Search Results - "Hassanein, Emad M."

Acetovanillone augmented the cardioprotective effect of carvedilol against cadmium-induced heart injury via suppression of oxidative stress and inflammation signaling pathways by Hassanein, Emad H. M., Bakr, Adel G., El-Shoura, Ehab A. M., Ahmed, Lamiaa Khalaf, Ali, Fares E. M.

“…Cardiac toxicity is a public health issue that can be caused by both environmental and occupational exposures. The current study aimed to investigate the…”
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The antimicrobial, antibiofilm, and wound healing properties of ethyl acetate crude extract of an endophytic fungus Paecilomyces sp. (AUMC 15510) in earthworm model by Salem, Shimaa H., El-Maraghy, Saad S., Abdel-Mallek, Ahmed Y., Abdel-Rahman, Mohamed A. A., Hassanein, Emad H. M., Al-Bedak, Osama A., El-Aziz, Fatma El-Zahraa A. Abd

“…The endophytic fungus Paecilomyces sp. (AUMC 15510) was isolated from healthy stem samples of the Egyptian medicinal plant Cornulaca monacantha . We used GC–MS…”
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Oxidative Stress, Inflammation, and Altered Lymphocyte E-NTPDase Are Implicated in Acute Dyslipidemia in Rats: Protective Role of Arbutin by Alruhaimi, Reem S, Hussein, Omnia E, Alnasser, Sulaiman M, Germoush, Mousa O, Alotaibi, Meshal, Hassanein, Emad H M, El Mohtadi, Mohamed, Mahmoud, Ayman M

“…Dyslipidemia is frequently linked to various disorders, and its clinical relevance is now recognized. The role of inflammation and oxidative stress (OS) in…”
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Targeting SIRT1/FoxO3a/Nrf2 and PI3K/AKT Pathways with Rebamipide Attenuates Acetic Acid-Induced Colitis in Rats by Abdel-Fattah, Maha M, Hassanein, Emad H M, Sayed, Ahmed M, Alsufyani, Shuruq E, El-Sheikh, Azza A K, Arab, Hany H, Mohamed, Wafaa R

“…Rebamipide is a quinolone derivative that has been commonly used for the treatment of gastric and duodenal ulcers. However, the molecular mechanisms of…”
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Candesartan Attenuates Cisplatin-Induced Lung Injury by Modulating Oxidative Stress, Inflammation, and TLR-4/NF-κB, JAK1/STAT3, and Nrf2/HO-1 Signaling by Atwa, Ahmed M, Abd El-Ghafar, Omnia A. M, Hassanein, Emad H. M, Mahdi, Somya E, Sayed, Ghadir A, Alruhaimi, Reem S, Alqhtani, Haifa A, Alotaibi, Mohammed F, Mahmoud, Ayman M

“…Cisplatin (CIS) is an effective chemotherapeutic agent against different cancers. The use of CIS is associated with acute lung injury (ALI) and other adverse…”
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Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities by Hussein, Shaimaa, Mahmoud, Ayman M., Elgebaly, Hassan A., Hendawy, Omnia Magdy, Hassanein, Emad H. M., Moustafa, Shaima M. N., Alotaibi, Nasser F., Nassar, Amr M.

“…In this study, we used the aqueous extract of garlic tunicate leaf to reduce a mixture of equal amounts of ruthenium chloride, silver nitrate, and palladium…”
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Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway by Mahmoud, Ayman M., Hussein, Omnia E., Sayed, Ahmed M., Hassanein, Emad H. M.

“…The Keap1/Nrf2/ARE system is a central defensive mechanism against oxidative stress which plays a key role in the pathogenesis and progression of many…”
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Molecular mechanisms underlying methotrexate-induced intestinal injury and protective strategies by Ali, Gaber F., Hassanein, Emad H. M., Mohamed, Wafaa R.

“…Methotrexate (MTX) is a folic acid reductase inhibitor that manages various malignancies as well as immune-mediated inflammatory chronic diseases. Despite…”
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Umbelliferone ameliorates ulcerative colitis induced by acetic acid via modulation of TLR4/NF-κB-p65/iNOS and SIRT1/PPARγ signaling pathways in rats by Abdel-Wahab, Basel A., Alkahtani, Saad A., Alqahtani, Abdulsalam A., Hassanein, Emad H. M.

“…Ulcerative colitis (UC) is a common chronic, idiopathic inflammatory bowel disease associated with inflammatory perturbation and oxidative stress…”
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Pharmacological update of mirtazapine: a narrative literature review by Hassanein, Emad H. M., Althagafy, Hanan S., Baraka, Mohammad A., Abd-alhameed, Esraa K., Ibrahim, Islam M.

