Search Results - "Hassan, Syed Shams Ul"

An Overview of the Mechanisms of Marine Fungi-Derived Anti-Inflammatory and Anti-Tumor Agents and their Novel Role in Drug Targeting by Shams Ul Hassan, Syed, Ishaq, Muhammad, Zhang, Wei-Dong, Jin, Hui-Zi

“…Marine fungi with their successful pharmacological effects were considered to be the treasure of ocean medicines concerning the striking ability of their…”
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Current status and future therapeutic perspectives of glioblastoma multiforme (GBM) therapy: A review by Anjum, Komal, Shagufta, Bibi Ibtesam, Abbas, Syed Qamar, Patel, Seema, Khan, Ishrat, Shah, Sayed Asmat Ali, Akhter, Najeeb, Hassan, Syed Shams ul

“…Abstract Glioblastoma multiforme (GBM) is the deadliest form of heterogeneous brain cancer. It affects an enormous number of patients every year and the…”
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Enhancing Therapeutic Efficacy of Donepezil by Combined Therapy: A Comprehensive Review by Rong, Xi, Jiang, Liwei, Qu, Meijie, Hassan, Syed Shams Ul, Liu, Zongchao

“…Combination therapy involving different therapeutic strategies mostly provides more rapid and effective results as compared to monotherapy in diverse areas of…”
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Computational Exploration of Anti-Cancer Potential of GUAIANE Dimers from Xylopia vielana by Targeting B-Raf Kinase Using Chemo-Informatics, Molecular Docking, and MD Simulation Studies by Shams Ul Hassan, Syed, Abbas, Syed Qamar, Hassan, Mubashir, Jin, Hui-Zi

“…Natural products from herbs are abundant and display powerful anti-cancer activities. In the current study, B-Raf kinase protein (PDB: 3OG7), a potent target…”
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Marine actinobacteria as a drug treasure house by Hassan, Syed Shams ul, Shaikh, Abdul Lateef

“…Abstract Marine actinobacteria have been considered as a gold mine with respect to great potential regarding their secondary metabolites. Most of the…”
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A Comprehensive In Silico Exploration of Pharmacological Properties, Bioactivities, Molecular Docking, and Anticancer Potential of Vieloplain F from Xylopia vielana Targeting B-Raf Kinase by Hassan, Syed Shams Ul, Abbas, Syed Qamar, Ali, Fawad, Ishaq, Muhammad, Bano, Iqra, Hassan, Mubashir, Jin, Hui-Zi, Bungau, Simona G

“…Compounds derived from plants have several anticancer properties. In the current study, one guaiane-type sesquiterpene dimer, vieloplain F, isolated from…”
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Stress Driven Discovery of Natural Products From Actinobacteria with Anti-Oxidant and Cytotoxic Activities Including Docking and ADMET Properties by Hassan, Syed Shams Ul, Muhammad, Ishaq, Abbas, Syed Qamar, Hassan, Mubashir, Majid, Muhammad, Jin, Hui-Zi, Bungau, Simona

“…Elicitation through abiotic stress, including chemical elicitors like heavy metals, is a new technique for drug discovery. In this research, the effect of…”
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Ferroptosis: A New Road towards Cancer Management by Bano, Iqra, Horky, Pavel, Abbas, Syed Qamar, Majid, Muhammad, Bilal, Akram Hafiz Muhammad, Ali, Fawad, Behl, Tapan, Hassan, Syed Shams Ul, Bungau, Simona

“…Ferroptosis is a recently described programmed cell death mechanism that is characterized by the buildup of iron (Fe)-dependent lipid peroxides in cells and is…”
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The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress by Hassan, Syed Shams Ul, Samanta, Saptadip, Dash, Raju, Karpiński, Tomasz M, Habibi, Emran, Sadiq, Abdul, Ahmadi, Amirhossin, Bunagu, Simona

“…Oxidative stress (OS) disrupts the chemical integrity of macromolecules and increases the risk of neurodegenerative diseases. Fisetin is a flavonoid that…”
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Natural Products for Chronic Diseases: A Ray of Hope by Hassan, Syed Shams ul, Abdel-Daim, Mohamed M, Behl, Tapan, Bungau, Simona

“…This Special Issue includes many high advanced quality papers that focus on natural products with their potent pharmacological potential targeting various…”
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An Extensive Pharmacological Evaluation of New Anti-Cancer Triterpenoid (Nummularic Acid) from Ipomoea batatas through In Vitro, In Silico, and In Vivo Studies by Majid, Muhammad, Farhan, Anam, Asad, Muhammad Imran, Khan, Muhammad Rashid, Hassan, Syed Shams Ul, Haq, Ihsan-Ul, Bungau, Simona

