Search Results - "Hauer, Michael H."

Chromatin and nucleosome dynamics in DNA damage and repair by Hauer, Michael H, Gasser, Susan M

“…Chromatin is organized into higher-order structures that form subcompartments in interphase nuclei. Different categories of specialized enzymes act on…”
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Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos by Gonzalez-Sandoval, Adriana, Towbin, Benjamin D., Kalck, Veronique, Cabianca, Daphne S., Gaidatzis, Dimos, Hauer, Michael H., Geng, Liqing, Wang, Li, Yang, Teddy, Wang, Xinghao, Zhao, Kehao, Gasser, Susan M.

“…Interphase chromatin is organized in distinct nuclear sub-compartments, reflecting its degree of compaction and transcriptional status. In Caenorhabditis…”
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SWR1 and INO80 Chromatin Remodelers Contribute to DNA Double-Strand Break Perinuclear Anchorage Site Choice by Horigome, Chihiro, Oma, Yukako, Konishi, Tatsunori, Schmid, Roger, Marcomini, Isabella, Hauer, Michael H., Dion, Vincent, Harata, Masahiko, Gasser, Susan M.

“…Persistent DNA double-strand breaks (DSBs) are recruited to the nuclear periphery in budding yeast. Both the Nup84 pore subcomplex and Mps3, an inner nuclear…”
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Chromosome Dynamics in Response to DNA Damage by Seeber, Andrew, Hauer, Michael H, Gasser, Susan M

“…Recent advances in both the technologies used to measure chromatin movement and the biophysical analysis used to model them have yielded a fuller understanding…”
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Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair by Challa, Kiran, Schmid, Christoph D., Kitagawa, Saho, Cheblal, Anaïs, Iesmantavicius, Vytautas, Seeber, Andrew, Amitai, Assaf, Seebacher, Jan, Hauer, Michael H., Shimada, Kenji, Gasser, Susan M.

“…Eukaryotic cells package their genomes around histone octamers. In response to DNA damage, checkpoint activation in yeast induces core histone degradation…”
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Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates by Hauer, Michael H, Seeber, Andrew, Singh, Vijender, Thierry, Raphael, Sack, Ragna, Amitai, Assaf, Kryzhanovska, Mariya, Eglinger, Jan, Holcman, David, Owen-Hughes, Tom, Gasser, Susan M

“…A combination of SILAC-MS, genome-wide nucleosome mapping and live-cell imaging reveal rapid histone degradation and global chromatin decompaction after the…”
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INO80-C and SWR-C: Guardians of the Genome by Gerhold, Christian-Benedikt, Hauer, Michael H., Gasser, Susan M.

“…The double membrane of the eukaryotic nucleus surrounds the genome, constraining it to a nuclear sphere. Proteins, RNA protein particles and artificial…”
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Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model by Harr, Jennifer C, Schmid, Christoph D, Muñoz-Jiménez, Celia, Romero-Bueno, Raquel, Kalck, Véronique, Gonzalez-Sandoval, Adriana, Hauer, Michael H, Padeken, Jan, Askjaer, Peter, Mattout, Anna, Gasser, Susan M

“…Mutations in the nuclear structural protein lamin A produce rare, tissue-specific diseases called laminopathies. The introduction of a human Emery-Dreifuss…”
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