Search Results - "Hassett, Matthew R"

In vitro growth competition experiments that suggest consequences of the substandard artemisinin epidemic that may be accelerating drug resistance in P. falciparum malaria by Hassett, Matthew R, Roepe, Paul D

“…Over the past decade, artemisinin (ART)-combination therapies (ACTs) have shown declining efficacy within Southeast Asia (SEA). These resistance-like phenomena…”
Get full text

saRNA vaccine expressing membrane-anchored RBD elicits broad and durable immunity against SARS-CoV-2 variants of concern by Komori, Mai, Nogimori, Takuto, Morey, Amber L., Sekida, Takashi, Ishimoto, Keiko, Hassett, Matthew R., Masuta, Yuji, Ode, Hirotaka, Tamura, Tomokazu, Suzuki, Rigel, Alexander, Jeff, Kido, Yasutoshi, Matsuda, Kenta, Fukuhara, Takasuke, Iwatani, Yasumasa, Yamamoto, Takuya, Smith, Jonathan F., Akahata, Wataru

“…Several vaccines have been widely used to counteract the global pandemic caused by SARS-CoV-2. However, due to the rapid emergence of SARS-CoV-2 variants of…”
Get full text

Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology by Gabryszewski, Stanislaw J, Dhingra, Satish K, Combrinck, Jill M, Lewis, Ian A, Callaghan, Paul S, Hassett, Matthew R, Siriwardana, Amila, Henrich, Philipp P, Lee, Andrew H, Gnädig, Nina F, Musset, Lise, Llinás, Manuel, Egan, Timothy J, Roepe, Paul D, Fidock, David A

“…Southeast Asia is an epicenter of multidrug-resistant Plasmodium falciparum strains. Selective pressures on the subcontinent have recurrently produced several…”
Get full text

Heterologous Expression, Purification, and Functional Analysis of Plasmodium falciparum Phosphatidylinositol 3′-Kinase by Hassett, Matthew R, Sternberg, Anna R, Riegel, Bryce E, Thomas, Craig J, Roepe, Paul D

“…The Plasmodium falciparum malarial parasite genome appears to encode one and only one phosphatidylinositol 3′-kinase (PI3K), and sequence analysis suggests…”
Get full text

Origin and Spread of Evolving Artemisinin-Resistant Plasmodium falciparum Malarial Parasites in Southeast Asia by Hassett, Matthew R, Roepe, Paul D

“…In this review, we provide an epidemiological history of the emergence and ongoing spread of evolving artemisinin resistance (ARTR). Southeast Asia has been…”
Get full text

Attitudes toward Concealed Carry of Firearms on Campus: A Systematic Review of the Literature by Hassett, Matthew R., Kim, Bitna, Seo, Chunghyeon

“…Gun control is a highly debated and divisive social issue. In recent years, this issue has been thrust into the academic arena with the advent of campus carry…”
Get full text

Campus Carry Attitudes Revisited: Variations within the University Campus Community by Hassett, Matthew R., Kim, Bitna

“…This study examined attitudes toward campus carry - a policy that would permit individuals to carry concealed firearms on a university's grounds if they…”
Get full text

PIK-ing New Malaria Chemotherapy by Hassett, Matthew R., Roepe, Paul D.

“…Phosphatidylinositol (PI) kinases (PIKs) regulate cell proliferation, survival, membrane trafficking, and other processes. PIK classes are distinguished by…”
Get full text

Functional Comparison of 45 Naturally Occurring Isoforms of the Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) by Callaghan, Paul S, Hassett, Matthew R, Roepe, Paul D

“…At least 53 distinct isoforms of Plasmodium falciparum chloroquine resistance transporter (PfCRT) protein are expressed in strains or isolates of P. falciparum…”
Get full text

Attitudes toward concealed carry on campus: results from a nationwide survey of criminologists by Hassett, Matthew R., Kim, Bitna

“…A small but growing number of studies has explored the attitudes about this campus carry policy held by campus community members. The current study expands on…”
Get full text

Inhibition of Human Class I vs Class III Phosphatidylinositol 3′-Kinases by Hassett, Matthew R, Sternberg, Anna R, Roepe, Paul D

“…Most investigations of phosphatidylinositol 3′-kinase (PI3K) drug inhibition have been via assays based on ADP appearance or ATP consumption (e.g., Liu, Q., et…”
Get full text

Analysis of Plasmodium vivax Chloroquine Resistance Transporter Mutant Isoforms by Hassett, Matthew R, Riegel, Bryce E, Callaghan, Paul S, Roepe, Paul D

“…Chloroquine (CQ) resistance (CQR) in Plasmodium falciparum malaria is widespread and has limited the use of CQ in many regions of the globe. Malaria caused by…”
Get full text

Female-Perpetrated Homicide in South Korea: A Homicide Typology by Kim, Bitna, Gerber, Jurg, Kim, Yeonghee, Hassett, Matthew R.

“…Using cluster analysis, the current study examined the extent to which distinct types of homicides are present using national data of female-perpetrated…”
Get full text

Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiology by Callaghan, Paul S, Siriwardana, Amila, Hassett, Matthew R, Roepe, Paul D

“…Recent work has perfected yeast-based methods for measuring drug transport by the Plasmodium falciparum chloroquine (CQ) resistance transporter (PfCRT). The…”
Get full text

Attitudes Regarding the Concealed Carry of Firearms on University Campuses by Hassett, Matthew R

“…Policies permitting the concealed carry of firearms on campus grounds (“Campus Carry”) continue to be implemented at universities across the United States. At…”
Get full text