Search Results - "Hattori, Tomoyasu"

G2A Plays Proinflammatory Roles in Human Keratinocytes under Oxidative Stress as a Receptor for 9-Hydroxyoctadecadienoic Acid by Hattori, Tomoyasu, Obinata, Hideru, Ogawa, Ai, Kishi, Mikiko, Tatei, Kazuaki, Ishikawa, Osamu, Izumi, Takashi

“…G2A is a stress-inducible G protein-coupled receptor for oxidized free fatty acids, such as 9-hydroxyoctadecadienoic acid (HODE). As skin is routinely and…”
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Identification of 9-Hydroxyoctadecadienoic Acid and Other Oxidized Free Fatty Acids as Ligands of the G Protein-coupled Receptor G2A by Obinata, Hideru, Hattori, Tomoyasu, Nakane, Shinji, Tatei, Kazuaki, Izumi, Takashi

“…G2A is a G protein-coupled receptor that is predominantly expressed in lymphoid tissues and macrophages. G2A can be induced by diverse stimuli to cause cell…”
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Isolated cutaneous manifestation of IgG4-related disease by Hattori, Tomoyasu, Miyanaga, Tomomi, Tago, Osamu, Udagawa, Mai, Kamiyama, Yuka, Nagai, Yayoi, Ishikawa, Osamu

“…The cutaneous manifestation of IgG(4)-related disease has rarely been reported. The aim of this study is to identify and describe the cutaneous manifestations…”
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Four Japanese cases of dendritic cell neurofibroma with pseudorosettes by Hattori, Tomoyasu, Fukumoto, Takaya, Anan, Takashi, Kimura, Tetsunori

“…Dendritic cell neurofibroma with pseudorosettes (DCNWPR) is a rare peripheral nerve sheath tumor (PNST). To our knowledge, the only reported case of DCNWPR in…”
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Analysis of clinical symptoms and ABCC6 mutations in 76 Japanese patients with pseudoxanthoma elasticum by Iwanaga, Akira, Okubo, Yumi, Yozaki, Mariko, Koike, Yuta, Kuwatsuka, Yutaka, Tomimura, Saori, Yamamoto, Yosuke, Tamura, Hiroshi, Ikeda, Satoshi, Maemura, Koji, Tsuiki, Eiko, Kitaoka, Takashi, Endo, Yuichiro, Mishima, Hiroyuki, Yoshiura, Koh‐Ichiro, Ogi, Tomoo, Tanizaki, Hideaki, Wataya‐Kaneda, Mari, Hattori, Tomoyasu, Utani, Atsushi

“…Pseudoxanthoma elasticum (PXE) is a hereditary disease, causing calcification and degeneration of elastic fibers, which affects the skin, eye, cardiovascular…”
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No association of atherosclerosis with digital ulcers in Japanese patients with systemic sclerosis: Evaluation of carotid intima-media thickness and plaque characteristics by Motegi, Sei-ichiro, Toki, Sayaka, Hattori, Tomoyasu, Yamada, Kazuya, Uchiyama, Akihiko, Ishikawa, Osamu

“…Patients with systemic sclerosis (SSc) usually develop Raynaud's phenomenon, persistent digital ischemia and sometimes develop digital ulcers (DU). Several…”
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The prevalence of Merkel cell polyomavirus in Japanese patients with Merkel cell carcinoma by Hattori, Tomoyasu, Takeuchi, Yuko, Takenouchi, Tatsuya, Hirofuji, Akiko, Tsuchida, Tetsuya, Kabumoto, Takenori, Fujiwara, Hiroshi, Ito, Masaaki, Shimizu, Akira, Okada, Etsuko, Motegi, Sei-ichiro, Tamura, Atsushi, Ishikawa, Osamu

“…Abstract Background A novel polyomavirus, the Merkel cell polyomavirus (MCPyV) has been implicated in the pathogenesis of Merkel cell carcinoma (MCC); however,…”
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First Japanese case of atypical progeroid syndrome/atypical Werner syndrome with heterozygous LMNA mutation by Motegi, Sei-ichiro, Yokoyama, Yoko, Uchiyama, Akihiko, Ogino, Sachiko, Takeuchi, Yuko, Yamada, Kazuya, Hattori, Tomoyasu, Hashizume, Hiroaki, Ishikawa, Yuichi, Goto, Makoto, Ishikawa, Osamu

“…Atypical progeroid syndrome (APS), including atypical Werner syndrome (AWS), is a progeroid syndrome involving heterozygous mutations in the LMNA gene encoding…”
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Clinical follow-up study of adult-onset Still's disease by NAGAI, Yayoi, HASEGAWA, Michiko, OKADA, Etsuko, HATTORI, Tomoyasu, TAGO, Osamu, ISHIKAWA, Osamu

