Search Results - "Hasselby, Jane P"

Abnormal islet sphingolipid metabolism in type 1 diabetes by Holm, Laurits J., Krogvold, Lars, Hasselby, Jane P., Kaur, Simranjeet, Claessens, Laura A., Russell, Mark A., Mathews, Clayton E., Hanssen, Kristian F., Morgan, Noel G., Koeleman, Bobby P. C., Roep, Bart O., Gerling, Ivan C., Pociot, Flemming, Dahl-Jørgensen, Knut, Buschard, Karsten

“…Aims/hypothesis Sphingolipids play important roles in beta cell physiology, by regulating proinsulin folding and insulin secretion and in controlling…”
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Mode of delivery shapes gut colonization pattern and modulates regulatory immunity in mice by Hansen, Camilla H F, Andersen, Line S F, Krych, Lukasz, Metzdorff, Stine B, Hasselby, Jane P, Skov, Søren, Nielsen, Dennis S, Buschard, Karsten, Hansen, Lars H, Hansen, Axel K

“…Delivery mode has been associated with long-term changes in gut microbiota composition and more recently also with changes in the immune system. This has…”
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New Pathogenic Germline Variants in Very Early Onset and Familial Colorectal Cancer Patients by Djursby, Malene, Madsen, Majbritt B., Frederiksen, Jane H., Berchtold, Lukas A., Therkildsen, Christina, Willemoe, Gro L., Hasselby, Jane P., Wikman, Friedrik, Okkels, Henrik, Skytte, Anne-Bine, Nilbert, Mef, Wadt, Karin, Gerdes, Anne-Marie, van Overeem Hansen, Thomas

“…A genetic diagnosis facilitates personalized cancer treatment and clinical care of relatives at risk, however, although 25% of colorectal cancer cases are…”
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Prognostic value of circulating proteins in patients undergoing surgery for pancreatic cancer by Lindgaard, Sidsel C., Sztupinszki, Zsófia, Maag, Emil, Hansen, Carsten P., Chen, Inna M., Johansen, Astrid Z., Hasselby, Jane P., Bojesen, Stig E., Nielsen, Dorte, Johansen, Julia S.

“…Background Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death. Less than 20% of patients are diagnosed with resectable…”
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Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy by Mortensen, Rasmus Erik Johansson, Holmström, Morten Orebo, Lisle, Thomas Landkildehus, Hasselby, Jane P, Willemoe, Gro L, Met, Özcan, Marie Svane, Inge, Johansen, Julia, Nielsen, Dorte L, Chen, Inna M, Andersen, Mads Hald

“…BackgroundCirculating transforming growth factor-β (TGF-β)-specific T cells that recognize TGF-β-expressing immune regulatory cells have been described in…”
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Goblet cell carcinoids: characteristics of a Danish cohort of 83 patients by Olsen, Ingrid Holst, Holt, Nanna, Langer, Seppo W, Hasselby, Jane P, Grønbæk, Henning, Hillingsø, Jens, Mahmoud, Masti, Ladekarl, Morten, Iversen, Lene H, Kjær, Andreas, Federspiel, Birgitte H, Knigge, Ulrich

“…Appendiceal goblet cell carcinoids (GCCs) exhibit neuroendocrine and adenocarcinoma features. Analysis of demography, pathology, prognostic markers, treatment…”
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The incidence of free peritoneal tumor cells before and after neoadjuvant chemotherapy in gastroesophageal junction cancer by Strandby, Rune, Svendsen, Lars, Ambrus, Rikard, Rostved, Andreas, Hasselby, Jane, Achiam, Michael

“…Context: The utility of peritoneal washing cytology in patients with gastroesophageal junction cancer has not been thoroughly evaluated. Aims: The study aimed…”
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Copenhagen Prospective Personalized Oncology (CoPPO)-Clinical Utility of Using Molecular Profiling to Select Patients to Phase I Trials by Tuxen, Ida Viller, Rohrberg, Kristoffer Staal, Oestrup, Olga, Ahlborn, Lise Barlebo, Schmidt, Ane Yde, Spanggaard, Iben, Hasselby, Jane P, Santoni-Rugiu, Eric, Yde, Christina Westmose, Mau-Sørensen, Morten, Nielsen, Finn Cilius, Lassen, Ulrik

