Search Results - "Hassan, Ian F."

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  1. 1
    The effect of zoledronate and pamidronate on the intestinal permeability barrier in vitro and in vivo

    The effect of zoledronate and pamidronate on the intestinal permeability barrier in vitro and in vivo by Green, Jonathan R, Clay, Val, Richardson, Joanne, Hassan, Ian F

    Published in International journal of pharmaceutics (16-07-1997)
    “…The intestinal tolerability profile of the potent bisphosphonate compound zoledronate (CGP 42'446) has been compared with that of pamidronate in 2 preclinical…”
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  2. 2
    The transport of acidic amino acids and their analogues across monolayers of human intestinal absorptive (Caco-2) cells in vitro

    The transport of acidic amino acids and their analogues across monolayers of human intestinal absorptive (Caco-2) cells in vitro by Nicklin, Paul L., Irwin, William J., Hassan, Ian F., Mackay, Martin, Dixon, Henry B.F.

    Published in Biochimica et biophysica acta (09-11-1995)
    “…The X − AG system, a sodium-dependent, acidic amino-acid transport system has been implicated in the transport of l-aspartate and l-glutamate across monolayers…”
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  3. 3
    Development of a minimum-calcium Caco-2 monolayer model: Calcium and magnesium ions retard the transport of pamidronate

    Development of a minimum-calcium Caco-2 monolayer model: Calcium and magnesium ions retard the transport of pamidronate by Nicklin, Paul L., Irwin, William J., Hassan, Ian F., Mackay, Martin

    Published in International journal of pharmaceutics (12-09-1995)
    “…The oral absorption of some drug molecules (e.g., tetracyclines and quinolones) is limited by complexation with di- and trivalent metal cations in the…”
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