Search Results - "Hauswirth, A."

Standards and standardization in mastocytosis: Consensus Statements on Diagnostics, Treatment Recommendations and Response Criteria by Valent, P., Akin, C., Escribano, L., Födinger, M., Hartmann, K., Brockow, K., Castells, M., Sperr, W. R., Kluin-Nelemans, H. C., Hamdy, N. A. T., Lortholary, O., Robyn, J., Van Doormaal, J., Sotlar, K., Hauswirth, A. W., Arock, M., Hermine, O., Hellmann, A., Triggiani, M., Niedoszytko, M., Schwartz, L. B., Orfao, A., Horny, H.-P., Metcalfe, D. D.

“…Although a classification for mastocytosis and diagnostic criteria are available, there remains a need to define standards for the application of diagnostic…”
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Ristocetin-induced platelet aggregation for monitoring of bleeding tendency in CLL treated with ibrutinib by Kazianka, L, Drucker, C, Skrabs, C, Thomas, W, Melchardt, T, Struve, S, Bergmann, M, Staber, P B, Porpaczy, E, Einberger, C, Heinz, M, Hauswirth, A, Raderer, M, Pabinger, I, Thalhammer, R, Egle, A, Wendtner, C-M, Follows, G, Hoermann, G, Quehenberger, P, Jilma, B, Jaeger, U

“…Bleeding because of impaired platelet function is a major side effect of the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib. We quantitatively assessed…”
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18F-fluoro-deoxy-glucose positron emission tomography (18F-FDG-PET) visualizes follicular lymphoma irrespective of grading by Wöhrer, S., Jaeger, U., Kletter, K., Becherer, A., Hauswirth, A., Turetschek, K., Raderer, M., Hoffmann, M.

“…Background: 18F-fluoro-deoxy-glucose positron emission tomography (18F-FDG-PET) has become a routine measure for staging and follow-up of patients with…”
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Expression of the target receptor CD33 in CD34+/CD38−/CD123+ AML stem cells by Hauswirth, A.W., Florian, S., Printz, D., Sotlar, K., Krauth, M.-T., Fritsch, G., Schernthaner, G.-H., Wacheck, V., Selzer, E., Sperr, W.R., Valent, P.

“…Background  CD33 (Siglec‐3) is becoming increasingly important as a target of antibody‐mediated therapy in acute myeloid leukaemia (AML). In normal…”
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Detection of differentiation‐ and activation‐linked cell surface antigens on cultured mast cell progenitors by Schernthaner, G.‐H., Hauswirth, A. W., Baghestanian, M., Agis, H., Ghannadan, M., Worda, C., Krauth, M.‐T., Printz, D., Fritsch, G., Sperr, W. R., Valent, P.

“…Background:  Mast cells (MC) are multifunctional effector cells of the immune system. They derive from uncommitted CD34+ hemopoietic progenitor cells (HPC)…”
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Detection of novel leukocyte differentiation antigens on basophils and mast cells by HLDA8 antibodies by Florian, S., Sonneck, K., Czerny, M., Hennersdorf, F., Hauswirth, A. W., Bühring, H.‐J., Valent, P.

“…Background:  Basophils (BA) and mast cells (MC) are important effector cells in allergic reactions. Development, growth and effector cell functions are…”
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Response to therapy with interferon alpha-2b and prednisolone in aggressive systemic mastocytosis: report of five cases and review of the literature by Hauswirth, Alexander W, Simonitsch-Klupp, Ingrid, Uffmann, Martin, Koller, Elisabeth, Sperr, Wolfgang R, Lechner, Klaus, Valent, Peter

“…Aggressive systemic mastocytosis (ASM) is a hematopoietic neoplasm characterized by infiltration of visceral organs by neoplastic mast cells (MCs) with…”
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Effects of various statins on cytokine‐dependent growth and IgE‐dependent release of histamine in human mast cells by Krauth, M. T., Majlesi, Y., Sonneck, K., Samorapoompichit, P., Ghannadan, M., Hauswirth, A. W., Baghestanian, M., Schernthaner, G. H., Worda, C., Müller, M. R., Sperr, W. R., Valent, P.

“…Background:  Statins are inhibitors of hydroxymethylglutaryl coenzyme A (HMG CoA) reductase, a key enzyme in mevalonic acid (MVA)‐dependent signaling. Recent…”
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Immunohistochemical assessment of CD25 is equally sensitive and diagnostic in mastocytosis compared to flow cytometry by Baumgartner, C., Sonneck, K., Krauth, M.-T., Kneidinger, M., Födinger, M., Hauswirth, A. W., Müllauer, L., Valent, P.

“…ABSTRACT Background   Systemic mastocytosis (SM) is a clonal myeloid disorder characterized by abnormal accumulation and growth of mast cells (MC) in internal…”
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Characterization of recombinant cat albumin by Reininger, R., Swoboda, I., Bohle, B., Hauswirth, A. W., Valent, P., Rumpold, H., Valenta, R., Spitzauer, S.

