Search Results - "Hauck, S. M."
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Osteopontin inhibits osmotic swelling of retinal glial (Müller) cells by inducing release of VEGF
Published in Neuroscience (29-08-2013)“…Highlights • Osteopontin inhibits osmotic swelling of retinal glial cells. • Osteopontin does not inhibit osmotic swelling of bipolar cells. • Osteopontin…”
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True blue: S‐opsin is widely expressed in different animal species
Published in Journal of animal physiology and animal nutrition (01-02-2014)“…Colour vision in animals is an interesting, fascinating subject. In this study, we examined a wide variety of species for expression of S‐opsin (blue…”
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Isolation, characterization and establishment of an equine retinal glial cell line: a prerequisite to investigate the physiological function of Müller cells in the retina
Published in Journal of animal physiology and animal nutrition (01-04-2012)“…Retinal Müller glial cells are of vital importance for maintaining a physiological environment within the retina. To this end, they provide highly specialized…”
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Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas
Published in Oncogene (11-08-2016)“…Constitutive activation of the antiapoptotic nuclear factor-κB (NF-κB) signaling pathway is a hallmark of the activated B-cell-like (ABC) subtype of diffuse…”
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The hand eczema proteome: imbalance of epidermal barrier proteins
Published in British journal of dermatology (1951) (01-04-2015)“…Summary Background Chronic hand eczema (CHE) is a common skin disease with a high socioeconomic impact. While some light has been shed on the genetic factors…”
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Investigation of corneal autoantibodies in horses with immune mediated keratitis (IMMK)
Published in Veterinary immunology and immunopathology (01-05-2017)“…Immune mediated keratitis (IMMK) is primarily a non-ulcerative keratitis in horses causing intermittent ocular pain, eventually resulting in visual impairment…”
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Therapeutic targeting of naturally presented myeloperoxidase-derived HLA peptide ligands on myeloid leukemia cells by TCR-transgenic T cells
Published in Leukemia (01-12-2014)“…T cells have been proven to be therapeutically effective in patients with relapsed leukemias, although target antigens on leukemic cells as well as T-cell…”
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In situ cell surface proteomics reveals differentially expressed membrane proteins in retinal pigment epithelial cells during autoimmune uveitis
Published in Journal of proteomics (23-09-2014)“…Retinal pigment epithelium (RPE) builds the outer blood–retinal barrier of the eye and plays an important role in pathogenesis of the sight threatening disease…”
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A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies
Published in Histochemistry and cell biology (01-10-2014)“…The aim of this study was to establish an ex vivo model for a faster optimisation of sample preparation procedures, for example matrix choice, in…”
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A common atopy‐associated variant in the Th2 cytokine locus control region impacts transcriptional regulation and alters SMAD3 and SP1 binding
Published in Allergy (Copenhagen) (01-05-2014)“…Background Type 2 immune responses directed by Th2 cells and characterized by the signature cytokines IL4, IL5, and IL13 play major pathogenic roles in atopic…”
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Follow-up protein profiles in urine samples during the course of obstructive feline idiopathic cystitis
Published in The veterinary journal (1997) (01-12-2013)“…Feline idiopathic cystitis (FIC) is a common lower urinary tract disorder in cats, which often recurs. Published reports document increased urine fibronectin…”
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High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice
Published in Molecular metabolism (Germany) (01-01-2015)“…Abstract Objective Excess lipid intake has been implicated in the pathophysiology of hepatosteatosis and hepatic insulin resistance. Lipids constitute…”
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Feasibility and quality development of biomaterials in the pretest studies of the German National Cohort
Published in Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz (01-11-2014)“…Background The German National Cohort (GNC) is designed to address research questions concerning a wide range of possible causes of major chronic diseases…”
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Defining Cytochemical Markers for Different Cell Types in the Equine Retina
Published in Anatomia, histologia, embryologia (01-12-2006)“…Summary The major cell types in the mammalian retina are photoreceptors, amacrine, horizontal, bipolar, ganglion and Mueller glial cells. Most of the specific…”
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Plasma proteomics of all-cause and cause-specific mortality in individuals with and without type 2 diabetes: Results from two population-based KORA cohorts
Published in European heart journal (28-10-2024)“…Abstract Background Protein biomarkers may contribute to the identification of vulnerable subgroups for premature mortality in middle-aged and older adults…”
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Deciphering the Plasma Proteome of Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-12-2020)“…With an estimated prevalence of 463 million affected, type 2 diabetes represents a major challenge to health care systems worldwide. Analyzing the plasma…”
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The centrosome protein AKNA regulates neurogenesis via microtubule organization
Published in Nature (London) (01-03-2019)“…The expansion of brain size is accompanied by a relative enlargement of the subventricular zone during development. Epithelial-like neural stem cells divide in…”
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Serum protein identification and quantification of the corona of 5, 15 and 80 nm gold nanoparticles
Published in Nanotechnology (05-07-2013)“…When nanoparticles (NP) enter the body they come into contact with body fluids containing proteins which can adsorb to their surface. These proteins may…”
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A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases
Published in EBioMedicine (01-03-2023)“…A major evolution from purely clinical diagnoses to biomarker supported clinical diagnosing has been occurring over the past years in neurology…”
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