Search Results - "Haughney, Peter C."
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Complement inhibition in cynomolgus monkeys by anti-factor d antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration
Published in The Journal of pharmacology and experimental therapeutics (01-12-2014)“…Anti-factor D (AFD; FCFD4514S, lampalizumab) is a humanized IgG Fab fragment directed against factor D (fD), a rate-limiting serine protease in the alternative…”
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A human prostatic epithelial model of hormonal carcinogenesis
Published in Cancer research (Chicago, Ill.) (15-08-2001)“…The effects of stromal and hormonal environment on the immortalized but nontumorigenic human prostatic epithelial cell line BPH-1 were investigated in an in…”
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Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model
Published in Differentiation (London) (01-07-1998)“…Tissue recombinants composed of adult human prostatic epithelium (hPrE) and rat urogenital sinus mesenchyme (rUGM) were grafted beneath the renal capsule of…”
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Species-Specific Detection of Growth Factor Gene Expression in Developing Murine Prostatic Tissue
Published in Biology of reproduction (01-07-1998)“…The aim of the present study was to develop a method by which the expression of paracrine signaling molecules could be localized to either epithelial or…”
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Abstract 5551: SGN-2FF: A small-molecule inhibitor of fucosylation modulates immune cell activity in preclinical models and demonstrates pharmacodynamic activity in early phase 1 analysis
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…SGN-2FF, an orally bioavailable small molecule inhibitor of glycoprotein fucosylation, demonstrates encouraging preclinical antitumor activity in mouse models…”
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The rat prostatic epithelial cell line NRP-152 can differentiate in vivo in response to its stromal environment
Published in The Prostate (15-05-1999)“…BACKGROUND The clonally derived rat prostatic epithelial cell line NRP‐152 was examined to determine its ability to differentiate in a tissue recombination…”
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Differential gene expression of transforming growth factors alpha and beta, epidermal growth factor, keratinocyte growth factor and their receptors in fetal and adult human prostatic tissues and cancer cell lines
Published in Urology (Ridgewood, N.J.) (01-12-1996)“…Recent studies have shown that growth factors may play a role in the etiology of benign prostatic hyperplasia (BPH) and prostatic carcinoma. Several growth…”
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Species-Specific Detection of Growth Factor Gene Expression in Developing Murine Prostatic Tissue1
Published in Biology of reproduction (01-07-1998)Get full text
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Terms and techniques: New approach to hot-start polymerase chain reaction using Taq DNA polymerase antibody
Published in Urologic oncology (1995)“…The purpose of this study was to optimize the conditions for polymerase chain reaction (PCR). The most common problem with conventional PCR is the presence of…”
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