Search Results - "Hatano, Masaki"

Sealutomicins, new enediyne antibiotics from the deep-sea actinomycete Nonomuraea sp. MM565M-173N2 by Igarashi, Masayuki, Sawa, Ryuichi, Umekita, Maya, Hatano, Masaki, Arisaka, Rie, Hayashi, Chigusa, Ishizaki, Yoshimasa, Suzuki, Masato, Kato, Chiaki

“…A Nonomuraea sp. strain MM565M-173N2 was isolated from deep-sea sediment off the Sanriku coast, and new antibiotics were evaluated against carbapenem-resistant…”
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Fradiamine A, a new siderophore from the deep-sea actinomycete Streptomyces fradiae MM456M-mF7 by Takehana, Yasuhiro, Umekita, Maya, Hatano, Masaki, Kato, Chiaki, Sawa, Ryuichi, Igarashi, Masayuki

“…New bioactive substances were identified from several marine actinomycetes strains by LC-HRESI-MS based non-targeted metabolomics. A new siderophore and its…”
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Dialysis-related carpal tunnel syndrome in the past 40 years by Hatano, Masaki, Kitajima, Izuru, Yamamoto, Seizo, Nakamura, Masaki, Isawa, Kazuya, Suwabe, Tatsuya, Hoshino, Junichi, Sawa, Naoki, Ubara, Yoshifumi

“…Purpose and method Patients on hemodialysis develop carpal tunnel syndrome (CTS) due to an accumulation of dialysis-related β2 microglobulin (β2m) amyloid…”
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An efficient CRISPR interference-based prediction method for synergistic/additive effects of novel combinations of anti-tuberculosis drugs by Samukawa, Noriaki, Yamaguchi, Takehiro, Ozeki, Yuriko, Matsumoto, Sohkichi, Igarashi, Masayuki, Kinoshita, Naoko, Hatano, Masaki, Tokudome, Kentaro, Matsunaga, Shinji, Tomita, Shuhei

“…Tuberculosis (TB) is treated by chemotherapy with multiple anti-TB drugs for a long period, spanning 6 months even in a standard course. In perspective, to…”
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Discovery, characterization and functional improvement of kumamonamide as a novel plant growth inhibitor that disturbs plant microtubules by Ishida, Takashi, Yoshimura, Haruna, Takekawa, Masatsugu, Higaki, Takumi, Ideue, Takashi, Hatano, Masaki, Igarashi, Masayuki, Tani, Tokio, Sawa, Shinichiro, Ishikawa, Hayato

“…The discovery and useful application of natural products can help improve human life. Chemicals that inhibit plant growth are broadly utilized as herbicides to…”
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Wychimicins, a new class of spirotetronate polyketides from Actinocrispum wychmicini MI503-A4 by Kimura, Tomoyuki, Umekita, Maya, Hatano, Masaki, Hayashi, Chigusa, Sawa, Ryuichi, Igarashi, Masayuki

“…In the course of our screening program for new anti-methicillin-resistant Staphylococcus aureus antibiotics, four novel antibiotics, termed wychimicins A–D,…”
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Letter regarding "The effects of bone-substitute augmentation on treatment of osteoporotic intertrochanteric fractures" by Hatano, Masaki, Yamamoto, Norio, Tomita, Yosuke, Koizumi, Yasuhiko, Kota, Miyoshi

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Characteristics of aspiration pneumonia patients in acute care hospitals: A multicenter, retrospective survey in Northern Japan by Suzuki, Jun, Ikeda, Ryoukichi, Kato, Kengo, Kakuta, Risako, Kobayashi, Yuta, Ohkoshi, Akira, Ishii, Ryo, Hirano-Kawamoto, Ai, Ohta, Jun, Kawata, Rei, Kanbayashi, Tomonori, Hatano, Masaki, Shishido, Tadahisa, Miyakura, Yuya, Ishigaki, Kento, Yamauchi, Yasunari, Nakazumi, Miho, Endo, Takuya, Tozuka, Hiroki, Kitaya, Shiori, Numano, Yuki, Koizumi, Shotaro, Saito, Yutaro, Unuma, Mutsuki, Hashimoto, Ken, Ishida, Eiichi, Kikuchi, Toshiaki, Kudo, Takayuki, Watanabe, Kenichi, Ogura, Masaki, Tateda, Masaru, Sasaki, Takatsuna, Ohta, Nobuo, Okazaki, Tatsuma, Katori, Yukio

“…Background Pneumonia is a common cause of illness and death of the elderly in Japan. Its prevalence is escalating globally with the aging of population. To…”
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Structures and biological activities of novel 4’-acetylated analogs of chrysomycins A and B by Wada, Shun-ichi, Sawa, Ryuichi, Iwanami, Fumiki, Nagayoshi, Miho, Kubota, Yumiko, Iijima, Kiyoko, Hayashi, Chigusa, Shibuya, Yuko, Hatano, Masaki, Igarashi, Masayuki, Kawada, Manabu

“…Two new 4’-acetylated analogs of chrysomycin were discovered during the screening for antitumor agents from the metabolites of actinomycetes. Their structures…”
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Chlorocatechelins A and B from Streptomyces sp.: New Siderophores Containing Chlorinated Catecholate Groups and an Acylguanidine Structure by Kishimoto, Shinji, Nishimura, Shinichi, Hattori, Akira, Tsujimoto, Masafumi, Hatano, Masaki, Igarashi, Masayuki, Kakeya, Hideaki

