Search Results - "Hassan, Sidra"
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An Assessment of Siderophore Production, Mucoviscosity, and Mouse Infection Models for Defining the Virulence Spectrum of Hypervirulent Klebsiella pneumoniae
Published in mSphere (24-03-2021)“…Hypervirulent (hvKp) bacteria are more virulent than classical (cKp) with resultant differences in clinical manifestations and management. It is unclear…”
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Molecular and biological characterization of a novel partitivirus from Talaromyces pinophilus
Published in Virus research (01-05-2024)“…•Mycovirus infection was for the first time shown in Talaromyces pinophilus.•The mycovirus was tentatively named Talaromyces pinophilus partitivirus 1…”
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Facile synthesis, crystal structure, biological evaluation, and molecular modeling studies of N-((4-acetyl phenyl) carbamothioyl) pivalamide as the multitarget-directed ligand
Published in Frontiers in chemistry (26-09-2022)“…The crystal structure of N -((4-acetylphenyl)carbamothioyl)pivalamide (3) was synthesized by inert refluxing pivaloyl isothiocyanate (2) and…”
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Synthesis of novel (E)-1-(2-(2-(4(dimethylamino) benzylidene) hydrazinyl)-4-methylthiazol-5-yl)ethanone derivatives as ecto-5′-nucleotidase inhibitors
Published in Royal Society open science (01-09-2018)“…Ecto-5′-nucleotidase (e5′NT), a membrane-bound enzyme and an essential member of ecto-nucleotidases which regulates extracellular purinergic signalling. Their…”
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5
Vinyl Azides as Radical Acceptors in the Vitamin B 12 -Catalyzed Synthesis of Unsymmetrical Ketones
Published in Organic letters (03-12-2021)“…Vinyl azides are very reactive species and as such are useful building blocks, in particular, in the synthesis of N-heterocycles. They can also serve as…”
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Multicomponent Syntheses based upon Copper-Catalyzed Alkyne-Azide Cycloaddition
Published in Advanced synthesis & catalysis (09-03-2015)“…The copper‐catalyzed alkyne‐azide cycloaddition (CuAAC) is a highly versatile, regioselective synthesis of 1,4‐disubstituted 1,2,3‐triazoles under mild…”
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Vinyl Azides as Radical Acceptors in the Vitamin B12-Catalyzed Synthesis of Unsymmetrical Ketones
Published in Organic letters (03-12-2021)“…Vinyl azides are very reactive species and as such are useful building blocks, in particular, in the synthesis of N-heterocycles. They can also serve as…”
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Synthetic Approaches toward Vitamin B 12 Conjugates
Published in Asian journal of organic chemistry (01-01-2019)“…Abstract The ability to conjugate functional molecules to vitamin B 12 (cobalamin) is an important strategy for the construction of hybrid molecules with…”
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Novel case of empyema necessitans caused by Mycobacterium xenopi
Published in BMJ case reports (12-05-2022)“…Poorly controlled long-standing empyema can dissect through soft tissues and skin resulting in empyema necessitans. We present the first reported case of…”
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Polymeric Nanogel for Oral Delivery of the Chemotherapeutic Agent: Fabrication and Evaluation Alongside Toxicological Studies and Histopathological Examination
Published in AAPS PharmSciTech (26-01-2023)“…Nanogel has attracted considerable attention as one of the most versatile drug delivery systems, especially for site-specific and/or time-controlled delivery…”
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11
A domino reaction of 3-chlorochromones with aminoheterocycles. Synthesis of pyrazolopyridines and benzofuropyridines and their optical and ecto-5'-nucleotidase inhibitory effects
Published in Organic & biomolecular chemistry (2018)“…A new and efficient domino reaction of 3-chlorochromones with electron-rich aminoheterocycles was developed which allows for a convenient synthesis of a…”
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Molecular and biological characterization of a partitivirus from Paecilomyces variotii
Published in Journal of general virology (01-11-2023)“…is a thermo-tolerant, ubiquitous fungus commonly found in food products, indoor environments, soil and clinical samples. It is a well-known biocontrol agent…”
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The effect of albumin in photostabilization of riboflavin: A kinetic study
Published in Journal of photochemistry and photobiology. A, Chemistry. (01-05-2020)“…The chemical interaction of riboflavin (RF) with bovine serum albumin (BSA) results in the formation of a non–fluorescent complex between the two in the ground…”
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14
Synthetic Approaches toward Vitamin B12 Conjugates
Published in Asian journal of organic chemistry (01-01-2019)“…The ability to conjugate functional molecules to vitamin B12 (cobalamin) is an important strategy for the construction of hybrid molecules with various…”
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15
Appraisal of novel azomethine-thioxoimidazolidinone conjugates as ecto-5′-nucleotidase inhibitors: synthesis and molecular docking studies
Published in RSC advances (14-06-2022)“…Purinergic signaling is regulated by a group of extracellular enzymes called ectonucleotidases. One of its members i.e. , ecto-5′-nucleotidase ( h -e5′NT) is…”
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In Silico Prospects and Therapeutic Applications of Ouabagenin and Hydroxylated Corticosteroid Analogues in the Treatment of Lung Cancer
Published in Applied biochemistry and biotechnology (01-12-2022)“…Lung cancer is the second most prevalent carcinoma around the world, and about 80% of patients are of non-small cell lung cancer (NS-CLC). Epidermal growth…”
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Phytocosmeceutical formulation development, characterization and its in-vivo investigations
Published in Biomedicine & pharmacotherapy (01-11-2018)“…The w/o emulsion loaded with 2% Prosopis cineraria extract rich in polyphenol, flavonoids and antioxidants was prepared. The polyphenols and flavonoids inhibit…”
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Repurposing of Strychnine as the Potential Inhibitors of Aldo–keto Reductase Family 1 Members B1 and B10: Computational Modeling and Pharmacokinetic Analysis
Published in The Protein Journal (01-04-2024)“…AKR1B1 and AKR1B10 are important members of aldo–keto reductase family which plays a significant role in cancer progression by modulating cellular metabolism…”
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Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto‐5′‐nucleotidase
Published in Chemical biology & drug design (01-03-2017)“…A series of isonicotinohydrazide derivatives was synthesized and tested against recombinant human and rat ecto‐5′‐nucleotidases (h‐e5′NT and r‐e5′NT) and…”
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Three-component chemoenzymatic synthesis of amide ligated 1,2,3-triazoles
Published in Tetrahedron letters (28-08-2013)“…CAL-B (Candida antarctica lipase B) immobilized on an acrylic resin (Novozyme® 435) smoothly catalyzes the aminolysis of methyl esters with propargyl amine…”
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