“…Prostate cancer (PCa) is the most common cancer in men, accounting for approximately 10% of all new cases in the United States. Plant-derived bioactive…”
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Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic Acids through In Vitro, In Silico and In Vivo Studies by Mahmood, Fawad, Khan, Jamshaid Ali, Mahnashi, Mater H., Jan, Muhammad Saeed, Javed, Muhammad Aamir, Rashid, Umer, Sadiq, Abdul, Hassan, Syed Shams ul, Bungau, Simona

“…In the current study, a series of new (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals (FM1-6) with their corresponding carboxylic acid…”
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Alzheimer’s Disease as a Major Public Health Concern: Role of Dietary Saponins in Mitigating Neurodegenerative Disorders and Their Underlying Mechanisms by Abduljawad, Asaad A, Elawad, Mohammed Ahmed, Elkhalifa, Modawy Elnour Modawy, Ahmed, Alshebli, Hamdoon, Alashary Adam Eisa, Salim, Liga Hasan Mohammed, Ashraf, Muhammad, Ayaz, Muhammad, Hassan, Syed Shams ul, Bungau, Simona

“…Saponins are triterpenoid or steroidal glycosides and are an important group of naturally occurring compounds of plant origin. They exhibit diverse…”
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Potential innovation against Alzheimer’s disorder: a tricomponent combination of natural antioxidants (vitamin E, quercetin, and basil oil) and the development of its intranasal delivery by Karthika, Chenmala, Appu, Anoop Pattanoor, Akter, Rokeya, Rahman, Md. Habibur, Tagde, Priti, Ashraf, Ghulam Md, Abdel-Daim, Mohamed M., Hassan, Syed Shams ul, Abid, Areha, Bungau, Simona

“…Alzheimer’s disorder (AD) is very difficult to manage and treat. The complexity of the brain, the blood–brain barrier influencing a multitude of…”
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Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway by Badshah, Ismail, Qazi, Neelum Gul, Ali, Fawad, Minhas, Amber Mahmood, Alvi, Arooj Mohsin, Kandeel, Mahmoud, Imran, Muhammad, Hassan, Syed Shams Ul, Bungau, Simona

“…Neuropathic pain has been characterized as chronic pain resulting from pathological damage to the sensorimotor system. Because of its complex nature, it…”
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Marine Sponges as a Drug Treasure by Anjum, Komal, Abbas, Syed Qamar, Shah, Sayed Asmat Ali, Akhter, Najeeb, Batool, Sundas, Hassan, Syed Shams Ul

“…Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have…”
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Novel Isoxazole Derivative Attenuates Ethanol-Induced Gastric Mucosal Injury through Inhibition of H+/K+-ATPase Pump, Oxidative Stress and Inflammatory Pathways by Razzaq, Sidra, Minhas, Amber Mahmood, Qazi, Neelum Gul, Nadeem, Humaira, Khan, Arif-ullah, Ali, Fawad, Hassan, Syed Shams ul, Bungau, Simona

“…Isoxazole derivatives are significant enough due to their wide range of pharmacological and therapeutic activities. The purpose of the current study is to use…”
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Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives by Akter, Rokeya, Najda, Agnieszka, Rahman, Md Habibur, Shah, Muddaser, Wesołowska, Sylwia, Hassan, Syed Shams Ul, Mubin, Sidra, Bibi, Parveen, Saeeda, Saeeda

“…Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy (RT) are the common cancer treatments. In addition to these…”
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Pharmacological Basis of Rumex hastatus D. Don in Gastrointestinal Diseases with Focusing Effects on H + /K + -ATPase, Calcium Channels Inhibition and PDE Mediated Signaling: Toxicological Evaluation on Vital Organs by Qazi, Neelum Gul, Khan, Arif-Ullah, Abbasi, Sumra Wajid, Shah, Fawad Ali, Rasheed, Faisal, Ali, Fawad, Hassan, Syed Shams Ul, Bungau, Simona

“…This present study aimed to delineate D. Don crude extract (Rh.Cr), n-Hexane, ethyl acetate, aqueous fractions (Rh.n-Hex, Rh.ETAC, Rh.Aq) and rutin for…”
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In Silico Strategies for Designing of Peptide Inhibitors of Oncogenic K-Ras G12V Mutant: Inhibiting Cancer Growth and Proliferation by Ghufran, Mehreen, Khan, Haider Ali, Ullah, Mehran, Ghufran, Sabreen, Ayaz, Muhammad, Siddiq, Muhammad, Hassan, Syed Shams Ul, Bungau, Simona

“…Ras plays a pivotal function in cell proliferation and is an important protein in signal transduction pathways. Mutations in genes encoding the Ras protein…”
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