Search Results - "Hatthakarnkul, Phimmada"

High expression of STAT3 within the tumour‐associated stroma predicts poor outcome in breast cancer patients by Morrow, Elizabeth, Pennel, Kathryn, Hatthakarnkul, Phimmada, Leslie, Holly, Mallon, Elizabeth, Andersen, Ditte, Jamieson, Nigel, McMillan, Donald, Roseweir, Antonia, Edwards, Joanne

“…Introduction Triple‐negative breast cancer (TNBC) patients have the poorest clinical outcomes compared to other molecular subtypes of breast cancer…”
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TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer by Galbraith, Norman J., Quinn, Jean A., Al-Badran, Sara Sf, Pennel, Kathryn A.F., Hillson, Lily V.S., Hatthakarnkul, Phimmada, McKenzie, Molly, Maka, Noori, Loi, Lynette, Frixou, Mikaela, Steele, Colin W., Roxburgh, Campbell S., Horgan, Paul G., McMillan, Donald C., Edwards, Joanne

“…•There is an unmet need for novel target discovery in microsatellite-stable colorectal cancer.•A cohort of 875 patients with resected colorectal cancer…”
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Histopathological tumour microenvironment score independently predicts outcome in primary operable colorectal cancer by Hatthakarnkul, Phimmada, Pennel, Kathryn, Alexander, Peter, Wyk, Hester, Roseweir, Antonia, Inthagard, Jitwadee, Hay, Jennifer, Andersen, Ditte, Maka, Noori, Park, James, Roxburgh, Campbell, Thuwajit, Chanitra, McMillan, Donald, Edwards, Joanne

“…Colorectal cancer (CRC) is a heterogenous malignancy and research is focused on identifying novel ways to subtype patients. In this study, a novel…”
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Cellular localization of nucleolin determines the prognosis in cancers: a meta-analysis by Yangngam, Supaporn, Prasopsiri, Jaturawitt, Hatthakarnkul, Phimmada, Thongchot, Suyanee, Thuwajit, Peti, Yenchitsomanus, Pa-thai, Edwards, Joanne, Thuwajit, Chanitra

“…Nucleolin (NCL) is a multifunctional protein expressed in the nucleus, cytoplasm, and cell membrane. Overexpression of NCL has a controversial role as a poor…”
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Effect of spatial transcriptomic-derived intrinsic epithelial signatures on immune cell recruitment and behaviour in the microenvironment of colorectal cancer by Wood, Colin, Hatthakarnkul, Phimmada, Leslie, Holly, Legrini, Assya, Cameron, Andrew, Pennel, Kathryn AF, Sansom, Owen J, Edwards, Joanne, Jamieson, Nigel Balfour, Steele, Colin William

“…251 Background: Colorectal Cancer (CRC) remains a significant healthcare problem. Interest in the role of the Tumour Microenvironment (TME) in progression and…”
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Association of punctate TAK1 expression with mortality in patients with microsatellite-stable colorectal cancer by Galbraith, Norman James, Al-Badran, Sara SF, Hatthakarnkul, Phimmada, Pennel, Kathryn AF, Quinn, Jean A., Loi, Lynette, Maka, Noori, Steele, Colin William, Roxburgh, Campbell SD, McMillan, Donald C., Horgan, Paul G., Edwards, Joanne

“…220 Background: Microsatellite stable (MSS) colorectal cancer continues to have limited options for personalised therapeutic targets. The NFKB pathway is known…”
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Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer by Hatthakarnkul, Phimmada, Quinn, Jean A, Ammar, Aula, Lynch, Gerard, Van Wyk, Hester, McMillan, Donald C, Thuwajit, Chanitra, Edwards, Joanne

“…Colorectal cancer (CRC) is the third most common cancer worldwide. Poor survival of CRC associated with the development of tumour metastasis led to the…”
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Systematic review of tumour budding and association with common mutations in patients with colorectal cancer by Hatthakarnkul, Phimmada, Quinn, Jean A., Matly, Amna Ahmed Mohemmd, Ammar, Aula, van Wyk, Hester C., McMillan, Donald C., Edwards, Joanne

“…[Display omitted] •Meta-analysis evaluated relationship between mutated KRAS/BRAF or MSI tumour and tumour budding in colorectal cancer patients.•17 potential…”
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Spatial transcriptomic analysis of tumour with high and low CAIX expression in TNBC tissue samples using GeoMx™ RNA assay by Shamis, Suad Ak, Savioli, Francesca, Ammar, Aula, Al-Badran, Sara Sf, Hatthakarnkul, Phimmada, Leslie, Holly, Mallon, Elizabeth Ea, Jamieson, Nigel B, McMillan, Donald C, Edwards, Joanne