“…Eighteen patients with adult‐onset Still’s disease have been followed up for 3–22 years in our department. Initial manifestations were fever with skin rash in…”
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Identification and analysis of two splice variants of human G2A generated by alternative splicing by Ogawa, Ai, Obinata, Hideru, Hattori, Tomoyasu, Kishi, Mikiko, Tatei, Kazuaki, Ishikawa, Osamu, Izumi, Takashi

“…G2A is a G protein-coupled receptor that can be induced by various stressors. G2A is reported to have proton-sensing activity that mediates intracellular…”
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Bosentan for digital ulcers in patients with systemic sclerosis by NAGAI, Yayoi, HASEGAWA, Michiko, HATTORI, Tomoyasu, OKADA, Etsuko, TAGO, Osamu, ISHIKAWA, Osamu

“…Recurrent digital ulcers are manifestations of vascular disease in patients with systemic sclerosis (SSc). We report six patients with severe digital ulcers…”
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Clinical analysis of leg ulcers and gangrene in rheumatoid arthritis by Hasegawa, Michiko, Nagai, Yayoi, Sogabe, Yoko, Hattori, Tomoyasu, Inoue, Chizuru, Okada, Etsuko, Tago, Osamu, Ishikawa, Osamu

“…Leg ulcers are often complicated in patients with rheumatoid arthritis (RA), however, the etiology is multifactorial. We examined the cases of leg ulceration…”
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Alopecia in a patient with Vogt-Koyanagi-Harada disease by Shimizu, Akira, Kamiyama, Yuka, Kato, Madoka, Hattori, Tomoyasu, Motegi, Sei-ichiro, Amano, Hiroo, Ishikawa, Osamu

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Leukemia cutis in a patient with acute monocytic leukemia presenting as unique facial erythema by HATTORI, Tomoyasu, AMANO, Hiroo, NAGAI, Yayoi, ISHIKAWA, Osamu

“…ABSTRACT A 67‐year‐old woman was referred to our department with a 1‐month history of facial exanthemas. She had been diagnosed as having acute monocytic…”
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Ceramide Induces Myogenic Differentiation and Apoptosis in Drosophila Schneider Cells by Kawamura, Hidemasa, Tatei, Kazuaki, Nonaka, Tetsuo, Obinata, Hideru, Hattori, Tomoyasu, Ogawa, Ai, Kazama, Hideko, Hamada, Nobuyuki, Funayama, Tomoo, Sakashita, Tetsuya, Kobayashi, Yasuhiko, Nakano, Takashi, Izumi, Takashi

“…Cells exposed to genotoxic stress, such as ionizing radiation and DNA damaging reagents, either arrest the cell cycle to repair the genome, or undergo…”
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Unilateral Generalized Morphea in Childhood by Nagai, Yayoi, Hattori, Tomoyasu, Ishikawa, Osamu

“…We report a 6‐year‐old boy with unilateral generalized morphea distributing on the right side of his lower leg, trunk, and upper arm. A skin biopsy from the…”
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A Case of Hypersensitivity Syndrome due to Phenytoin by Nagai, Yayoi, Hattori, Tomoyasu, Ishikawa, Osamu

“…We report a 30‐year‐old female with hypersensitivity syndrome (HS) due to phenytoin. Her disease course was typical with elevation of the antibody titer for…”
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Skin surface material for detecting human papillomavirus infection of skin warts by Kuriyama, Yuko, Kosaka, Mieko, Kaneko, Akira, Nishioka, Hirokazu, Anzawa, Kazushi, Hattori, Tomoyasu, Igarashi, Naoya, Tamura, Masaaki, Motegi, Sei‐ichiro, Shimizu, Akira

“…Abstract Warts, caused by human papillomavirus (HPV) infection, have various clinical presentations, making them difficult to differentiate from clavus,…”
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Global DNA hypomethylation and hypoxia-induced expression of the ten eleven translocation (TET) family, TET1, in scleroderma fibroblasts by Hattori, Mai, Yokoyama, Yoko, Hattori, Tomoyasu, Motegi, Sei-ichiro, Amano, Hiroo, Hatada, Izuho, Ishikawa, Osamu

“…The precise mechanisms of tissue fibrosis have not yet been elucidated in systemic sclerosis (SSc). However, studies of the regulation of DNA methylation, the…”
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Efficacy and safety of nemolizumab and topical corticosteroids for prurigo nodularis: Results from a randomised, double-blind, placebo-controlled, phase II/III clinical study in patients aged ≥13 years by Yokozeki, Hiroo, Murota, Hiroyuki, Matsumura, Takayo, Komazaki, Hiroshi

“…Prurigo nodularis, a chronic inflammatory skin condition, adversely affects the quality of life of affected individuals. Current treatment options for prurigo…”
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