“…We evaluated the clinical benefit of tumor molecular profiling to select treatment in the phase I setting. Patients with advanced solid cancers and exhausted…”
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Randomized Phase II Study of Nivolumab With or Without Ipilimumab Combined With Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC) by Chen, Inna M, Johansen, Julia S, Theile, Susann, Hjaltelin, Jessica X, Novitski, Sif I, Brunak, Søren, Hasselby, Jane P, Willemoe, Gro L, Lorentzen, Torben, Madsen, Kasper, Jensen, Benny V, Wilken, Eva E, Geertsen, Poul, Behrens, Claus, Nolsoe, Christian, Hermann, Kirstine L, Svane, Inge Marie, Nielsen, Dorte

“…To evaluate the clinical benefit of nivolumab with or without ipilimumab in combination with stereotactic body radiotherapy (SBRT) in patients with refractory…”
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Fenofibrate increases very-long-chain sphingolipids and improves blood glucose homeostasis in NOD mice by Holm, Laurits J., Haupt-Jorgensen, Martin, Giacobini, Jano D., Hasselby, Jane P., Bilgin, Mesut, Buschard, Karsten

“…Aims/hypothesis Sphingolipid metabolism regulates beta cell biology and inflammation and is abnormal at the onset of type 1 diabetes. Fenofibrate, a regulator…”
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Clinical value of serum hyaluronan and propeptide of type III collagen in patients with pancreatic cancer by Chen, Inna M., Willumsen, Nicholas, Dehlendorff, Christian, Johansen, Astrid Z., Jensen, Benny V., Hansen, Carsten P., Hasselby, Jane P., Bojesen, Stig E., Pfeiffer, Per, Nielsen, Svend E., Holländer, Niels H., Yilmaz, Mette K., Karsdal, Morten, Johansen, Julia S.

“…Hyaluronan (HA) and collagen are highly expressed in pancreatic cancer (PC) stroma. HA and collagen accumulation increase tumor interstitial fluid pressure,…”
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Phase 2 study of ipilimumab, nivolumab, and tocilizumab combined with stereotactic body radiotherapy in patients with refractory pancreatic cancer (TRIPLE-R) by Chen, Inna M., Donia, Marco, Chamberlain, Christopher A., Jensen, Agnete W.P., Draghi, Arianna, Theile, Susann, Madsen, Kasper, Hasselby, Jane P., Toxværd, Anders, Høgdall, Estrid, Lorentzen, Torben, Wilken, Eva E., Geertsen, Poul, Svane, Inge M., Johansen, Julia S., Nielsen, Dorte

“…Interleukin-6 blockade and radiation combined with immunotherapy may modulate the tumour microenvironment to overcome immune resistance. We assessed the…”
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Nivolumab With or Without Ipilimumab Combined with Stereotactic Body Radiotherapy in patients with Metastatic Biliary Tract Cancer: A Randomized Phase 2 Study by Markussen, Alice, Johansen, Julia S, Larsen, Finn O, Theile, Susann, Hasselby, Jane P, Willemoe, Gro L, Lorentzen, Torben, Madsen, Kasper, Høgdall, Estrid, Poulsen, Tim S, Wilken, Eva E, Geertsen, Poul, Behrens, Claus P, Svane, Inge M, Nielsen, Dorte, Chen, Inna M