“…Prognostic significance and gene signatures associated with carbonic anhydrase IX (CAIX) was investigated in triple negative breast cancer (TNBC) patients…”
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Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer by Hatthakarnkul, Phimmada, Ammar, Aula, Pennel, Kathryn A F, Officer-Jones, Leah, Cusumano, Silvia, Quinn, Jean A, Matly, Amna Ahmed Mohemmed, Alexander, Peter G, Hay, Jennifer, Andersen, Ditte, Lynch, Gerard, van Wyk, Hester C, Maka, Noori, McMillan, Donald C, Le Quesne, John, Thuwajit, Chanitra, Edwards, Joanne

“…Colorectal cancer (CRC) is the third most diagnosed cancer worldwide. Despite a well-established knowledge of tumour development, biomarkers to predict patient…”
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JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors by Pennel, Kathryn A F, Hatthakarnkul, Phimmada, Wood, Colin S, Lian, Guang-Yu, Al-Badran, Sara S F, Quinn, Jean A, Legrini, Assya, Inthagard, Jitwadee, Alexander, Peter G, van Wyk, Hester, Kurniawan, Ahmad, Hashmi, Umar, Gillespie, Michael A, Mills, Megan, Ammar, Aula, Hay, Jennifer, Andersen, Ditte, Nixon, Colin, Rebus, Selma, Chang, David K, Kelly, Caroline, Harkin, Andrea, Graham, Janet, Church, David, Tomlinson, Ian, Saunders, Mark, Iveson, Tim, Lannagan, Tamsin R M, Jackstadt, Rene, Maka, Noori, Horgan, Paul G, Roxburgh, Campbell S D, Sansom, Owen J, McMillan, Donald C, Steele, Colin W, Jamieson, Nigel B, Park, James H, Roseweir, Antonia K, Edwards, Joanne

“…Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of cellular signaling pathways. Previous literature has implicated aberrant…”
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Abstract 3231: Temporal changes in intratumoral and systemic lymphocytes in response to short and long course radiotherapy regimens in locally advanced rectal cancer by Hillson, Lily V., McMahon, Ross K., Pennel, Kathryn A., Quinn, Jean A., Jones, Leia, Amirkhah, Raheleh, Ammar, Aula, Hatthakarnkul, Phimmada, Ferguson, Annabelle, Milling, Simon W., McDonald, Alec, Dunne, Philip D., Edwards, Joanne, O'Cathail, Sean M., Roxburgh, Campbell S.

“…Abstract Background. Two pre-operative radiotherapy (RT) regimens are in common use for patients (pts) with locally advanced rectal cancer (LARC):…”
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Abstract 5558: Understanding the molecular mechanism of tumor budding and its relationship with tumor microenvironment in colorectal cancer by Hatthakarnkul, Phimmada, Leslie, Holly, Van Wyk, Hester, Officer-Jones, Leah, Cusumano, Silvia, Ammar, Aula, Pennel, Kathryn A.F., Quinn, Jean A., Hay, Jennifer, Park, James, Maka, Noori, Quesne, John Le, Thuwajit, Chanitra, Jamieson, Nigel, Edwards, Joanne

“…Abstract Background: Tumor budding (TB), a single or cluster of up to 4 cells at the tumor-invasive front, is a well-established prognostic marker and an…”
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Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target by Vande Voorde, Johan, Steven, Rory T., Najumudeen, Arafath K., Ford, Catriona A., Dexter, Alex, Gonzalez-Fernandez, Ariadna, Nikula, Chelsea J., Xiang, Yuchen, Ford, Lauren, Maneta Stavrakaki, Stefania, Gilroy, Kathryn, Zeiger, Lucas B., Pennel, Kathryn, Hatthakarnkul, Phimmada, Elia, Efstathios A., Nasif, Ammar, Murta, Teresa, Manoli, Eftychios, Mason, Sam, Gillespie, Michael, Lannagan, Tamsin R. M., Vlahov, Nikola, Ridgway, Rachel A., Nixon, Colin, Raven, Alexander, Mills, Megan, Athineos, Dimitris, Kanellos, Georgios, Nourse, Craig, Gay, David M., Hughes, Mark, Burton, Amy, Yan, Bin, Sellers, Katherine, Wu, Vincen, De Ridder, Kobe, Shokry, Engy, Huerta Uribe, Alejandro, Clark, William, Clark, Graeme, Kirschner, Kristina, Thienpont, Bernard, Li, Vivian S. W., Maddocks, Oliver D. K., Barry, Simon T., Goodwin, Richard J. A., Kinross, James, Edwards, Joanne, Yuneva, Mariia O., Sumpton, David, Takats, Zoltan, Campbell, Andrew D., Bunch, Josephine, Sansom, Owen J.

“…The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC , and oncogenic mutations such as mutant…”
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