken, Huppelschoten, Yara, Vischer, Henry F., De Esch, Iwan J. P., Wijtmans, Maikel, Leurs, Rob

“…Spatiotemporal control over biochemical signaling processes involving G protein‐coupled receptors (GPCRs) is highly desired for dissecting their complex…”
Get full text