Search Results - "Hasley, Rebecca"
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Application of the Caprini Risk Assessment Model to Select Patients for Extended Thromboembolism Prophylaxis After Sleeve Gastrectomy
Published in Journal of gastrointestinal surgery (01-02-2022)“…Background The Caprini risk assessment model is a well-validated tool that identifies patients who would benefit from extended venous thromboembolism (VTE)…”
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Activated platelet–T-cell conjugates in peripheral blood of patients with HIV infection: coupling coagulation/inflammation and T cells
Published in AIDS (London) (17-07-2015)“…BACKGROUND:Despite successfully suppressed viremia by treatment, patients with high levels of biomarkers of coagulation/inflammation are at an increased risk…”
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Perioperative Outcomes for Centers Routinely Admitting Postoperative Endovascular Aortic Aneurysm Repair to the ICU
Published in Journal of the American College of Surgeons (01-06-2021)“…Intensive care unit (ICU) admission after endovascular aortic aneurysm repair (EVAR) varies across medical centers. We evaluated the association of…”
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Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis
Published in PLoS pathogens (01-03-2014)“…HIV infection and the associated chronic immune activation alter T cell homeostasis leading to CD4 T cell depletion and CD8 T cell expansion. The mechanisms…”
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Enhanced Effector Function of CD8+T Cells From Healthy Controls and HIV-Infected Patients Occurs Through Thrombin Activation of Protease-Activated Receptor 1
Published in The Journal of infectious diseases (15-02-2013)“…Disruption of vascular integrity by trauma and other tissue insults leads to inflammation and activation of the coagulation cascade. The serine protease…”
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Reasons for long-term tunneled dialysis catheter use and associated morbidity
Published in Journal of vascular surgery (01-02-2021)“…Tunneled dialysis catheters (TDCs) are generally used as a temporary means to provide hemodialysis until permanent arteriovenous (AV) access is established…”
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The role of protease-activated receptor 1 signaling in CD8 T cell effector functions
Published in iScience (19-11-2021)“…CD8 T cells are essential for adaptive immunity against viral infections. Protease activated receptor 1 (PAR1) is expressed by CD8 T cells; however, its role…”
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The CD8+HLA‐DR+ T cells expanded in HIV‐1 infection are qualitatively identical to those from healthy controls
Published in European journal of immunology (01-10-2012)“…HIV‐induced immune activation leads to expansion of a subset of human CD8+ T cells expressing HLA‐DR antigens. Expansion of CD8+HLA‐DR+ T cells can be also…”
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HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127
Published in AIDS (London) (31-07-2013)“…During HIV infection distinct mechanisms drive immune activation of the CD4 and CD8 T cells leading to CD4 T-cell depletion and expansion of the CD8 T-cell…”
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IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion
Published in JCI insight (16-11-2017)“…IL-7 regulates homeostatic mechanisms that maintain the overall size of the T cell pool throughout life. We show that, under steady-state conditions, IL-7…”
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158 : Lymphopenia modulates levels of signal transducer and activator of transcription-1 expression leading to enhanced CD4 T cell responsiveness to type-I IFN
Published in Cytokine (Philadelphia, Pa.) (01-09-2013)“…To maintain the size of T cell pools throughout life, homeostatic mechanisms regulate both survival and proliferation, which is achieved by IL-7 and TCR…”
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Quantitative sensory testing measures individual pain responses in emergency department patients
Published in Journal of pain research (01-01-2017)“…Refining and individualizing treatment of acute pain in the emergency department (ED) is a high priority, given that painful complaints are the most common…”
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Surgical Episodes of Care for Price Transparency using the Episode Grouper for Medicare
Published in Annals of surgery (01-12-2023)“…This proof-of-concept explores the use of an episode grouper to more accurately identify the complete set of surgical services typically provided in a surgical…”
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PAR1 signaling is involved in TCR-mediated CD8 T cell granule exocytosis
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract The Protease Activated Receptor (PAR1) is the receptor of thrombin, the main serine protease of the coagulation cascade. PAR1 is expressed by…”
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Long-term Tunneled Dialysis Catheter Use Is Not Associated With Mortality but Is Associated With Increased Morbidity
Published in Journal of vascular surgery (01-09-2020)Get full text
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Title: Frontal-pole Neuromodulation for Impulsivity and Suicidality in Veterans with Mild Traumatic Brain Injury and Common Co-Occurring Mental Health Conditions: Protocol for a Pilot Randomized Controlled Trial (Preprint)
Published in JMIR research protocols (09-03-2024)Get full text
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Overexpression of total STAT1 during lymphopenia-induced proliferation leads to decrease CD4 T cell survival
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract To preserve the size and diversity of the T cell repertoire throughout life, homeostatic mechanisms regulate both survival and proliferation through…”
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IL-7-dependent STAT1 activation limits homeostatic CD4 T cell expansion
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract IL-7 regulates homeostatic mechanisms that maintain the overall size of the T cell pool throughout life. We show that under steady state conditions,…”
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Role of IFN-α signaling in T cell pool dysregulation during chronic exposure to type-I IFN under lymphopenic conditions: impact on HIV pathogenesis (VIR9P.1145)
Published in The Journal of immunology (1950) (01-05-2015)“…Abstract HIV infection and its associated chronic immune activation alter T cell homeostasis leading to CD4 T cell depletion and CD8 T cell expansion. The…”
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Increased activated platelet-T cell conjugates in patients with HIV infection: relationship between coagulation/inflammation and T cells. (VIR10P.1171)
Published in The Journal of immunology (1950) (01-05-2015)“…Abstract While antiretroviral therapies can successfully suppress HIV replication, there remains evidence of persistent immune activation, which is correlated…”
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