Search Results - "Hauk, Pricila"

A redox-based electrogenetic CRISPR system to connect with and control biological information networks by Bhokisham, Narendranath, VanArsdale, Eric, Stephens, Kristina T., Hauk, Pricila, Payne, Gregory F., Bentley, William E.

“…Electronic information can be transmitted to cells directly from microelectronics via electrode-activated redox mediators. These transmissions are decoded by…”
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Bacterial co-culture with cell signaling translator and growth controller modules for autonomously regulated culture composition by Stephens, Kristina, Pozo, Maria, Tsao, Chen-Yu, Hauk, Pricila, Bentley, William E.

“…Synthetic biology and metabolic engineering have expanded the possibilities for engineered cell-based systems. The addition of non-native biosynthetic and…”
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Engineering bacterial motility towards hydrogen-peroxide by Virgile, Chelsea, Hauk, Pricila, Wu, Hsuan-Chen, Shang, Wu, Tsao, Chen-Yu, Payne, Gregory F, Bentley, William E

“…Synthetic biologists construct innovative genetic/biological systems to treat environmental, energy, and health problems. Many systems employ rewired cells for…”
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In LipL32, the Major Leptospiral Lipoprotein, the C Terminus Is the Primary Immunogenic Domain and Mediates Interaction with Collagen IV and Plasma Fibronectin by Hauk, Pricila, Macedo, Felipe, Romero, Eliete Caló, Vasconcellos, Sílvio Arruda, de Morais, Zenaide Maria, Barbosa, Angela Silva, Ho, Paulo Lee

“…LipL32 is the major leptospiral outer membrane lipoprotein expressed during infection and is the immunodominant antigen recognized during the humoral immune…”
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Modification and Assembly of a Versatile Lactonase for Bacterial Quorum Quenching by Rhoads, Melissa K, Hauk, Pricila, Gupta, Valerie, Bookstaver, Michelle L, Stephens, Kristina, Payne, Gregory F, Bentley, William E

“…This work sets out to provide a self-assembled biopolymer capsule activated with a multi-functional enzyme for localized delivery. This enzyme, Pox, which is a…”
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Structure and Calcium-Binding Activity of LipL32, the Major Surface Antigen of Pathogenic Leptospira sp by Hauk, Pricila, Guzzo, Cristiane Rodrigues, Ramos, Henrique Roman, Ho, Paulo Lee, Farah, Chuck Shaker

“…Leptospirosis, a spirochaetal zoonotic disease caused by Leptospira, has been recognized as an important emerging infectious disease. LipL32 is the major…”
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A CRISPR-dCas9 System for Assaying and Selecting for RNase III Activity In Vivo in Escherichia coli by Hauk, Pricila, Weeks, Ryan, Ostermeier, Marc

“…Ribonuclease III (RNase III) and RNase III-like ribonucleases have a wide range of important functions and are found in all organisms, yet a simple and…”
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Plasmid-encoded protein attenuates E. coli swimming velocity and cell growth, not reprogrammed regulatory functions by Virgile, Chelsea, Hauk, Pricila, Wu, Hsuan-Chen, Bentley, William E.

“…In addition to engineering new pathways for synthesis, synthetic biologists rewire cells to carry out ‘programmable’ functions, an example being the creation…”
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Association of Frailty, Age, and Biological Sex With Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine–Induced Immunity in Older Adults by Shapiro, Janna R, Sitaras, Ioannis, Park, Han Sol, Aytenfisu, Tihitina Y, Caputo, Christopher, Li, Maggie, Lee, John, Johnston, Trevor S, Li, Huifen, Wouters, Camille, Hauk, Pricila, Jacobsen, Henning, Li, Yukang, Abrams, Engle, Yoon, Steve, Kocot, Andrew J, Yang, Tianrui, Huang, Yushu, Cramer, Steven M, Betenbaugh, Michael J, Debes, Amanda K, Morgan, Rosemary, Milstone, Aaron M, Karaba, Andrew H, Pekosz, Andrew, Leng, Sean X, Klein, Sabra L

“…Abstract Background Male sex and old age are risk factors for severe coronavirus disease 2019, but the intersection of sex and aging on antibody responses to…”
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Development of Cell-Based Sentinels for Nitric Oxide: Ensuring Marker Expression and Unimodality by McKay, Ryan, Hauk, Pricila, Quan, David, Bentley, William E

“…We generated “sentinel” bacteria that respond to the biomarker nitric oxide (NO) and produce a homogeneous and strong fluorescent response. Our dual-plasmid…”
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Plasmid‐encoded protein attenuates Escherichia coli swimming velocity and cell growth, not reprogrammed regulatory functions by Virgile, Chelsea, Hauk, Pricila, Wu, Hsuan‐Chen, Bentley, William E.