“…Evaluate the clinical benefits of nivolumab with/without ipilimumab combined with stereotactic body radiotherapy (SBRT) in patients with pretreated metastatic…”
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Circulating Protein Biomarkers for Use in Pancreatic Ductal Adenocarcinoma Identification by Lindgaard, Sidsel C, Sztupinszki, Zsófia, Maag, Emil, Chen, Inna M, Johansen, Astrid Z, Jensen, Benny V, Bojesen, Stig E, Nielsen, Dorte L, Hansen, Carsten P, Hasselby, Jane P, Nielsen, Kaspar R, Szallasi, Zoltan, Johansen, Julia S

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. Most patients are diagnosed at an advanced stage where curative surgery is not…”
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Prognostic value of margin clearance in total and distal pancreatectomy specimens with pancreatic ductal adenocarcinoma in a Danish population-based nationwide study by Aaquist, Trine, Fristrup, Claus W., Hasselby, Jane P., Hamilton-Dutoit, Stephen, Eld, Mikkel, Pfeiffer, Per, Mortensen, Michael B., Detlefsen, Sönke

“…The prognostic role of resection margin status following total (TP) and distal (DP) pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) is…”
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Prognostic importance of margin clearance in ampullary adenocarcinoma following pancreaticoduodenectomy in a Danish population-based nationwide study by Aaquist, Trine, Fristrup, Claus W, Hasselby, Jane P, Hamilton-Dutoit, Stephen, Eld, Mikkel, Pfeiffer, Per, Mortensen, Michael B, Detlefsen, Sönke

“…In this Danish nationwide population-based study, we evaluated the prognostically relevant minimum tumour-free margin width following pancreaticoduodenectomy…”
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Prognostic significance of margin clearance in pancreaticoduodenectomy specimens with pancreatic ductal adenocarcinoma in a Danish population-based nationwide study by Aaquist, Trine, Fristrup, Claus W., Hasselby, Jane P., Hamilton-Dutoit, Stephen, Eld, Mikkel, Pfeiffer, Per, Mortensen, Michael B., Detlefsen, Sönke

“…In this nationwide population-based cohort study, we investigated the overall minimum margin width that is independently associated with improved survival…”
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Pre-treatment serum vitamin D deficiency is associated with increased inflammatory biomarkers and short overall survival in patients with pancreatic cancer by Rasmussen, Louise S., Yilmaz, Mette K., Falkmer, Ursula G., Poulsen, Laurids Ø., Bøgsted, Martin, Christensen, Heidi S., Bojesen, Stig E., Jensen, Benny V., Chen, Inna M., Johansen, Astrid Z., Hansen, Carsten P., Hasselby, Jane P., Holländer, Niels, Nielsen, Svend E., Andersen, Fahimeh, Bjerregaard, Jon K., Pfeiffer, Per, Johansen, Julia S.

“…Vitamin D deficiency and inflammation are associated with increased mortality. We investigated the relationship between pre-treatment serum vitamin D levels,…”
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Immunohistochemical assessment of glucagon‐like peptide 1 receptor (GLP‐1R) expression in the pancreas of patients with type 2 diabetes by Kirk, Rikke K., Pyke, Charles, von Herrath, Matthias G., Hasselby, Jane P., Pedersen, Lars, Mortensen, Pia G., Knudsen, Lotte B., Coppieters, Ken

“…Aims Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone which stimulates insulin release and inhibits glucagon secretion from the pancreas in a…”
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Response to the letter entitled: Re: Pre-treatment serum vitamin D deficiency is associated with increased inflammatory biomarkers and short overall survival in patients with pancreatic cancer: Analysis of the prognostic effect of serum vitamin D on pancreatic cancer: Several confounders by Rasmussen, Louise S., Yilmaz, Mette K., Falkmer, Ursula G., Poulsen, Laurids Ø., Bøgsted, Martin, Christensen, Heidi S., Bojesen, Stig E., Jensen, Benny V., Chen, Inna M., Johansen, Astrid Z., Hansen, Carsten P., Hasselby, Jane P., Holländer, Niels, Nielsen, Svend E., Andersen, Fahimeh, Bjerregaard, Jon K., Pfeiffer, Per, Johansen, Julia S.

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