Search Results - "Haskins, Ryan M"
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KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
Published in Nature medicine (01-06-2015)“…A high percentage of smooth muscle cells in atherosclerotic lesions lose expression of smooth muscle marker proteins and acquire the phenotype of other cell…”
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KLF4 (Kruppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue inflammation
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2021)“…OBJECTIVE:Smooth muscle cells and pericytes display remarkable plasticity during injury and disease progression. Here, we tested the hypothesis that…”
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The fate of an inhaled cigarette puff in the human respiratory tract
Published in Inhalation toxicology (02-07-2024)“…Cigarette smoking can lead to a host of adverse health effects such as lung and heart disease. Increased lung cancer risk is associated with inhalation of…”
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Small molecule inhibition of non-canonical (TAK1-mediated) BMP signaling results in reduced chondrogenic ossification and heterotopic ossification in a rat model of blast-associated combat-related lower limb trauma
Published in Bone (New York, N.Y.) (01-10-2020)“…Heterotopic ossification (HO) is defined as ectopic bone formation around joints and in soft tissues following trauma, particularly blast-related extremity…”
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Novel Autoimmune IgM Antibody Attenuates Atherosclerosis in IgM Deficient Low-Fat Diet–Fed, but Not Western Diet–Fed Apoe–/– Mice
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2020)“…OBJECTIVE:Oxidized phospholipids (OxPL), such as the oxidized derivatives of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine,…”
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BMP Ligand Trap ALK3-Fc Attenuates Osteogenesis and Heterotopic Ossification in Blast-Related Lower Extremity Trauma
Published in Stem cells and development (15-01-2021)“…Traumatic heterotopic ossification (tHO) commonly develops in wounded service members who sustain high-energy and blast-related traumatic amputations…”
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Klf4 has an unexpected protective role in perivascular cells within the microvasculature
Published in American journal of physiology. Heart and circulatory physiology (01-08-2018)“…Recent smooth muscle cell (SMC) lineage-tracing studies have revealed that SMCs undergo remarkable changes in phenotype during development of atherosclerosis…”
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Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
Published in Nature medicine (01-02-2016)Get full text
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Erratum: Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
Published in Nature medicine (04-02-2016)Get full text
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Correction: Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
Published in Nature medicine (2016)“…Nat. Med. 21, 628–637 (2015); published online 18 May 2015; corrected after print 12 August 2015 In the version of this article initially published, the labels…”
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KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role in Atherosclerotic Plaque Pathogenesis
Published in Nature medicine (18-05-2015)“…Herein we employ Myh11 -CreER T2 ROSA floxed STOP eYFP Apoe −/− smooth muscle cell (SMC) lineage tracing mice to show that traditional methods for detecting…”
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