“…In addition to engineering new pathways for synthesis, synthetic biologists rewire cells to carry out “programmable” functions, an example being the creation…”
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Controlling localization of Escherichia coli populations using a two‐part synthetic motility circuit: An accelerator and brake by McKay, Ryan, Hauk, Pricila, Wu, Hsuan‐Chen, Pottash, Alex Eli, Shang, Wu, Terrell, Jessica, Payne, Gregory F., Bentley, William E.

“…Probiotics, whether taken as capsules or consumed in foods, have been regarded as safe for human use by regulatory agencies. Being living cells, they serve as…”
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Evidence of link between quorum sensing and sugar metabolism in Escherichia coli revealed via cocrystal structures of LsrK and HPr by Ha, Jung-Hye, Hauk, Pricila, Cho, Kun, Eo, Yumi, Ma, Xiaochu, Stephens, Kristina, Cha, Soyoung, Jeong, Migyeong, Suh, Jeong-Yong, Sintim, Herman O, Bentley, William E, Ryu, Kyoung-Seok

“…Quorum sensing (QS), a bacterial process that regulates population-scale behavior, is mediated by small signaling molecules, called autoinducers (AIs), that…”
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Insightful directed evolution of Escherichia coli quorum sensing promoter region of the lsrACDBFG operon: a tool for synthetic biology systems and protein expression by Hauk, Pricila, Stephens, Kristina, Mckay, Ryan, Virgile, Chelsea Ryan, Ueda, Hana, Ostermeier, Marc, Ryu, Kyoung-Seok, Sintim, Herman O, Bentley, William E

“…Quorum sensing (QS) regulates many natural phenotypes (e.q. virulence, biofilm formation, antibiotic resistance), and its components, when incorporated into…”
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Incorporating LsrK AI‐2 quorum quenching capability in a functionalized biopolymer capsule by Rhoads, Melissa K., Hauk, Pricila, Terrell, Jessica, Tsao, Chen‐Yu, Oh, Hyuntaek, Raghavan, Srinivasa R., Mansy, Sheref S., Payne, Gregory F., Bentley, William E.

“…Antibacterial resistance is an issue of increasing severity as current antibiotics are losing their effectiveness and fewer antibiotics are being developed…”
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Homologous Quorum Sensing Regulatory Circuit: A Dual-Input Genetic Controller for Modulating Quorum Sensing-Mediated Protein Expression in E. coli by Hauk, Pricila, Stephens, Kristina, Virgile, Chelsea, VanArsdale, Eric, Pottash, Alex Eli, Schardt, John S, Jay, Steven M, Sintim, Herman O, Bentley, William E

“…We developed a hybrid synthetic circuit that co-opts the genetic regulation of the native bacterial quorum sensing autoinducer-2 and imposes an extra external…”
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Model for the allosteric regulation of the Na+/Ca2+ exchanger NCX by Abiko, Layara Akemi, Vitale, Phelipe M., Favaro, Denize C., Hauk, Pricila, Li, Da-Wei, Yuan, Jiaqi, Bruschweiler-Li, Lei, Salinas, Roberto K., Brüschweiler, Rafael

“…ABSTRACT The Na+/Ca2+ exchanger provides a major Ca2+ extrusion pathway in excitable cells and plays a key role in the control of intracellular Ca2+…”
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Calcium Binding to Leptospira Outer Membrane Antigen LipL32 Is Not Necessary for Its Interaction with Plasma Fibronectin, Collagen Type IV, and Plasminogen by Hauk, Pricila, Barbosa, Angela Silva, Ho, Paulo Lee, Farah, Chuck Shaker

“…LipL32 is the most abundant outer membrane protein from pathogenic Leptospira and has been shown to bind extracellular matrix (ECM) proteins as well as Ca2+…”
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Model for the allosteric regulation of the N a + / C a 2+ exchanger NCX by Abiko, Layara Akemi, Vitale, Phelipe M., Favaro, Denize C., Hauk, Pricila, Li, Da‐Wei, Yuan, Jiaqi, Bruschweiler‐Li, Lei, Salinas, Roberto K., Brüschweiler, Rafael

“…ABSTRACT The Na + /Ca 2+ exchanger provides a major Ca 2+ extrusion pathway in excitable cells and plays a key role in the control of intracellular Ca 2+…”
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Model for the allosteric regulation of the Na super(+)/Ca super(2+) exchanger NCX by Abiko, Layara Akemi, Vitale, Phelipe M, Favaro, Denize C, Hauk, Pricila, Li, Da-Wei, Yuan, Jiaqi, Bruschweiler-Li, Lei, Salinas, Roberto K, Brueschweiler, Rafael

“…The Na super(+)/Ca super(2+) exchanger provides a major Ca super(2+) extrusion pathway in excitable cells and plays a key role in the control of intracellular…”
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