Search Results - "Hatton, William J"

MicroRNAs dynamically remodel gastrointestinal smooth muscle cells by Park, Chanjae, Yan, Wei, Ward, Sean M, Hwang, Sung Jin, Wu, Qiuxia, Hatton, William J, Park, Jong Kun, Sanders, Kenton M, Ro, Seungil

“…Smooth muscle cells (SMCs) express a unique set of microRNAs (miRNAs) which regulate and maintain the differentiation state of SMCs. The goal of this study was…”
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Expression, localization, and functional properties of Bestrophin 3 channel isolated from mouse heart by O'Driscoll, Kate E, Hatton, William J, Burkin, Heather R, Leblanc, Normand, Britton, Fiona C

“…Bestrophins are a novel family of proteins that encode calcium-activated chloride channels. In this study we establish that Bestrophin transcripts are…”
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Functional role of CLC-2 chloride inward rectifier channels in cardiac sinoatrial nodal pacemaker cells by Huang, Z. Maggie, Prasad, Chaithra, Britton, Fiona C, Ye, Linda L, Hatton, William J, Duan, Dayue

“…Abstract A novel Cl− inward rectifier channel (Cl,ir) encoded by ClC-2 , a member of the ClC voltage-gated Cl− channel gene superfamily, has been recently…”
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ClC‐3 chloride channel is upregulated by hypertrophy and inflammation in rat and canine pulmonary artery by Dai, Yan‐Ping, Bongalon, Shaner, Hatton, William J, Hume, Joseph R, Yamboliev, Ilia A

“…1 Cl− channels have been implicated in essential cellular functions including volume regulation, progression of cell cycle, cell proliferation and contraction,…”
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Cell culture alters Ca2+ entry pathways activated by store-depletion or hypoxia in canine pulmonary arterial smooth muscle cells by Ng, Lih Chyuan, Kyle, Barry D, Lennox, Alison R, Shen, Xiao-Ming, Hatton, William J, Hume, Joseph R

“…Previous studies have shown that, in acutely dispersed canine pulmonary artery smooth muscle cells (PASMCs), depletion of both functionally independent…”
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Altered properties of volume-sensitive osmolyte and anion channels (VSOACs) and membrane protein expression in cardiac and smooth muscle myocytes from Clcn3-/- mice by Yamamoto‐Mizuma, Shintaro, Wang, Ge‐Xin, Liu, Luis L., Schegg, Kathleen, Hatton, William J., Duan, Dayue, Horowitz, Burton, Lamb, Fred S., Hume, Joseph R.

“…ClC-3, a member of the large superfamily of ClC voltage-dependent Cl – channels, has been proposed as a molecular candidate responsible for volume-sensitive…”
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Molecular markers expressed in cultured and freshly isolated interstitial cells of Cajal by Epperson, A, Hatton, W J, Callaghan, B, Doherty, P, Walker, R L, Sanders, K M, Ward, S M, Horowitz, B

“…Located within the tunica muscularis of the gastrointestinal (GI) tract are networks of cells known as interstitial cells of Cajal (ICC). ICC are critical for…”
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Functional effects of novel anti-ClC-3 antibodies on native volume-sensitive osmolyte and anion channels in cardiac and smooth muscle cells by Wang, Ge-Xin, Hatton, William J, Wang, Grace L, Zhong, Juming, Yamboliev, Ilia, Duan, Dayue, Hume, Joseph R

“…Whether ClC-3 encodes volume-sensitive organic osmolyte and anion channels (VSOACs) remains controversial. We have shown previously that native VSOACs in some…”
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Functional inhibition of native volume-sensitive outwardly rectifying anion channels in muscle cells and Xenopus oocytes by anti-ClC-3 antibody by Duan, Dayue, Zhong, Juming, Hermoso, Marcela, Satterwhite, Christina M., Rossow, Charles F., Hatton, William J., Ilia Yamboliev, Horowitz, Burton, Hume, Joseph R.

“…Intracellular dialysis of NIH/3T3 cells with a commercially available anti-ClC-3 polyclonal antibody (Ab) for ≈30 min completely inhibited expressed…”
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Characterization of the A-type potassium current in murine gastric antrum by Amberg, Gregory C., Baker, Salah A., Koh, Sang Don, Hatton, William J., Murray, Keith J., Horowitz, Burton, Sanders, Kenton M.

