Search Results - "Hassawi, Mona"
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Inability of HOXB4 to enhance self-renewal of malignant B cells: Favorable profile for the expansion of autologous hematopoietic stem cells
Published in Experimental hematology (01-07-2014)“…Leukemic stem cells share self-renewal properties and slow proliferation with hematopoietic stem cells. Based on expression signatures, it has been suggested…”
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Paralog 4 HOX Genes HOXA4 and HOXB4 Expand Pro-B Cells in Vitro
Published in Blood (18-11-2011)“…Abstract 1299 HOX genes are known for their involvement in self-renewal of normal and malignant hematopoietic stem cells (HSC). Enforced expression of HOXB4…”
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Abstract 5538: Development of HDACi resistance in DLBCL leads to a switch in subtype towards a more differentiated B-cell and is associated with increased sensitivity to proteasome inhibition
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Diffuse Large B Cell Lymhoma (DLBCL) is a highly heterogeneous disease in terms of clinical presentation, cell morphology, molecular characteristics and…”
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Hoxa9 collaborates with E2A‐PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression
Published in Developmental dynamics (01-01-2014)“…Background: The fusion protein E2A‐PBX1 induces pediatric B cell leukemia in human. Previously, we reported oncogenic interactions between homeobox (Hox) genes…”
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