Search Results - "Haug, Terje"
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1
In Vitro Expansion of Human Mesenchymal Stem Cells: Choice of Serum Is a Determinant of Cell Proliferation, Differentiation, Gene Expression, and Transcriptome Stability
Published in Stem cells (Dayton, Ohio) (01-10-2005)“…Human bone marrow mesenchymal stem cells (hMSCs) represent an appealing source of adult stem cells for cell therapy and tissue engineering, as they are easily…”
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2
A Sequence in the N-terminal Region of Human Uracil-DNA Glycosylase with Homology to XPA Interacts with the C-terminal Part of the 34-kDa Subunit of Replication Protein A
Published in The Journal of biological chemistry (07-03-1997)“…Uracil-DNA glycosylase releases free uracil from DNA and initiates base excision repair for removal of this potentially mutagenic DNA lesion. Using the yeast…”
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3
Comparison of gene expression in HCT116 treatment derivatives generated by two different 5-fluorouracil exposure protocols
Published in Molecular cancer (26-04-2004)“…Established colorectal cancer cell lines subjected to different 5-fluorouracil (5-FU) treatment protocols are often used as in vitro model systems for…”
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4
Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice
Published in Free radical research (2007)“…DNA repair may prevent increased levels of oxidatively damaged DNA from prolonged oxidative stress induced by, e.g. exposure to diesel exhaust particles (DEP)…”
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5
Increased expression of interleukin-1 in coronary artery disease with downregulatory effects of HMG-CoA reductase inhibitors
Published in Circulation (New York, N.Y.) (27-04-2004)“…Inflammation is important in atherogenesis. Interleukin (IL)-1 is the prototypic inflammatory cytokine. We hypothesized a dysbalance between inflammatory and…”
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Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites
Published in The EMBO journal (15-10-1997)“…The guanine modification 7,8‐dihydro‐8‐oxoguanine (8‐oxoG) is a potent premutagenic lesion formed spontaneously at high frequencies in the genomes of aerobic…”
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7
Post-replicative base excision repair in replication foci
Published in The EMBO journal (01-07-1999)“…Base excision repair (BER) is initiated by a DNA glycosylase and is completed by alternative routes, one of which requires proliferating cell nuclear antigen…”
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Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
Published in Nucleic acids research (15-02-1997)“…A distinct nuclear form of human uracil-DNA glycosylase [UNG2, open reading frame (ORF) 313 amino acid residues] from the UNG gene has been identified. UNG2…”
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9
Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil
Published in International journal of oncology (01-05-2004)“…5-Fluorouracil (5-FU) is the chemotherapeutic drug of choice for the treatment of metastatic colorectal cancer, but resistance to 5-FU remains a major obstacle…”
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10
Macrophage enrichment from induced sputum
Published in Thorax (01-06-2007)Get full text
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11
Increased gene expression of tumor necrosis factor superfamily ligands in peripheral blood mononuclear cells during chronic heart failure
Published in Cardiovascular research (01-04-2002)“…Inflammation may play a pathogenic role in chronic heart failure (CHF). The objective of the study was to characterise the imbalance in the cytokine network in…”
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12
Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase
Published in Biochemistry (Easton) (10-01-1995)“…We have expressed a human recombinant uracil-DNA glycosylase (UNG delta 84) closely resembling the mature form of the human enzyme (UNG, from the UNG gene) in…”
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13
Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively
Published in Nucleic acids research (15-10-1998)“…Nuclear (UNG2) and mitochondrial (UNG1) forms of human uracil-DNA glycosylase are both encoded by the UNG gene but have different N-terminal sequences. We have…”
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14
DNA transfection of mononuclear cells in muscle tissue
Published in The journal of gene medicine (01-10-2003)“…Background Genes encoding non‐self proteins may be injected into skeletal muscles in vivo to obtain induction of cellular and humoral immune responses against…”
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15
Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase
Published in Nucleic acids research (15-03-1998)“…Promoters PA and PB in the UNG gene and alternative splicing are utilized to generate nuclear (UNG2) and mitochondrial (UNG1) forms of human uracil-DNA…”
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16
Airway Inflammation in Paper Mill Workers
Published in Journal of occupational and environmental medicine (01-10-2007)“…Paper mill workers are exposed to culturable microorganisms (MOs). We hypothesized that inflammatory airway response could be detected in sputum of…”
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17
RAMP2 and RAMP3 mRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin
Published in Journal of molecular and cellular cardiology (2005)“…Adrenomedullin (AM) is a potent vasorelaxing peptide with natriuretic and diuretic actions. Recent data indicate that AM may function as an endogenous…”
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18
Myocardial gene expression of inflammatory cytokines after heart transplantation in relation to the development of transplant coronary artery disease
Published in The American journal of cardiology (15-09-2003)“…Long-term success of cardiac transplantation is mainly limited by the development of transplant coronary artery disease (CAD); it is generally accepted that it…”
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19
Public health and air pollution
Published in The Lancet (British edition) (2001)Get full text
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20
Exposure to culturable microorganisms in paper mills and presence of symptoms associated with infections
Published in American journal of industrial medicine (01-06-2002)“…Background Previous studies of paper machine operators have to a large extent focused on endotoxins as a possible health hazard, but not culturable…”
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