“…A-type currents are rapidly inactivating potassium currents that operate at subthreshold potentials. A-type currents have not been reported to occur in the…”
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CARDIAC-SPECIFIC OVEREXPRESSION OF THE HUMAN SHORT CLC-3 CHLORIDE CHANNEL ISOFORM IN MICE by Xiong, Dazhi, Wang, Ge-Xin, Burkin, Dean J, Yamboliev, Ilia A, Singer, Cherie A, Rawat, Shanti, Scowen, Paul, Evans, Rebecca, Ye, Linda, Hatton, William J, Tian, Honglin, Keller, Phillip S, McCloskey, Diana T, Duan, Dayue, Hume, Joseph R

“…SUMMARY 1 ClC‐3 has been proposed as a molecular candidate responsible for volume‐sensitive outwardly rectifying anion channels (VSOAC) in cardiac and smooth…”
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Functional and molecular expression of a voltage-dependent K+ channel (Kv1.1) in interstitial cells of Cajal by Hatton, William J., Mason, Helen S., Carl, Andreas, Doherty, Philip, Latten, Mark J., Kenyon, James L., Sanders, Kenton M., Horowitz, Burton

“…Located within the gastrointestinal (GI) musculature are networks of cells known as interstitial cells of Cajal (ICC). ICC are associated with several…”
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Contribution of Kv4 channels toward the A-type potassium current in murine colonic myocytes by Amberg, Gregory C., Koh, Sang Don, Hatton, William J., Murray, Keith J., Monaghan, Kevin, Horowitz, Burton, Sanders, Kenton M.

“…A rapidly inactivating K + current (A-type current; I A ) present in murine colonic myocytes is important in maintaining physiological patterns of slow wave…”
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Targeted inactivation of cystic fibrosis transmembrane conductance regulator chloride channel gene prevents ischemic preconditioning in isolated mouse heart by Chen, Hong, Liu, Luis L, Ye, Linda L, McGuckin, Conor, Tamowski, Susan, Scowen, Paul, Tian, Honglin, Murray, Keith, Hatton, William J, Duan, Dayue

“…Recent evidence suggests that chloride channels may be involved in ischemic preconditioning (IPC). In this study, we tested whether the cystic fibrosis…”
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Platelet‐derived growth factor receptor‐α cells in mouse urinary bladder: a new class of interstitial cells by Koh, Byoung H., Roy, Rishiparna, Hollywood, Mark A., Thornbury, Keith D., McHale, Noel G., Sergeant, Gerard P., Hatton, William J., Ward, Sean M., Sanders, Kenton M., Koh, Sang Don

“…Specific classes of interstitial cells exist in visceral organs and have been implicated in several physiological functions including pacemaking and mediators…”
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Molecular distribution of volume-regulated chloride channels (ClC-2 and ClC-3) in cardiac tissues by Britton, F C, Hatton, W J, Rossow, C F, Duan, D, Hume, J R, Horowitz, B

“…The molecular identification of cardiac chloride channels has provided probes to investigate their distribution and abundance in heart. In this study, the…”
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Serum Response Factor–Dependent MicroRNAs Regulate Gastrointestinal Smooth Muscle Cell Phenotypes by Park, Chanjae, Hennig, Grant W, Sanders, Kenton M, Cho, Jonathan H, Hatton, William J, Redelman, Doug, Park, Jong Kun, Ward, Sean M, Miano, Joseph M, Yan, Wei, Ro, Seungil

“…Background & Aims Smooth muscle cells (SMCs) change phenotypes under various pathophysiological conditions. These changes are largely controlled by the serum…”
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Regulation of volume-sensitive outwardly rectifying anion channels in pulmonary arterial smooth muscle cells by PKC by Zhong, Juming, Wang, Ge-Xin, Hatton, William J, Yamboliev, Ilia A, Walsh, Michael P, Hume, Joseph R

“…We tested the possible role of endogenous protein kinase C (PKC) in the regulation of native volume-sensitive organic osmolyte and anion channels (VSOACs) in…”
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Novel regulation of the A-type K+ current in murine proximal colon by calcium-calmodulin-dependent protein kinase II by Koh, Sang Don, Perrino, Brian A., Hatton, William J., Kenyon, James L., Sanders, Kenton M.

“…The kinetics of inactivation of delayed rectifier K + current in murine colonic myocytes differed in amphotericin-permeabilized patch and conventional patch…”
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Role of TREK-1 potassium channel in bladder overactivity after partial bladder outlet obstruction in mouse by Baker, Salah A, Hatton, William J, Han, Junguk, Hennig, Grant W, Britton, Fiona C, Koh, Sang Don

“…Mouse models of partial bladder outlet obstruction cause bladder hypertrophy. Expression of a number of ion channels is altered in hypertrophic detrusor…”
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