Search Results - "Hausmann, Ma"
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1
The long and winding road: from genetic risk factors to the understanding of disease-pathogenesis in Crohn’s disease
Published in Genes and immunity (01-11-2019)Get full text
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OGR1 Have Antagonistic Effects in Models of Colonic Inflammation
Published in International journal of molecular sciences (01-10-2023)“…G-protein-coupled receptors (GPRs), including pro-inflammatory ovarian cancer GPR1 (OGR1/GPR68) and anti-inflammatory T cell death-associated gene 8…”
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The proton-sensing receptors TDAG8 and GPR4 are differentially expressed in human and mouse oligodendrocytes: Exploring their role in neuroinflammation and multiple sclerosis
Published in PloS one (25-03-2024)“…Acidosis is one of the hallmarks of demyelinating central nervous system (CNS) lesions in multiple sclerosis (MS). The response to acidic pH is primarily…”
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Gp96 deficiency affects TLR4 functionality and impairs ERK and p38 phosphorylation
Published in PloS one (15-02-2018)“…Gp96 is an endoplasmic reticulum chaperone for multiple protein substrates. Its lack in intestinal macrophages of Crohn's disease (CD) patients is correlated…”
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Genotype-phenotype associations of polymorphisms within the gene locus of NOD-like receptor pyrin domain containing 3 in Swiss inflammatory bowel disease patients
Published in BMC gastroenterology (03-08-2021)“…Genetic variations within the regulatory region of the gene encoding NOD-like receptor pyrin domain containing 3 (NLRP3) have been associated with Crohn's…”
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HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats
Published in PloS one (30-06-2015)“…HLA-B27 is a common genetic risk factor for the development of Spondyloarthritides (SpA). HLA-B27 can misfold to form cell-surface heavy chain homodimers…”
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Regulation of the expression of chaperone gp96 in macrophages and dendritic cells
Published in PloS one (16-10-2013)“…The chaperone function of the ER-residing heat shock protein gp96 plays an important role in protein physiology and has additionally important immunological…”
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Expression of growth factor receptors and targeting of EGFR in cholangiocarcinoma cell lines
Published in BMC cancer (18-06-2010)“…Cholangiocarcinoma (CC) is a malignant neoplasm of the bile ducts or the gallbladder. Targeting of growth factor receptors showed therapeutic potential in…”
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