Search Results - "Hassall, Cedric H."

Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid by Atherton, Frank R, Hassall, Cedric H, Lambert, Robert W

“…Phosphonodipeptides and phosphonooligopeptides based on L- and D-(1-aminoethyl)phosphonic acids L-Ala(P) and D-Ala(P) and (aminomethyl)phosphonic acid Gly(P)…”
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Phosphonopeptides as Antibacterial Agents: Mechanism of Action of Alaphosphin by Atherton, F R, Hall, M J, Hassall, C H, Lambert, R W, Lloyd, W J, Ringrose, P S

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Phosphonopeptides as Antibacterial Agents: Rationale, Chemistry, and Structure-Activity Relationships by Atherton, F R, Hall, M J, Hassall, C H, Lambert, R W, Ringrose, P S

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Phosphonopeptides as Antibacterial Agents: Alaphosphin and Related Phosphonopeptides by Allen, J G, Atherton, F R, Hall, M J, Hassall, C H, Holmes, S W, Lambert, R W, Nisbet, L J, Ringrose, P S

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Synthesis and antitumor activity of 9-[(carbamoyloxy)alkyl]anthracyclines a novel class of anthracycline derivatives by Adams, Nigel, Blake, Colin, Broadhurst, Michael J, Bushnell, David J, Hassall, Cedric H, Hartmann, Hans R, Keech, Elizabeth, Stratton, Alan R, Thomas, Gareth J

“…A number of 4-demethoxyanthracyclines having hydroxylalkyl functions at the 9-position have previously been synthesized and shown to have potent antitumor…”
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Synthesis and antitumor activity of novel 4-demethoxyanthracyclines by Adams, Nigel, Blake, Colin, Broadhurst, Michael J, Bushnell, David J, Hassall, Cedric H, Hartmann, Hans R, Keech, Elizabeth, Stratton, Alan R, Thomas, Gareth J

“…A versatile and efficient synthetic route to 4-demethoxyanthracyclinones has been utilized in the preparation of a number of aglycons having 9-alkyl,…”
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The Synthesis of (3S,5S)-5-Hydroxyhexahydropyridazine-3-carboxylic Acid by H. Hassall, Cedric, L. Ramachandran, Kuzhalmannam

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Amino-acids and peptides Part XVI. Synthesis of cyclo-[L-(alpha-amino)-beta-alanylglycyl-D-(alpha-amino)-beta-alanylglycyl] and related fourteen-membered cyclotetrapeptides by Hassall, C H, Tyson, R G, Chexal, K K

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The structure of ekatetrone, a metabolite of strains of Streptomyces aureofaciens by Prikrylová, V, Podojil, M, Sedmera, P, Vokoun, J, Vanĕk, Z

“…The structure of ekatetrone has been determined from physico-chemical data obtained using the natural compound, its derivatives and products of degradation…”
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Amino-acids and peptides. Part XVIII. Studies relating to the synthesis and conformation of a novel bicyclic peptide system by Chexal, K K, Handa, B K, Hassall, C H, Thomas, W A

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New potent inhibitors of angiotensin converting enzyme by Attwood, Michael R., Francis, R.John, Hassall, Cedric H., Kröhn, Antonin, Lawton, Geoffrey, Natoff, Ian L., Nixon, John S., Redshaw, Sally, Thomas, W.Anthony

“…Using an earlier model of the favoured orientation of binding functions of angiotensin converting enzyme (ACE) inhibitors, it has been possible to postulate a…”
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Dihomo‐γ‐linolenic acid reverses hypertension induced in rats by diets rich in saturated fat by Hassall, Cedric H., Kirtland, Stephen J.

“…This study has shown that hypertension induced in rats by a diet rich in saturated fat (16% coconut oil, 4% palmitic acid by weight) is reversed by the…”
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A new class of inhibitors of human leucocyte elastase by Hassall, Cedric H., Johnson, William H., Kennedy, Anthony J., Roberts, Noel A.

“…Studies of the inhibition of elastases at a molecular level have resulted in the identification of protected dipeptides which are reversible and highly…”
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The design of a new group of angiotensin-converting enzyme inhibitors by Hassall, Cedric H., Kröhn, Antonin, Moody, Christopher J., Anthony Thomas, W.

“…Using X-ray and NMR data relating to the conformation of the antihypertensive, angiotensin-converting enzyme inhibitor, captopril, and structure—activity…”
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