Search Results - "Hatanaka, Emily"
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Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents
Published in Science translational medicine (21-04-2021)“…Subcortical white matter stroke (WMS) accounts for up to 30% of all stroke events. WMS damages primarily astrocytes, axons, oligodendrocytes, and myelin. We…”
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In vitro and in vivo modeling systems of supratentorial ependymomas
Published in Frontiers in oncology (26-02-2024)“…Ependymomas are rare brain tumors that can occur in both children and adults. Subdivided by the tumors' initial location, ependymomas develop in the central…”
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Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs
Published in Stem cell research (01-08-2021)“…•White matter stroke accounts for up to 30% of all stroke events.•An astrocytic cell-based therapy is a strong therapeutic candidate after WMS.•Deferoxamine…”
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458 Immunologic niches of the central nervous system in a novel EGFR-mutant glioblastoma murine model of immunotherapeutic resistance
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundGlioblastoma (GBM) remains one of the deadliest cancers, with a five-year survival rate of less than 10%. Standard of care treatment has remained…”
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MODL-34. A SERIES OF EGFR-MUTANT MODELS OF GLIOBLASTOMA THAT RECAPITULATES PATIENT TUMOR HETEROGENEITY AND RESPONSE TO TREATMENT
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)“…Abstract Glioblastoma (GBM) is the most common and aggressive brain cancer, with a treatment regimen that has remained disappointingly unaltered for the last…”
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