Search Results - "Hassler, Melanie R"

Micropapillary Urothelial Carcinoma of the Bladder: A Systematic Review and Meta-analysis of Disease Characteristics and Treatment Outcomes by Abufaraj, Mohammad, Foerster, Beat, Schernhammer, Eva, Moschini, Marco, Kimura, Shoji, Hassler, Melanie R., Preston, Mark A., Karakiewicz, Pierre I., Remzi, Mesut, Shariat, Shahrokh F.

“…The optimal treatment of urothelial bladder cancer (UBC) with micropapillary (MP) variant histology is not clear. To review the current literature on disease…”
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Blood-Based Biomarkers as Prognostic Factors of Recurrent Disease after Radical Cystectomy: A Systematic Review and Meta-Analysis by Ofner, Heidemarie, Laukhtina, Ekaterina, Hassler, Melanie R, Shariat, Shahrokh F

“…Survival outcomes after radical cystectomy (RC) for bladder cancer (BCa) have not improved in recent decades; nevertheless, RC remains the standard treatment…”
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Molecular Characterization of Upper Tract Urothelial Carcinoma in the Era of Next-generation Sequencing: A Systematic Review of the Current Literature by Hassler, Melanie R., Bray, Freddie, Catto, James W.F., Grollman, Arthur P., Hartmann, Arndt, Margulis, Vitaly, Matin, Surena F., Roupret, Morgan, Sfakianos, John P., Shariat, Shahrokh F., Faltas, Bishoy M.

“…While upper tract urothelial carcinoma (UTUC) share histological appearance with bladder cancer (BC), the former has differences in etiology and clinical…”
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Epigenomics of cancer – emerging new concepts by Hassler, Melanie R., Egger, Gerda

“…The complexity of the mammalian genome is regulated by heritable epigenetic mechanisms, which provide the basis for differentiation, development and cellular…”
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Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling by Hassler, Melanie R., Pulverer, Walter, Lakshminarasimhan, Ranjani, Redl, Elisa, Hacker, Julia, Garland, Gavin D., Merkel, Olaf, Schiefer, Ana-Iris, Simonitsch-Klupp, Ingrid, Kenner, Lukas, Weisenberger, Daniel J., Weinhaeusel, Andreas, Turner, Suzanne D., Egger, Gerda

“…Aberrant DNA methylation patterns in malignant cells allow insight into tumor evolution and development and can be used for disease classification. Here, we…”
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Brain-derived neurotrophic factor (BDNF)—Epigenetic regulation in unipolar and bipolar affective disorder by Carlberg, Laura, Scheibelreiter, Janine, Hassler, Melanie R, Schloegelhofer, Monika, Schmoeger, Michaela, Ludwig, Birgit, Kasper, Siegfried, Aschauer, Harald, Egger, Gerda, Schosser, Alexandra

“…Abstract Background Alterations of brain-derived neurotrophic factor (BDNF) DNA methylation at specific BDNF promoters and corresponding gene expressions are…”
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Evaluation of APOBEC3 expression as prognostic marker in squamous cell carcinoma of the penis by Trimmel, Bettina, Oszwald, Andre, Diemand, Christoph, Ertl, Iris E., Lemberger, Ursula, Bruchbacher, Andreas, Brettner, Robert, Korn, Stephan, Resch, Irene, Comperat, Eva, Shariat, Shahrokh F., Hassler, Melanie R.

“…Squamous cell carcinoma of the penis (PSC) is a rare disease with limited information on the molecular events leading to malignant transformation. In a third…”
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Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)⁺ and ALK⁻ anaplastic large-cell lymphoma by Merkel, Olaf, Hamacher, Frank, Laimer, Daniela, Sifft, Eveline, Trajanoski, Zlatko, Scheideler, Marcel, Egger, Gerda, Hassler, Melanie R, Thallinger, Christiane, Schmatz, Ana, Turner, Suzanne D, Greil, Richard, Kenner, Lukas

“…Aberrant anaplastic lymphoma kinase (ALK) expression is a defining feature of many human cancers and was identified first in anaplastic large-cell lymphoma…”
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Identification of tumor tissue-derived DNA methylation biomarkers for the detection and therapy response evaluation of metastatic castration resistant prostate cancer in liquid biopsies by Dillinger, Thomas, Sheibani-Tezerji, Raheleh, Pulverer, Walter, Stelzer, Ines, Hassler, Melanie R, Scheibelreiter, Janine, Pérez Malla, Carlos Uziel, Kuroll, Madeleine, Domazet, Sandra, Redl, Elisa, Ely, Sarah, Brezina, Stefanie, Tiefenbacher, Andreas, Rebhan, Katharina, Hübner, Nicolai, Grubmüller, Bernhard, Mitterhauser, Markus, Hacker, Marcus, Weinhaeusel, Andreas, Simon, Judit, Zeitlinger, Markus, Gsur, Andrea, Kramer, Gero, Shariat, Shahrokh F, Kenner, Lukas, Egger, Gerda

“…Aside from genetic alterations, epigenetic tumor-specific changes including DNA methylation are measurable in ctDNA and CTCs and their potential as diagnostic,…”
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The mitochondrial carrier Rim2 co-imports pyrimidine nucleotides and iron by Froschauer, Elisabeth M, Rietzschel, Nicole, Hassler, Melanie R, Binder, Markus, Schweyen, Rudolf J, Lill, Roland, Mühlenhoff, Ulrich, Wiesenberger, Gerlinde

