Search Results - "Hassani, Leila"
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Auto-associative amphiphilic polysaccharides as drug delivery systems
Published in Drug discovery today (01-06-2012)“…Self-assembly of amphiphilic polysaccharides provides a positive outlook for drug delivery systems without the need for solvents or surfactants. Various…”
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FastKnock: an efficient next-generation approach to identify all knockout strategies for strain optimization
Published in Microbial cell factories (29-01-2024)“…Overproduction of desired native or nonnative biochemical(s) in (micro)organisms can be achieved through metabolic engineering. Appropriate rewiring of cell…”
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Modification of Lysine Residues of Horseradish Peroxidase and Its Effect on Stability and Structure of the Enzyme
Published in Applied biochemistry and biotechnology (01-04-2014)“…Biotechnology is consistently seeking improved enzyme stability. Enzymes have great properties, although their marginal stability limits their applications…”
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Comparison of the Prophylactic Effect of Propofol, Dexamethasone and Ondansetron on Post-Operative Nausea and Vomiting in Elective Cesarean Section Under Spinal Anesthesia
Published in Acta medica Iranica (2021)“…Nausea, and vomiting are common complications in women undergoing cesarean section with spinal anesthesia. This study aimed to compare the propofol,…”
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Relationship between LncRNA THRIL expression controlling TNF-alpha pathway in glioblastoma cell line under temozolomide treatment
Published in Majallah-i Danishkadah-'i Pizishki (01-10-2018)“…Background: Glioma is one of the most common and deadliest primary malignant tumors in the brain. A large part of the gene expression products are non-coding…”
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Evaluation of the Comparative Effectiveness of Three Therapeutic Drug Regimens in the Treatment of Medication Overuse Headache in the Patients with Headache
Published in Majallāh-i ʻilmī-i Dānishgāh-i ʻUlūm-i Pizishkī-i Kurdistān (01-07-2020)“…Background and Aim: Medication overuse headache (MOH) is the second leading cause of chronic headaches. This study aimed to compare the efficacy of three…”
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Horseradish peroxidase thermostabilization: The combinatorial effects of the surface modification and the polyols
Published in Enzyme and microbial technology (01-01-2006)“…Horseradish peroxidase is an important heme-containing plant enzyme with enormous medical diagnostic, biosensing, bioremediation and biotechnological…”
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Chemical modification of Horseradish peroxidase with carboxylic anhydrides: Effect of negative charge and hydrophilicity of the modifiers on thermal stability
Published in Journal of molecular catalysis. B, Enzymatic (01-08-2012)“…[Display omitted] ► Modification of HRP with the carboxylic anhydrides leads to its thermal stability. ► The higher number of carboxylic groups leads to higher…”
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Interaction of gallium, indium, and vanadyl curcumin complexes with hen egg-white lysozyme (HEWL): Mechanistic aspects and evaluation of antiamyloidogenic activity
Published in Biochemical and biophysical research communications (08-01-2024)“…Many proteins and peptides can aggregate into amyloid fibrils with high-ordered and cross-β rich structure characteristics. Amyloid deposition is a common…”
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Physicochemical studies on the structural stability of the HIV-1 vaccine candidate recombinant Tat protein
Published in International journal of biological macromolecules (01-12-2020)“…HIV-1 transactivator of transcription protein is one of the most promising AIDS vaccine candidates and plays central roles in the virus life cycle and…”
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The Effect of Chemical Modification with Pyromellitic Anhydride on Structure, Function, and Thermal Stability of Horseradish Peroxidase
Published in Applied biochemistry and biotechnology (01-06-2012)“…The stability of enzymes remains a critical issue in biotechnology. Compared with the strategies for obtaining stable enzymes, chemical modification is a…”
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Toward Escherichia coli bacteria-machine for water-oxidation reaction at neutral conditions: Using Ruthenium Red
Published in International journal of hydrogen energy (29-01-2023)“…Water splitting into hydrogen and oxygen is a promising method for storing sustainable but intermittent energies. Ruthenium compounds are promising for the…”
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The optimization of resilience and sustainability using mathematical programming models and metaheuristic algorithms
Published in Journal of cleaner production (10-08-2019)“…The present study attempts to posit a suitable strategy for the optimal production with the maximum resilience and sustainability in the industrial dairy…”
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Inhibition of amyloid fibrillation of lysozyme by bisdemethoxycurcumin and diacetylbisdemethoxycurcumin
Published in Biophysical chemistry (01-04-2018)“…Amyloid deposition, arising from the fibrillogenesis of proteins in organs and tissues of the body, causes several neurodegenerative disorders. One therapeutic…”
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Spectroscopic investigation on the interaction of copper porphyrazines and phthalocyanine with human telomeric G-quadruplex DNA
Published in Biophysical chemistry (01-03-2014)“…The G-quadruplex DNA is a novel target for anticancer drug discovery and many scientific groups are investigating interaction of small molecules with…”
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Investigating the effect of gallium curcumin and gallium diacetylcurcumin complexes on the structure, function and oxidative stability of the peroxidase enzyme and their anticancer and antibacterial activities
Published in Journal of biological inorganic chemistry (01-10-2015)“…Curcumin has a wide spectrum of biological and pharmacological activities including anti-inflammatory, antioxidant, antiproliferative, antimicrobial and…”
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The biological effects of vanadyl curcumin and vanadyl diacetylcurcumin complexes: the effect on structure, function and oxidative stability of the peroxidase enzyme, antibacterial activity and cytotoxic effect
Published in Journal of enzyme inhibition and medicinal chemistry (01-11-2016)“…Curcumin has multiple pharmacological effects, but it has poor stability. Complexation of curcumin with metals improves its stability. Here, the effects of…”
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An evolution-based designing and characterization of mutants of cyclomaltodextrinase: Molecular modeling and spectroscopic studies
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-04-2020)“…Cyclomaltodextrinase (CDase) is a member of the alpha-amylase family GH13, the subfamily GH13_20. In addition to CDase and neopullulanase, this subfamily also…”
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Interaction of aurein 1.2 and its analogue with DPPC lipid bilayer
Published in Journal of biological physics (01-03-2017)“…Antibacterial peptides have potential as novel therapeutic agents for bacterial infections. Aurein 1.2 is one of the smallest antibacterial peptides extracted…”
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Step-wise addition of disulfide bridge in firefly luciferase controls color shift through a flexible loop: a thermodynamic perspective
Published in Photochemical & photobiological sciences (01-02-2013)“…Multi-color bioluminescence is developed using the introduction of single/double disulfide bridges in firefly luciferase. The bioluminescence reaction, which…”
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