“…Mirtazapine (MTZ) is an antidepressant drug with an exceptional pharmacological profile. It also has an excellent safety and tolerability profile. The present…”
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Role of Nrf2/HO-1, PPAR-γ, and cytoglobin signals in the pathogenesis of methotrexate-induced testicular intoxication in rats and the protective effect of diacerein by Abdel-Reheim, Mustafa Ahmed, Ali, Gaber F., Hassanein, Emad H. M., Mohamed, Wafaa R.

“…Methotrexate (MTX) is an inhibitor of folic acid reductase used in managing a variety of malignancies. Testicular injury by MTX is one of its serious adverse…”
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Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-κB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways by Hassanein, Emad H. M., Ali, Fares E. M., Kozman, Magy R., Abd El-Ghafar, Omnia A. M.

“…Nephrotoxicity is the most common adverse effect of gentamicin (GNT). This study aimed to investigate the possible nephroprotective effect of umbelliferone…”
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Cadmium-induced lung injury is associated with oxidative stress, apoptosis, and altered SIRT1 and Nrf2/HO-1 signaling; protective role of the melatonin agonist agomelatine by Alruhaimi, Reem S., Hassanein, Emad H. M., Bin-Jumah, May N., Mahmoud, Ayman M.

“…Cadmium (Cd) is a hazardous heavy metal extensively employed in manufacturing polyvinyl chloride, batteries, and other industries. Acute lung injury has been…”
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Nifuroxazide attenuates indomethacin-induced renal injury by upregulating Nrf2/HO-1 and cytoglobin and suppressing NADPH-oxidase, NF-κB, and JAK-1/STAT3 signals by Hassanein, Emad H. M., Abdel-Reheim, Mustafa Ahmed, Althagafy, Hanan S., Hemeda, Mohamed S., Gad, Rania A., Abdel-Sattar, Asmaa Ramadan

“…Indomethacin (INDO) is an NSAID with remarkable efficacy and widespread utilization for alleviating pain. Nevertheless, renal function impairment is an adverse…”
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Baicalin and lung diseases by Sharawi, Zeina W., Ibrahim, Islam M., Abd-alhameed, Esraa K., Althagafy, Hanan S., Jaber, Fatima A., Harakeh, Steve, Hassanein, Emad H. M.

“…Studies focusing on natural products have been conducted worldwide, and the results suggest that their natural ingredients effectively treat a wide range of…”
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The promising antioxidant effects of lignans: Nrf2 activation comes into view by Hassanein, Emad H. M., Althagafy, Hanan S., Baraka, Mohammad A., Abd-alhameed, Esraa K., Ibrahim, Islam M., Abd El-Maksoud, Mostafa S., Mohamed, Nesma M., Ross, Samir A.

“…Lignans are biologically active compounds widely distributed, recognized, and identified in seeds, fruits, and vegetables. Lignans have several intriguing…”
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Flavonoids of Haloxylon salicornicum (Rimth) prevent cisplatin-induced acute kidney injury by modulating oxidative stress, inflammation, Nrf2, and SIRT1 by Ramadan, Shaymaa A., Kamel, Emadeldin M., Ewais, Madeha A., Khowailed, Akef A., Hassanein, Emad H. M., Mahmoud, Ayman M.

“…Cisplatin (CIS) is an effective chemotherapeutic drug used for the treatment of many types of cancers, but its use is associated with adverse effects…”
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Lansoprazole attenuates cyclophosphamide-induced cardiopulmonary injury by modulating redox-sensitive pathways and inflammation by Hassanein, Emad H. M., Kamel, Esam O., Gad-Elrab, Wail M., Ahmed, Mohammed A., Mohammedsaleh, Zuhair M., Ali, Fares E. M.

“…Cyclophosphamide (CPA) is a classical chemotherapeutic drug widely used as an anticancer and immunosuppressive agent. However, it is frequently associated with…”
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The protective effect of 7-hydroxycoumarin against cisplatin-induced liver injury is mediated via attenuation of oxidative stress and inflammation and upregulation of Nrf2/HO-1 pathway by Sami, Demiana H., Soliman, Ayman S., Khowailed, Akef A., Alruhaimi, Reem S., Hassanein, Emad H. M., Kamel, Emadeldin M., Mahmoud, Ayman M.

“…Cisplatin (CIS) is an effective chemotherapy against different solid cancers. However, the adverse effects, including hepatotoxicity, limit its clinical use…”
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Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence by Shalkami, Abdel-Gawad S., Hassanein, Emad H. M., Sayed, Ahmed M., Mohamed, Wafaa R., Khalaf, Marwa M., Hemeida, Ramadan A. M.

“…Chemotherapeutic drugs are used effectively to manage wide types of malignancies, but their therapeutic use is limited due to their associated hepatic…”
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