Search Results - "Haubein, Ned"

Categorical meta-analysis of Osteopontin as a clinical cancer marker by WEBER, Georg F, LETT, G. Scott, HAUBEIN, Ned C

“…Although extensive literature exists on cancer biomarkers few have found entry into clinical use. In particular, the cancer metastasis gene Osteopontin has…”
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Quantum Chemical Investigation of the Koch Carbonylation of Methyl tert-Butyl Ether (MTBE) by Haubein, Ned C, Broadbelt, Linda J, Schlosberg, Richard H

“…Methyl tert-butyl ether (MTBE) is a widely used additive in oxygenated gasoline that has recently come under environmental pressure. Consequently, the demand…”
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Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection by Painter, Mark M., Johnston, Timothy S., Lundgreen, Kendall A., Santos, Jefferson J. S., Qin, Juliana S., Goel, Rishi R., Apostolidis, Sokratis A., Mathew, Divij, Fulmer, Bria, Williams, Justine C., McKeague, Michelle L., Pattekar, Ajinkya, Goode, Ahmad, Nasta, Sean, Baxter, Amy E., Giles, Josephine R., Skelly, Ashwin N., Felley, Laura E., McLaughlin, Maura, Weaver, Joellen, Kuthuru, Oliva, Dougherty, Jeanette, Adamski, Sharon, Long, Sherea, Kee, Macy, Clendenin, Cynthia, da Silva Antunes, Ricardo, Grifoni, Alba, Weiskopf, Daniela, Sette, Alessandro, Huang, Alexander C., Rader, Daniel J., Hensley, Scott E., Bates, Paul, Greenplate, Allison R., Wherry, E. John

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of vaccinated individuals is increasingly common but rarely results in severe disease,…”
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A deep catalogue of protein-coding variation in 983,578 individuals by Sun, Kathie Y., Bai, Xiaodong, Chen, Siying, Bao, Suying, Zhang, Chuanyi, Kapoor, Manav, Backman, Joshua, Joseph, Tyler, Maxwell, Evan, Mitra, George, Gorovits, Alexander, Mansfield, Adam, Boutkov, Boris, Gokhale, Sujit, Habegger, Lukas, Marcketta, Anthony, Locke, Adam E., Ganel, Liron, Hawes, Alicia, Kessler, Michael D., Sharma, Deepika, Staples, Jeffrey, Bovijn, Jonas, Gelfman, Sahar, Di Gioia, Alessandro, Rajagopal, Veera M., Lopez, Alexander, Varela, Jennifer Rico, Alegre-Díaz, Jesús, Berumen, Jaime, Tapia-Conyer, Roberto, Kuri-Morales, Pablo, Torres, Jason, Emberson, Jonathan, Collins, Rory, Cantor, Michael, Thornton, Timothy, Kang, Hyun Min, Overton, John D., Shuldiner, Alan R., Cremona, M. Laura, Nafde, Mona, Baras, Aris, Abecasis, Gonçalo, Marchini, Jonathan, Reid, Jeffrey G., Salerno, William, Balasubramanian, Suganthi

“…Rare coding variants that substantially affect function provide insights into the biology of a gene 1 – 3 . However, ascertaining the frequency of such…”
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Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone by Dunn, Michael E., Kithcart, Aaron, Kim, Jee Hae, Ho, Andre Jo-Hao, Franklin, Matthew C., Romero Hernandez, Annabel, de Hoon, Jan, Botermans, Wouter, Meyer, Jonathan, Jin, Ximei, Zhang, Dongqin, Torello, Justin, Jasewicz, Daniel, Kamat, Vishal, Garnova, Elena, Liu, Nina, Rosconi, Michael, Pan, Hao, Karnik, Satyajit, Burczynski, Michael E., Zheng, Wenjun, Rafique, Ashique, Nielsen, Jonas B., De, Tanima, Verweij, Niek, Pandit, Anita, Locke, Adam, Chalasani, Naga, Melander, Olle, Schwantes-An, Tae-Hwi, Baras, Aris, Lotta, Luca A., Musser, Bret J., Mastaitis, Jason, Devalaraja-Narashimha, Kishor B., Rankin, Andrew J., Huang, Tammy, Herman, Gary, Olson, William, Murphy, Andrew J., Yancopoulos, George D., Olenchock, Benjamin A., Morton, Lori

