Search Results - "Hasler, Pascal W."

Validation of automated artificial intelligence segmentation of optical coherence tomography images by Maloca, Peter M, Lee, Aaron Y, de Carvalho, Emanuel R, Okada, Mali, Fasler, Katrin, Leung, Irene, Hörmann, Beat, Kaiser, Pascal, Suter, Susanne, Hasler, Pascal W, Zarranz-Ventura, Javier, Egan, Catherine, Heeren, Tjebo F C, Balaskas, Konstantinos, Tufail, Adnan, Scholl, Hendrik P N

“…To benchmark the human and machine performance of spectral-domain (SD) and swept-source (SS) optical coherence tomography (OCT) image segmentation, i.e.,…”
Get full text

Central serous chorioretinopathy by Wang, Maria, Munch, Inger Christine, Hasler, Pascal W., Prünte, Christian, Larsen, Michael

“… Central serous chorioretinopathy (CSC) is a disease of the retina characterized by serous detachment of the neurosensory retina secondary to one or more…”
Get full text

Volumetric subfield analysis of cynomolgus monkey’s choroid derived from hybrid machine learning optical coherence tomography segmentation by Maloca, Peter M, Valmaggia, Philippe, Hartmann, Theresa, Juedes, Marlene, Hasler, Pascal W, Scholl, Hendrik P. N, Denk, Nora

“…This study aimed to provide volumetric choroidal readings regarding sex, origin, and eye side from healthy cynomolgus monkey eyes as a reference database using…”
Get full text

Macular thickness measurements of healthy, naïve cynomolgus monkeys assessed with spectral-domain optical coherence tomography (SD-OCT) by Denk, Nora, Maloca, Peter, Steiner, Guido, Freichel, Christian, Bassett, Simon, Schnitzer, Tobias K, Hasler, Pascal W

“…The purpose of this study was to measure central macular thickness in an unprecedented number of cynomolgus monkeys. Macular thickness was measured with…”
Get full text

A 3D model to evaluate retinal nerve fiber layer thickness deviations caused by the displacement of optical coherence tomography circular scans in cynomolgus monkeys (Macaca fascicularis) by Niklaus, Stephanie, Hasler, Pascal W, Bryant, Timothy, Desgent, Sebastien, Vezina, Mark, Schnitzer, Tobias K, Maloca, Peter M, Denk, Nora

“…The main objective of the study was to analyze deviations in retinal nerve fiber layer (RNFL) thickness measurements caused by the displacement of circular…”
Get full text

Autologous internal limiting membrane transplantation achieves anatomic closure and functional improvement in the treatment of large, persistent macular holes by Camenzind-Zuche, Hanna, Janeschitz-Kriegl, Lucas, Hasler, Pascal W, Prünte, Christian

“…To evaluate the clinical outcome of subretinal autologous internal limiting membrane (ILM) transplantation during pars-plana vitrectomy for persistent…”
Get full text

Uncovering of intraspecies macular heterogeneity in cynomolgus monkeys using hybrid machine learning optical coherence tomography image segmentation by Maloca, Peter M., Seeger, Christine, Booler, Helen, Valmaggia, Philippe, Kawamoto, Ken, Kaba, Qayim, Inglin, Nadja, Balaskas, Konstantinos, Egan, Catherine, Tufail, Adnan, Scholl, Hendrik P. N., Hasler, Pascal W., Denk, Nora

“…The fovea is a depression in the center of the macula and is the site of the highest visual acuity. Optical coherence tomography (OCT) has contributed…”
Get full text

Novel biomarker of sphericity and cylindricity indices in volume-rendering optical coherence tomography angiography in normal and diabetic eyes: a preliminary study by Maloca, Peter M., Spaide, Richard F., de Carvalho, Emanuel Ramos, Studer, Harald P., W Hasler, Pascal, Scholl, Hendrik P. N., Heeren, Tjebo F. C., Schottenhamml, Julia, Balaskas, Konstantinos, Tufail, Adnan, Egan, Catherine

“…Purpose Preliminary to evaluate geometric indices (vessel sphericity and cylindricity) for volume-rendered optical coherence tomography angiography (OCTA) in…”
Get full text

Interdevice variability of central corneal thickness measurement by Maloca, Peter M, Studer, Harald P, Ambrósio, Jr, Renato, Goldblum, David, Rothenbuehler, Simon, Barthelmes, Daniel, Zweifel, Sandrine, Scholl, Hendrik P N, Balaskas, Konstantinos, Tufail, Adnan, Hasler, Pascal W

“…To evaluate variability of central corneal thickness measurement (CCT) devices using a hitherto unprecedented number of CCT devices. CCT was measured…”
Get full text

Safety study of 38 503 intravitreal ranibizumab injections performed mainly by physicians in training and nurses in a hospital setting by Hasler, Pascal W., Brandi Bloch, Sara, Villumsen, Jørgen, Fuchs, Josefine, Lund‐Andersen, Henrik, Larsen, Michael

“…Purpose To evaluate and to compare the safety of intravitreal ranibizumab injections performed by physicians and nurses at a single large hospital clinic in…”
Get full text

Real-world outcomes of micropulse transscleral laser therapy in glaucoma patients: Efficacy of initial and repeated treatment, transient intraocular pressure spikes by Dervos, Thomas, Fortuna, Laura L., Gugleta, Konstantin, Scholl, Hendrik P.N., Gatzioufas, Zisis, Hasler, Pascal W., Arabin, Valentin, Enz, Tim J.

