In vitro lymphocytic stimulation with PPD

In vitro lymphocytic stimulation with PPD

One-way mixed lymphocyte reaction with PPD in healthy volunteers and in patients suffering from tuberculosis gave us no correlation with the degree of Mantoux sensitization. There were two major indications for further study: (a) An adequate stimulation index (SI) against PPD in vitro in tuberculosi...

Full description

Saved in:
Bibliographic Details
Published in:Respiration Vol. 48; no. 2; p. 168
Main Authors: Spyropoulos, K B, Hatzigiannaki, K
Format: Journal Article
Language:English
Published: Switzerland 1985
Subjects:
Humans
Lymphocyte Activation
Reference Values
Tuberculin
Tuberculin Test
Tuberculosis - immunology
Online Access:Get more information
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:One-way mixed lymphocyte reaction with PPD in healthy volunteers and in patients suffering from tuberculosis gave us no correlation with the degree of Mantoux sensitization. There were two major indications for further study: (a) An adequate stimulation index (SI) against PPD in vitro in tuberculosis patients correlated with satisfactory treatment results in a higher percentage than did a low stimulation index. (b) In patients, a lower PPD concentration seems to be needed for a stimulation index greater than one than in healthy individuals.
ISSN:0025-7931
DOI:10.1159/000194819