“…Heart failure is a leading cause of morbidity and mortality 1 , 2 . Elevated intracardiac pressures and myocyte stretch in heart failure trigger the release of…”
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CT imaging-derived phenotypes for abdominal muscle and their association with age and sex in a medical biobank by Vu, Phuong T., Chahine, Chantal, Chatterjee, Neil, MacLean, Matthew T., Swago, Sophia, Bhattaru, Abhi, Thompson, Elizabeth W., Ikhlas, Anooshey, Oteng, Edith, Davidson, Lauren, Tran, Richard, Hazim, Mohamad, Raghupathy, Pavan, Verma, Anurag, Duda, Jeffrey, Gee, James, Luks, Valerie, Gershuni, Victoria, Wu, Gary, Rader, Daniel, Sagreiya, Hersh, Witschey, Walter R.

“…The study of muscle mass as an imaging-derived phenotype (IDP) may yield new insights into determining the normal and pathologic variations in muscle mass in…”
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Clinical correlates of CT imaging-derived phenotypes among lean and overweight patients with hepatic steatosis by Song, Isabel, Thompson, Elizabeth W., Verma, Anurag, MacLean, Matthew T., Duda, Jeffrey, Elahi, Ameena, Tran, Richard, Raghupathy, Pavan, Swago, Sophia, Hazim, Mohamad, Bhattaru, Abhijit, Schneider, Carolin, Vujkovic, Marijana, Torigian, Drew A., Kahn, Charles E., Gee, James C., Borthakur, Arijitt, Kripke, Colleen M., Carson, Christopher C., Carr, Rotonya, Jehangir, Qasim, Ko, Yi-An, Litt, Harold, Rosen, Mark, Mankoff, David A., Schnall, Mitchell D., Shou, Haochang, Chirinos, Julio, Damrauer, Scott M., Serper, Marina, Chen, Jinbo, Rader, Daniel J., Witschey, Walter R. T., Sagreiya, Hersh

“…The objective of this study is to define CT imaging derived phenotypes for patients with hepatic steatosis, a common metabolic liver condition, and determine…”
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Polygenic risk score-based phenome-wide association for glaucoma and its impact on disease susceptibility in two large biobanks by Yun, Jae-Seung, Jung, Sang-Hyuk, Lee, Su-Nam, Jung, Seung Min, Won, Hong-Hee, Kim, Dokyoon, Choi, Jin A

“…Glaucoma is a leading cause of worldwide irreversible blindness. Considerable uncertainty remains regarding the association between a variety of phenotypes and…”
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Many-Body Optimization Using an Ab Initio Monte Carlo Method by Haubein, Ned C, McMillan, Scott A, Broadbelt, Linda J

“…Advances in computing power have made it possible to study solvated molecules using ab initio quantum chemistry. Inclusion of discrete solvent molecules is…”
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Ab Initio Stochastic Optimization of Conformational and Many-Body Degrees of Freedom by McMillan, Scott A, Haubein, Ned C, Snurr, Randall Q, Broadbelt, Linda J