“…To investigate the clinical outcomes of micropulse transscleral laser therapy (MP-TLT) in a cohort of glaucoma patients, including safety profile,…”
Get full text

Enhanced resolution and speckle‐free three‐dimensional printing of macular optical coherence tomography angiography by Maloca, Peter M., Spaide, Richard F., Rothenbuehler, Simon, Scholl, Hendrik P. N., Heeren, Tjebo, Ramos de Carvalho, João E., Okada, Mali, Hasler, Pascal W., Egan, Catherine, Tufail, Adnan

Get full text

Unraveling the deep learning gearbox in optical coherence tomography image segmentation towards explainable artificial intelligence by Maloca, Peter M., Müller, Philipp L., Lee, Aaron Y., Tufail, Adnan, Balaskas, Konstantinos, Niklaus, Stephanie, Kaiser, Pascal, Suter, Susanne, Zarranz-Ventura, Javier, Egan, Catherine, Scholl, Hendrik P. N., Schnitzer, Tobias K., Singer, Thomas, Hasler, Pascal W., Denk, Nora

“…Machine learning has greatly facilitated the analysis of medical data, while the internal operations usually remain intransparent. To better comprehend these…”
Get full text

Correlation between intraretinal changes in diabetic macular oedema seen in fluorescein angiography and optical coherence tomography by Soliman, Wael, Sander, Birgit, Hasler, Pascal W., Larsen, Michael

“… Purpose:  To study the relationship between intraretinal optical coherence tomography (OCT) and fluorescein angiography (FA) findings in eyes with diabetic…”
Get full text

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution by Cowan, Cameron S., Renner, Magdalena, De Gennaro, Martina, Gross-Scherf, Brigitte, Goldblum, David, Hou, Yanyan, Munz, Martin, Rodrigues, Tiago M., Krol, Jacek, Szikra, Tamas, Cuttat, Rachel, Waldt, Annick, Papasaikas, Panagiotis, Diggelmann, Roland, Patino-Alvarez, Claudia P., Galliker, Patricia, Spirig, Stefan E., Pavlinic, Dinko, Gerber-Hollbach, Nadine, Schuierer, Sven, Srdanovic, Aldin, Balogh, Marton, Panero, Riccardo, Kusnyerik, Akos, Szabo, Arnold, Stadler, Michael B., Orgül, Selim, Picelli, Simone, Hasler, Pascal W., Hierlemann, Andreas, Scholl, Hendrik P.N., Roma, Guglielmo, Nigsch, Florian, Roska, Botond

“…Human organoids recapitulating the cell-type diversity and function of their target organ are valuable for basic and translational research. We developed…”
Get full text

Primary Open-Angle Glaucoma Progression in Glaucoma Patients with Unchanged Topical Treatment over 3 Years - Retrospective Observational Cohort Analysis by Saruhan, Yasemin, Hasler, Pascal W, Gugleta, Konstantin

“…Lowering intraocular pressure (IOP) is a mainstay of glaucoma therapy. It is, however, still an open question whether a comparable level of long-term IOP…”
Get more information

En Face Optical Coherence Tomography Imaging Ellipsoid Zone Regeneration in Laser-Induced and Solar Maculopathies by Zweifel, Sandrine A., Hasler, Pascal W., Maloca, Peter, Barthelmes, Daniel, Fasler, Katrin, Gunzinger, Jeanne M., Böni, Christian

“…The purpose of the study was to analyze imaging findings in spectral domain en face optical coherence tomography (SD OCT) in patients with laser‐induced and…”
Get full text

Vasoactive peptides as biomarkers for the prediction of retinopathy of prematurity by Neumann, Roland P., Gerull, Roland, Hasler, Pascal W., Wellmann, Sven, Schulzke, Sven M.

“…Background Retinopathy of prematurity (ROP) is a major complication in preterm infants. We assessed if plasma levels of midregional pro-atrial natriuretic…”
Get full text

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans by Jüttner, Josephine, Szabo, Arnold, Gross-Scherf, Brigitte, Morikawa, Rei K., Rompani, Santiago B., Hantz, Peter, Szikra, Tamas, Esposti, Federico, Cowan, Cameron S., Bharioke, Arjun, Patino-Alvarez, Claudia P., Keles, Özkan, Kusnyerik, Akos, Azoulay, Thierry, Hartl, Dominik, Krebs, Arnaud R., Schübeler, Dirk, Hajdu, Rozina I., Lukats, Akos, Nemeth, Janos, Nagy, Zoltan Z., Wu, Kun-Chao, Wu, Rong-Han, Xiang, Lue, Fang, Xiao-Long, Jin, Zi-Bing, Goldblum, David, Hasler, Pascal W., Scholl, Hendrik P. N., Krol, Jacek, Roska, Botond

“…Targeting genes to specific neuronal or glial cell types is valuable for both understanding and repairing brain circuits. Adeno-associated viruses (AAVs) are…”
Get full text

A pilot study to image the vascular network of small melanocytic choroidal tumors with speckle noise-free 1050-nm swept source optical coherence tomography (OCT choroidal angiography) by Maloca, Peter, Gyger, Cyrill, Hasler, Pascal W.

“…Purpose To visualize and measure the vascular network of melanocytic choroidal tumors with speckle noise-free swept source optical coherence tomography (SS-OCT…”
Get full text