Search Results - "Hassan, Haider M."

Disrupting the DREAM transcriptional repressor complex induces apolipoprotein overexpression and systemic amyloidosis in mice by Perampalam, Pirunthan, Hassan, Haider M, Lilly, Grace E, Passos, Daniel T, Torchia, Joseph, Kiser, Patti K, Bozovic, Andrea, Kulasingam, Vathany, Dick, Frederick A

“…DREAM (Dp, Rb-like, E2F, and MuvB) is a transcriptional repressor complex that regulates cell proliferation, and its loss causes neonatal lethality in mice. To…”
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Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex by Hassan, Haider M., Kolendowski, Bart, Isovic, Majdina, Bose, Kerstin, Dranse, Helen J., Sampaio, Arthur V., Underhill, T. Michael, Torchia, Joseph

“…Retinoic acid (RA) plays important roles in development, growth, and homeostasis through regulation of the nuclear receptors for RA (RARs). Herein, we identify…”
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Regulation of Chromatin Accessibility by the Farnesoid X Receptor Is Essential for Circadian and Bile Acid Homeostasis In Vivo by Hassan, Haider M, Onabote, Oladapo, Isovic, Majdina, Passos, Daniel T, Dick, Frederick A, Torchia, Joseph

“…The Farnesoid X Receptor (FXR) belongs to the nuclear receptor superfamily and is an essential bile acid (BA) receptor that regulates the expression of genes…”
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Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma by Hassan, Haider M., Isovic, Majdina, Kolendowski, Bart, Bauer-Maison, Natasha, Onabote, Oladapo, Cecchini, Matthew, Haig, Aaron, Maleki Vareki, Saman, Underhill, T. Michael, Torchia, Joseph

“…Thymine DNA glycosylase (TDG) is a nuclear receptor coactivator that plays an essential role in the maintenance of epigenetic stability in cells. Here, we…”
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TDG is a novel tumor suppressor of liver malignancies by Hassan, Haider M., Isovic, Majdina, Underhill, Michael Tully, Torchia, Joseph

“…In a recent publication, we demonstrated that conditional deletion of the gene encoding thymine DNA glycosylase (TDG) leads to a late onset of hepatocellular…”
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The Role of Thymine DNA Glycosylase in Transcription, Active DNA Demethylation, and Cancer by Onabote, Oladapo, Hassan, Haider M, Isovic, Majdina, Torchia, Joseph

“…DNA methylation is an essential covalent modification that is required for growth and development. Once considered to be a relatively stable epigenetic mark,…”
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TBX3 promotes progression of pre‐invasive breast cancer cells by inducing EMT and directly up‐regulating SLUG by Krstic, Milica, Kolendowski, Bart, Cecchini, Matthew J, Postenka, Carl O, Hassan, Haider M, Andrews, Joseph, MacMillan, Connor D, Williams, Karla C, Leong, Hon S, Brackstone, Muriel, Torchia, Joseph, Chambers, Ann F, Tuck, Alan B

“…The acquisition of cellular invasiveness by breast epithelial cells and subsequent transition from ductal carcinoma in situ (DCIS) to invasive breast cancer is…”
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Mapping Retinoic Acid-Dependant 5mC Derivatives in Mouse Embryonic Fibroblasts by Hassan, Haider M, Underhill, T Michael, Torchia, Joseph

“…Methylase-assisted bisulfite sequencing (MAB-seq) is a derivatization technique to evaluate the presence of 5-formylcytosine (5-fC) and 5-carboxylcytosine…”
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Isoform-specific promotion of breast cancer tumorigenicity by TBX3 involves induction of angiogenesis by Krstic, Milica, Hassan, Haider M., Kolendowski, Bart, Hague, M. Nicole, Anborgh, Pieter. H., Postenka, Carl O., Torchia, Joseph, Chambers, Ann F., Tuck, Alan B.

“…TBX3 is a member of the highly conserved family of T-box transcription factors involved in embryogenesis, organogenesis and tumor progression. While the…”
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Synthesis, Characterization, in silico DFT, Molecular docking, ADMET Profiling Studies and Toxicity Predictions of Ag(I) Complex Derived from 4‐Aminoacetophenone by Kyhoiesh, Hussein Ali Kadhim, Hassan, Haider M.

“…The reaction of the synthesized (E)‐1‐(4‐((2,4‐dihydroxy‐6‐methylphenyl)diazenyl)phenyl)ethan‐1‐one, (DMPDE) ligand with Ag(I) ion at room temperature resulted…”
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Synthesis, characterization, biological applications, and molecular docking studies of some transition metal complexes with azo dye ligand derived from 5-methyl imidazole by Al-Adilee, Khalid J., Jawad, Sajjad H., Kyhoiesh, Hussein Ali Kadhim, Hassan, Haider M.

“…•Various methods were used to synthesize and characterize new free ligand and metal complexes.•Molecular docking was used to demonstrate the activity of…”
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Antibacterial activity of northern Ontario medicinal plant extracts by Hassan, Haider M., Jiang, Zi-Hua, Asmussen, Christina, McDonald, Emma, Qin, Wensheng

“…Hassan, H. M., Jiang, Z.-H., Asmussen, C., McDonald, E. and Qin, W. 2014. Antibacterial activity of northern Ontario medicinal plant extracts. Can. J. Plant…”
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Review: Northern Ontario medicinal plants by Hassan, Haider M., Jiang, Zi-Hua, Syed, Tarannum A., Qin, Wensheng

“…Hassan, H. M., Jiang, Z.-H., Syed, T. A. and Qin, W. 2012. Review: Northern Ontario medicinal plants. Can. J. Plant Sci. 92: 815–828. The majority of scholarly…”
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Antibacterial activity of northern Ontario medicinal plant extracts by Hassan, Haider M, Jiang, Zi-Hua, Asmussen, Christina, McDonald, Emma, Qin, Wensheng

“…Hassan, H. M., Jiang, Z.-H., Asmussen, C., McDonald, E. and Qin, W. 2014. Antibacterial activity of northern Ontario medicinal plant extracts. Can. J. Plant…”
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Review: Northern Ontario medicinal plants by Hassan, Haider M, Jiang, Zi-Hua, Syed, Tarannum A, Qin, Wensheng

“…Hassan, H. M., Jiang, Z.-H., Syed, T. A. and Qin, W. 2012. Review: Northern Ontario medicinal plants. Can. J. Plant Sci. 92: 815-828. The majority of scholarly…”
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Effect of feeding pattern on the stage of primary dentition eruption in relation to growth parameters by Hassan, Dhay HM, Al-joranii, Shahbaa M, Yas, Baydaa A, Razeghi, Samaneh

“…Background: Feeding is a complicated process that involves the coordination of cardiovascular, respiratory, gastrointestinal (GI), and oropharyngeal…”
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