“…Two novel siderophores, chlorocatechelins A and B, were isolated from a culture broth of Streptomyces sp. Their structures were determined by spectroscopic…”
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The potent protein phosphatase 2A inhibitors aminocytostatins: new derivatives of cytostatin by Tohyama, Shigehiro, Kawada, Manabu, Muramatsu, Hideyuki, Hatano, Masaki, Inoue, Hiroyuki, Matoba, Kazuaki, Sawa, Ryuichi, Igarashi, Masayuki

“…Specific inhibitors of protein phosphatase 2A (PP2A) mediate anticancer effects by augmenting the tumor-killing activity of natural killer (NK) cells. In this…”
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ATP Depletion Assay Led to the Isolation of New 36-Membered Polyol Macrolides Deplelides A and B from Streptomyces sp. MM581-NF15 by Takeuchi, Toshifumi, Hatano, Masaki, Umekita, Maya, Hayashi, Chigusa, Wada, Shun-ichi, Nagayoshi, Miho, Sawa, Ryuichi, Kubota, Yumiko, Kawada, Manabu, Igarashi, Masayuki, Shibasaki, Masakatsu

“…New 36-membered polyol macrolides deplelides A and B were isolated from the culture of Streptomyces MM581-NF15 by bioassay-guided fractionation using an ATP…”
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Flupyranochromene, a novel inhibitor of influenza virus cap-dependent endonuclease, from Penicillium sp. f28743 by Yamasaki, Manabu, Igarashi, Masayuki, Sawa, Ryuichi, Nosaka, Chisato, Umekita, Maya, Hatano, Masaki, Kimura, Tomoyuki, Iijima, Kiyoko, Takizawa, Naoki, Kato, Taira, Mizumoto, Kiyohisa, Nomoto, Akio

“…Influenza virus RNA polymerase has cap-dependent endonuclease activity that produces capped RNA fragments for priming viral mRNA synthesis. This enzymatic…”
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Histologically Proven Recurrent Synovitis after Nivolumab Treatment by Nakayama, Yuki, Sawa, Naoki, Suwabe, Tatsuya, Yamanouchi, Masayuki, Ikuma, Daisuke, Mizuno, Hiroki, Hasegawa, Eiko, Sekine, Akinari, Oba, Yuki, Ishiwata, Kazuya, Wake, Atsushi, Hatano, Masaki, Kitajima, Izuru, Kono, Kei, Kinowaki, Keiichi, Takazawa, Yutaka, Takemura, Tamiko, Ubara, Yoshifumi

“…A 58-year-old woman with rheumatoid arthritis was diagnosed with methotrexate-associated Hodgkin lymphoma. After receiving several chemotherapy regimens, she…”
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New chloptosins B and C from an Embleya strain exhibit synergistic activity against methicillin-resistant Staphylococcus aureus when combined with co-producing compound L-156,602 by Hashizume, Hideki, Harada, Shigeko, Sawa, Ryuichi, Iijima, Kiyoko, Kubota, Yumiko, Shibuya, Yuko, Nagasaka, Ryoko, Hatano, Masaki, Igarashi, Masayuki

“…Two new dimeric cyclohexapeptides, chloptosins B and C, were discovered from the culture broth of Embleya sp. MM621-AF10 together with the known compounds…”
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Role of Src Family Kinases in Regulation of Intestinal Epithelial Homeostasis by Imada, Shinya, Murata, Yoji, Kotani, Takenori, Hatano, Masaki, Sun, Chunxiao, Konno, Tasuku, Park, Jung-ha, Kitamura, Yasuaki, Saito, Yasuyuki, Ohdan, Hideki, Matozaki, Takashi

“…Proper regulation of epithelial cell turnover is important for the structural integrity and homeostasis of various tissues, including the intestine. Here we…”
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Total Synthesis and Antimicrobial Activity of Chlorocatechelin A by Kishimoto, Shinji, Nishimura, Shinichi, Hatano, Masaki, Igarashi, Masayuki, Kakeya, Hideaki

“…Chlorocatechelin A (1) is a structurally unique microbial siderophore containing two units of 4-chloro-2,3-dihydroxybenzoic acid (CDB) and a characteristic…”
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Kribellosides, novel RNA 5′-triphosphatase inhibitors from the rare actinomycete Kribbella sp. MI481-42F6 by Igarashi, Masayuki, Sawa, Ryuichi, Yamasaki, Manabu, Hayashi, Chigusa, Umekita, Maya, Hatano, Masaki, Fujiwara, Toshinobu, Mizumoto, Kiyohisa, Nomoto, Akio

“…Yeast capping enzymes differ greatly from those of mammalian, both structurally and mechanistically. Yeast-type capping enzyme repressors are therefore…”
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A guanine derivative as a new MEK inhibitor produced by Streptomyces sp. MK63-43F2 by Iijima, Masatomi, Kubota, Yuji, Sawa, Ryuichi, Kubota, Yumiko, Hatano, Masaki, Igarashi, Masayuki, Kawada, Manabu, Momose, Isao, Takekawa, Mutsuhiro, Shibasaki, Masakatsu

“…Mitogen-activated protein kinase (MAPK) pathways that direct cellular responses are involved in various biological processes; the RAS-RAF-MEK-ERK pathway is…”
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Quadoctomycin, a 48-membered macrolide antibiotic from Streptomyces sp. MM168-141F8 by Sawa, Ryuichi, Kubota, Yumiko, Umekita, Maya, Hatano, Masaki, Hayashi, Chigusa, Igarashi, Masayuki

“…Drug-resistant bacteria are still emerging, and screening of new skeletal antibiotics is important. During our continuous screening for antimicrobial agents,…”
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