“…Summary Background  Indoor allergens derived from animals and mites often contribute to exacerbation of skin manifestations in atopic dermatitis (AD) patients…”
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Sequential gene expression profiling during treatment for identification of predictive markers and novel therapeutic targets in chronic lymphocytic leukemia by Shehata, M, Demirtas, D, Schnabl, S, Hilgarth, M, Hubmann, R, Fonatsch, C, Schwarzinger, I, Hopfinger, G, Eigenberger, K, Heintel, D, Porpaczy, E, Vanura, K, Hauswirth, A, Schwarzmeier, J D, Gaiger, A, Stilgenbauer, S, Hallek, M, Bilban, M, Jäger, U

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CD203c is overexpressed on neoplastic mast cells in systemic mastocytosis and is upregulated upon IgE receptor cross-linking by Hauswirth, A W, Escribano, L, Prados, A, Nuñez, R, Mirkina, I, Kneidinger, M, Florian, S, Sonneck, K, Vales, A, Schernthaner, G-H, Sanchez-Muñoz, L, Sperr, W R, Bühring, H-J, Orfao, A, Valent, P

“…The ectoenzyme E-NPP3 (CD203c) has recently been identified as a novel activation-linked cell surface antigen on basophils. In the present study, we examined…”
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Autoimmune thrombocytopenia in non-Hodgkin's lymphomas by Hauswirth, Alexander W, Skrabs, Cathrin, Schutzinger, Christian, Raderer, Markus, Chott, Andreas, Valent, Peter, Lechner, Klaus, Jager, Ulrich

“…1 Department of Medicine I, Division of Hematology and Hemostaseology and 2 Oncology 3 Department of Pathology, Medical University of Vienna, Vienna, Austria…”
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Human leukaemic stem cells: a novel target of therapy by Sperr, W. R., Hauswirth, A. W., Florian, S., Öhler, L., Geissler, K., Valent, P.

“…Acute myeloid leukaemia (AML) is a life‐threatening haematopoietic disease that is characterized by clonal growth and the accumulation of myelopoietic…”
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Interleukin-3 promotes the expression of E-NPP3/CD203C on human blood basophils in healthy subjects and in patients with birch pollen allergy by Hauswirth, A W, Sonneck, K, Florian, S, Krauth, M T, Bohm, A, Sperr, W R, Valenta, R, Schernthaner, G H, Printz, D, Fritsch, G, Buhring, H J, Valent, P

“…We recently identified the ectoenzyme CD203c as a novel basophil activation antigen that is upregulated in response to FcepsilonRI cross-linkage. We…”
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Recombinant allergens promote expression of aminopeptidase-n (CD13) on basophils in allergic patients by Sonneck, K, Baumgartner, C, Rebuzzi, L, Marth, K, Chen, K W, Hauswirth, A W, Florian, S, Vrtala, S, Bühring, H J, Valenta, R, Valent, P

“…IgE-dependent activation of basophils is associated with upregulation of several surface molecules. We recently identified the surface enzyme aminopeptidase N…”
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Detection of novel CD antigens on the surface of human mast cells and basophils by Ghannadan, Minoo, Hauswirth, Alexander W, Schernthaner, Gerit-Holger, Müller, Michael R, Klepetko, Walter, Schatzl, Georg, Sperr, Wolfgang R, Bühring, Hans-Jörg, Valent, Peter

“…Mast cells (MC) and basophils are effector cells of allergic reactions. Growth and function of these cells are regulated by a network of cytokines, other…”
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Cell surface membrane antigen phenotype of human gastrointestinal mast cells by Krauth, Maria-Theresa, Majlesi, Yasamin, Florian, Stefan, Bohm, Alexandra, Hauswirth, Alexander W, Ghannadan, Minoo, Wimazal, Friedrich, Raderer, Markus, Wrba, Friedrich, Valent, Peter

“…Mast cells (MC) are important effector cells of allergic and inflammatory reactions in diverse organs. These cells interact with a number of other immune cells…”
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Tryptase a Novel Biochemical Marker of Acute Myeloid Leukemia by Sperr, Wolfgang R., Hauswirth, Alexander W., Valent, Peter

“…Despite maturation arrest, blast cells in acute myeloid leukemia (AML) are often capable of expressing lineage-restricted (granulomonocytic or myelomastocytic)…”
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Quantitative, phenotypic, and functional evaluation of basophils in myelodysplastic syndromes by Füreder, W., Schernthaner, G.-H., Ghannadan, M., Hauswirth, A., Sperr, W. R., Semper, H., Majlesi, Y., Zwirner, J., Götze, O., Bühring, H.-J., Lechner, K., Valent, P.

“…Background The myelodysplastic syndromes (MDS) are a group of clonal haematological disorders characterized by cytopenia(s), reduced differentiation‐capacity…”
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