Search Results - "Hatzopoulos, N."
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Centriole assembly at a glance
Published in Journal of cell science (20-02-2019)“…The centriole organelle consists of microtubules (MTs) that exhibit a striking 9-fold radial symmetry. Centrioles play fundamental roles across eukaryotes,…”
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The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding
Published in Structure (London) (02-08-2016)“…Centrioles are microtubule-based structures that play important roles notably in cell division and cilium biogenesis. CEP135/Bld10p family members are…”
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Structural Analysis of the G-Box Domain of the Microcephaly Protein CPAP Suggests a Role in Centriole Architecture
Published in Structure (London) (05-11-2013)“…Centrioles are evolutionarily conserved eukaryotic organelles composed of a protein scaffold surrounded by sets of microtubules organized with a 9-fold radial…”
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Kinetic and structural roles for the surface in guiding SAS-6 self-assembly to direct centriole architecture
Published in Nature communications (26-10-2021)“…Discovering mechanisms governing organelle assembly is a fundamental pursuit in biology. The centriole is an evolutionarily conserved organelle with a…”
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Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly
Published in Nature communications (21-06-2021)“…Centrioles are evolutionarily conserved multi-protein organelles essential for forming cilia and centrosomes. Centriole biogenesis begins with self-assembly of…”
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Chemical Probe for Imaging of Polo-like Kinase 4 and Centrioles
Published in JACS Au (28-08-2023)“…Polo-like kinase (Plk4) is a serine/threonine-protein kinase that is essential for biogenesis of the centriole organelle and is enriched at centrioles. Herein,…”
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Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry
Published in Proceedings of the National Academy of Sciences - PNAS (09-07-2013)“…Centrioles are evolutionary conserved organelles that give rise to cilia and flagella as well as centrosomes. Centrioles display a characteristic ninefold…”
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The centriolar protein CPAP G-box: an amyloid fibril in a single domain
Published in Biochemical Society transactions (01-10-2015)“…Centrioles are evolutionarily conserved cylindrical cell organelles with characteristic radial symmetry. Despite their considerable size (400 nm × 200 nm, in…”
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The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation
Published in eLife (29-05-2015)“…Centrioles are microtubule-based organelles crucial for cell division, sensing and motility. In Caenorhabditis elegans, the onset of centriole formation…”
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Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel
Published in Structure (London) (05-05-2022)“…Centrioles are eukaryotic organelles that template the formation of cilia and flagella, as well as organize the microtubule network and the mitotic spindle in…”
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Structural Basis for the Carbohydrate Recognition of the Sclerotium rolfsii Lectin
Published in Journal of molecular biology (11-05-2007)“…The crystal structure of a novel fungal lectin from Sclerotium rolfsii (SRL) in its free form and in complex with N-acetyl- d-galactosamine (GalNAc) and…”
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Novel features of centriole polarity and cartwheel stacking revealed by cryo‐tomography
Published in The EMBO journal (16-11-2020)“…Centrioles are polarized microtubule‐based organelles that seed the formation of cilia, and which assemble from a cartwheel containing stacked ring oligomers…”
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The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release
Published in Brain (London, England : 1878) (21-11-2022)“…Humans carrying the CORD7 (cone-rod dystrophy 7) mutation possess increased verbal IQ and working memory. This autosomal dominant syndrome is caused by the…”
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Satellite observation of CH4 and CO anomalies associated with the Wenchuan MS 8.0 and Lushan MS 7.0 earthquakes in China
Published in Chemical geology (10-10-2017)“…Spatial and temporal variations of total column of CH4 and CO (TotCH4 and TotCO) associated with the 12 May 2008 Wenchuan and 20 April 2013 Lushan earthquakes…”
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Structure of translation initiation factor 1 from Mycobacterium tuberculosis and inferred binding to the 30S ribosomal subunit
Published in FEBS letters (05-03-2010)“…The crystal structure of the free form of IF1 from Mycobacterium tuberculosis has been determined at 1.47 Å resolution. The structure adopts the expected OB…”
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The binding of IMP to Ribonuclease A
Published in The FEBS journal (01-08-2005)“…The binding of inosine 5′ phosphate (IMP) to ribonuclease A has been studied by kinetic and X‐ray crystallographic experiments at high (1.5 Å) resolution. IMP…”
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Proximity gettering of transition metals in separation by implanted oxygen structures
Published in Applied physics letters (13-11-1995)“…The gettering behavior of Cu and Fe in ion beam synthesized silicon on insulator (SOI) material incorporating a buried oxide layer is investigated before and…”
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Satellite observation of CH 4 and CO anomalies associated with the Wenchuan M S 8.0 and Lushan M S 7.0 earthquakes in China
Published in Chemical geology (01-10-2017)Get full text
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19
Low-temperature anodic oxidation of silicon using a wave resonance plasma source
Published in Applied physics letters (02-08-1999)Get full text
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Ellipsometric investigation of damage distribution in low energy boron implantation of silicon
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01-05-1997)“…As the scaling of silicon devices to 100 nm channel length requires the formation of ultra-shallow (< 60 nm) junctions, high depth resolution analytical…”
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