“…Moderate to large size molecules in solution have complex energy surfaces due to intramolecular (conformational) and intermolecular (many-body) interactions…”
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PMS2CL interference leading to erroneous identification of a pathogenic PMS2 variant in Black patients by Cappadocia, Jacqueline, Aiello, Lisa B., Kelley, Michael J., Katona, Bryson W., Verma, Anurag, Brock, Ashlei, DerOhannessian, Stephanie, Dudek, Scott, Drivas, Theodore, Haubein, Ned, Hu-Sain, Khadijah, Judy, Renae, Ko, Yi-An, Livingstone, Meghan, Morrel, Linda, Morse, Colleen, Risman, Marjorie, Tran, Teo, Vadivieso, Fred, Weaver, JoEllen, Rader, Daniel J., Ritchie, Marylyn D., Feldman, Michael D., Beechert, Christina, Fuller, Erin D., Lopez, Alexander, Overton, John D., Padilla, Maria Sotiropoulos, Manoochehri, Kia, Schleicher, Thomas D., Widom, Louis, Wolf, Sarah E., Banerjee, Nilanjana, Cantor, Michael, Li, Dadong, Malhotra, Sameer, Sharma, Deepika, Staples, Jeffrey, Bai, Xiaodong, Bao, Suying, Eom, Gisu, Habegger, Lukas, Hawes, Alicia, Lanche, Rouel, Mansfield, Adam J., Maxwell, Evan K., O’Keeffe, Sean, Orelus, Max, Panea, Razvan, Polanco, Tommy, Rasool, Ayesha, Salerno, William, Staples, Jeffrey C., Sun, Kathie, Backman, Joshua, Damask, Amy, Ferreira, Manuel Allen Revez, Ghosh, Arkopravo, Gurski, Lauren, Jorgenson, Eric, Kang, Hyun Min, Kessler, Michael, Kosmicki, Jack, Li, Alexander, Lin, Nan, Locke, Adam, Mbatchou, Joelle, Moscati, Arden, Paulding, Charles, Sidore, Carlo, Stahl, Eli, Ye, Bin, Coppola, Giovanni, Bovijn, Jonas, Siminovitch, Katherine, Praveen, Kavita, Lotta, Luca A., Kapoor, Manav, Verweij, Niek, Sosina, Olukayode, Akbari, Parsa, Nakka, Priyanka, Gokhale, Sujit, De, Tanima, Rajagopal, Veera, Shuldiner, Alan, Tzoneva, Gannie, Rodriguez-Flores, Juan, Jones, Marcus B., LeBlanc, Michelle G., Mighty, Jason, Mitnaul, Lyndon J., Nishtala, Nirupama, Rana, Nadia, Hernandez, Jaimee, Abecasis, Goncalo, Baras, Aris, Deubler, Andrew, Economides, Aris, Lotta, Luca A.

“…This study investigates the frequency of a clinically reported variant in PMS2, NM_000535.7:c.2523G>A p.(W841∗), from next-generation sequencing studies in 2…”
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Utility of Automated Protocols, Qdots and Quantitative Tissue Image Analysis for in‐situ Biomarker Studies by Pestano, Gary Anthony, Carpenter, Anne, Ashworth‐Sharpe, Julia, Vanpatten, Kristie, Haubein, Ned, LeFever, Mark, Palting, John, Riley, Janice, Kosmeder, Jerome, Lett, Scott, Bieniarz, Chris, Miller, Philip

“…Abstract only Analyses of biomarkers in tissues represent a critical component in the development of therapeutics. In oncology drug development, entire…”
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Simultaneous Detection and Quantitation of Multiple Antigen Expression in Tissue by Fluorescence Microscopy and Hyper-spectral Imaging (132.4) by Carpenter, Anne, Chatigny, Julie, LeFever, Mark, Ashworth-Sharpe, Julia, Haubein, Ned, Vanpatten, Kristie, Kosmeder, Jerry, Lett, Scott, Grogan, Thomas, Bieniarz, Chris, Miller, Philip, Pestano, Gary

“…Abstract Analyses of biomarkers in tissues represent a critical component in the development of therapeutics. In drug development, entire signaling pathways…”
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Koch carbonylation of methyl tert-butyl ether: Challenges in liquid phase mechanistic modeling and many -body optimization by Haubein, Ned Charles

“…Methyl tert-butyl ether (MTBE) is a widely used additive in oxygenated gasoline that has recently come under environmental pressure. Consequently, the demand…”
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13C NMR study of the acid-catalyzed carbonylation of methyl tert-butyl ether (MTBE) by HAUBEIN, Ned C, BROADBELT, Linda J, MOZCLESKI, Edmund J, SCHLOSBERG, Richard H, COOK, Raymond A, MEHNERT, Christian P, FARCASIU, Dan

“…Methyl tert-butyl ether (MTBE) is a widely used additive in oxygenated gasoline that has recently been identified as a potential health threat to the drinking…”
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