“…Mitochondrial iron uptake is of key importance both for organelle function and cellular iron homoeostasis. The mitochondrial carrier family members Mrs3 and…”
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An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer by Xylinas, Evanguelos, Hassler, Melanie R, Zhuang, Dazhong, Krzywinski, Martin, Erdem, Zeynep, Robinson, Brian D, Elemento, Olivier, Clozel, Thomas, Shariat, Shahrokh F

“…Bladder cancer is among the five most common cancers diagnosed in the Western world and causes significant mortality and morbidity rates in affected patients…”
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Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma by Zrimšek, Maša, Kuchaříková, Hana, Draganić, Kristina, Dobrovolná, Pavlína, Heiss Spornberger, Verena, Winkelmayer, Lisa, Hassler, Melanie, Lochmanová, Gabriela, Zdráhal, Zbyněk, Egger, Gerda

“…Histone deacetylases (HDACs) target acetylated lysine residues in histone and non-histone proteins. HDACs are implicated in the regulation of genomic…”
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The effect of HER2 status on oncological outcomes of patients with invasive bladder cancer by Soria, Francesco, MD, Moschini, Marco, MD, Haitel, Andrea, MD, Wirth, Gregory J., MD, Gust, Kilian M., MD, Briganti, Alberto, MD, Rouprêt, Morgan, M.D., Ph.D, Klatte, Tobias, M.D, Hassler, Melanie R., Ph.D, Karakiewicz, Pierre I., M.D, Shariat, Shahrokh F., Ph.D

“…Abstract Purpose The aim of this study was to evaluate the overexpression of human epidermal growth factor receptor 2 (HER2) in patients with bladder cancer…”
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Discovery of Molecular DNA Methylation-Based Biomarkers through Genome-Wide Analysis of Response Patterns to BCG for Bladder Cancer by Ilijazi, Dafina, Pulverer, Walter, Ertl, Iris E, Lemberger, Ursula, Kimura, Shoji, Abufaraj, Mohammad, D'Andrea, David, Pradere, Benjamin, Bruchbacher, Andreas, Graf, Anna, Soria, Francesco, Susani, Martin, Haitel, Andrea, Molinaro, Luca, Pycha, Armin, Comploj, Evi, Pabinger, Stephan, Weinhäusel, Andreas, Egger, Gerda, Shariat, Shahrokh F, Hassler, Melanie R

“…Bacillus Calmette-Guérin (BCG) immunotherapy, the standard adjuvant intravesical therapy for some intermediate and most high-risk non-muscle invasive bladder…”
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Single-lesion Prostate-specific Membrane Antigen Protein Expression (PSMA) and Response to [177Lu]-PSMA-ligand Therapy in Patients with Castration-resistant Prostate Cancer by Stangl-Kremser, Judith, Rasul, Sazan, Tosoian, Jeffrey J., Salami, Simpa S., Zaslavsky, Alexander, Udager, Aaron, Mazal, Peter, Kain, Renate, Comperat, Eva, Hacker, Marcus, Haug, Alexander, Mitterhauser, Markus, Pozo-Salido, Carmen, Steinbach, Christina, Hassler, Melanie R., Kramer, Gero, Shariat, Shahrokh F., Palapattu, Ganesh S.

“…Initial reports of a clinical response in patients treated with the radioligand [177Lu]-PSMA-617 for castration-resistant prostate cancer (CRPC) are promising,…”
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Caveolin-1 as prognostic factor of disease recurrence and survival in patients treated with radical cystectomy for bladder cancer by Soria, Francesco, M.D, Lucca, Ilaria, M.D, Moschini, Marco, M.D, Mathieu, Romain, M.D, Rouprêt, Morgan, M.D, Karakiewicz, Pierre I., M.D, Briganti, Alberto, M.D, Rink, Michael, M.D, Gust, Kilian M., M.D, Hassler, Melanie R., M.D, Foerster, Beat, M.D, Abufarraj, Mohammad, M.D, Haitel, Andrea, M.D, Klatte, Tobias, M.D, Shariat, Shahrokh F., M.D

“…Abstract Purpose Overexpression of Caveolin-1 has been associated with cancer growth, migration, and metastases in several malignancies, but only few data are…”
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Re: Lymph Node Colonization Induces Tumor-immune Tolerance To Promote Distant Metastasis by Hassler, Melanie R., Shariat, Shahrokh F.

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Molecular intricacies of upper tract urothelial carcinoma and their relevance for therapy considerations by Berndl, Florian, Hassler, Melanie R.

“…The aim of this study was to give an overview of molecular alterations in upper tract urothelial carcinomas (UTUCs) and to discuss them in the context of…”
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Editorial: genetics in urology by Hassler, Melanie R., Lawrentschuk, Nathan

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A retrospective cross-sectional study on district-based socioeconomic status and prostate cancer diagnosis by Yurdakul, Ozan, Tuncel, Altug, Hassler, Melanie R, Oberneder, Katharina, Gamez, David V, Remzi, Mesut

“…Socioeconomic disparities have been linked to delayed prostate cancer diagnosis and poorer outcomes in various countries. This study aims to evaluate the…”
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