Search Results - "Haskins, Ryan"

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis by Shankman, Laura S, Gomez, Delphine, Cherepanova, Olga A, Salmon, Morgan, Alencar, Gabriel F, Haskins, Ryan M, Swiatlowska, Pamela, Newman, Alexandra A C, Greene, Elizabeth S, Straub, Adam C, Isakson, Brant, Randolph, Gwendalyn J, Owens, Gary K

“…A high percentage of smooth muscle cells in atherosclerotic lesions lose expression of smooth muscle marker proteins and acquire the phenotype of other cell…”
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The fate of an inhaled cigarette puff in the human respiratory tract by Asgharian, Bahman, Price, Owen, Wasdo, Scott, Li, Cissy, Peters, Kamau O, Haskins, Ryan M, Chemerynski, Susan, Schroeter, Jeffry

“…Cigarette smoking can lead to a host of adverse health effects such as lung and heart disease. Increased lung cancer risk is associated with inhalation of…”
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KLF4 (Kruppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue inflammation by Bulut, Gamze B., Alencar, Gabriel F., Owsiany, Katherine M., Nguyen, Anh T., Karnewar, Santosh, Haskins, Ryan M., Waller, Lillian K., Cherepanova, Olga A., Deaton, Rebecca A., Shankman, Laura S., Keller, Susanna R., Owens, Gary K.

“…OBJECTIVE:Smooth muscle cells and pericytes display remarkable plasticity during injury and disease progression. Here, we tested the hypothesis that…”
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Small molecule inhibition of non-canonical (TAK1-mediated) BMP signaling results in reduced chondrogenic ossification and heterotopic ossification in a rat model of blast-associated combat-related lower limb trauma by Strong, Amy L., Spreadborough, Philip J., Pagani, Chase A., Haskins, Ryan M., Dey, Devaveena, Grimm, Patrick D., Kaneko, Keiko, Marini, Simone, Huber, Amanda K., Hwang, Charles, Westover, Kenneth, Mishina, Yuji, Bradley, Matthew J., Levi, Benjamin, Davis, Thomas A.

“…Heterotopic ossification (HO) is defined as ectopic bone formation around joints and in soft tissues following trauma, particularly blast-related extremity…”
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Novel Autoimmune IgM Antibody Attenuates Atherosclerosis in IgM Deficient Low-Fat Diet–Fed, but Not Western Diet–Fed Apoe–/– Mice by Cherepanova, Olga A., Srikakulapu, Prasad, Greene, Elizabeth S., Chaklader, Malay, Haskins, Ryan M., McCanna, Mary E., Bandyopadhyay, Smarajit, Ban, Bhupal, Leitinger, Norbert, McNamara, Coleen A., Owens, Gary K.

“…OBJECTIVE:Oxidized phospholipids (OxPL), such as the oxidized derivatives of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine,…”
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BMP Ligand Trap ALK3-Fc Attenuates Osteogenesis and Heterotopic Ossification in Blast-Related Lower Extremity Trauma by Strong, Amy L, Spreadborough, Philip J, Dey, Devaveena, Yang, Peiran, Li, Shuli, Lee, Arthur, Haskins, Ryan M, Grimm, Patrick D, Kumar, Ravi, Bradley, Matthew J, Yu, Paul B, Levi, Benjamin, Davis, Thomas A

“…Traumatic heterotopic ossification (tHO) commonly develops in wounded service members who sustain high-energy and blast-related traumatic amputations…”
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Klf4 has an unexpected protective role in perivascular cells within the microvasculature by Haskins, Ryan M, Nguyen, Anh T, Alencar, Gabriel F, Billaud, Marie, Kelly-Goss, Molly R, Good, Miranda E, Bottermann, Katharina, Klibanov, Alexander L, French, Brent A, Harris, Thurl E, Peirce, Shayn M, Isakson, Brant E, Owens, Gary K

“…Recent smooth muscle cell (SMC) lineage-tracing studies have revealed that SMCs undergo remarkable changes in phenotype during development of atherosclerosis…”
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Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis by Shankman, Laura S, Gomez, Delphine, Cherepanova, Olga A, Salmon, Morgan, Alencar, Gabriel F, Haskins, Ryan M, Swiatlowska, Pamela, Newman, Alexandra A C, Greene, Elizabeth S, Straub, Adam C, Isakson, Brant, Randolph, Gwendalyn J, Owens, Gary K

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Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis by Alencar, Gabriel F., Owsiany, Katherine M., Karnewar, Santosh, Sukhavasi, Katyayani, Mocci, Giuseppe, Nguyen, Anh T., Williams, Corey M., Shamsuzzaman, Sohel, Mokry, Michal, Henderson, Christopher A., Haskins, Ryan, Baylis, Richard A., Finn, Aloke V., McNamara, Coleen A., Zunder, Eli R., Venkata, Vamsidhar, Pasterkamp, Gerard, Björkegren, Johan, Bekiranov, Stefan, Owens, Gary K.

“…Rupture and erosion of advanced atherosclerotic lesions with a resultant myocardial infarction or stroke are the leading worldwide cause of death. However, we…”
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Abstract 17184: Nearly One Third of GWAS CAD Are Putative SMC Klf4 or Oct4 Targets in Advanced Atherosclerotic Lesions by Alencar, Gabriel F, Haskins, Ryan, Venkata, Vamsidhar M, Bjorkegren, Johan, Bekiranov, Stefan, Owens, Gary K

“…Atherosclerosis is a disease of chronic inflammation and the leading cause of morbidity and mortality worldwide. Despite decades of research, our understanding…”
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Cardiovascular Outcomes among Combustible-Tobacco and Electronic Nicotine Delivery System (ENDS) Users in Waves 1 through 5 of the Population Assessment of Tobacco and Health (PATH) Study, 2013-2019 by Mahoney, Martin C, Rivard, Cheryl, Kimmel, Heather L, Hammad, Hoda T, Sharma, Eva, Halenar, Michael J, Sargent, Jim, Cummings, K Michael, Niaura, Ray, Goniewicz, Maciej L, Bansal-Travers, Maansi, Hatsukami, Dorothy, Gaalema, Diann, Fong, Geoffrey, Gravely, Shannon, Christensen, Carol H, Haskins, Ryan, Silveira, Marushka L, Blanco, Carlos, Compton, Wilson, Stanton, Cassandra A, Hyland, Andrew

“…Prior studies have not clearly established risk of cardiovascular disease (CVD) among smokers who switch to exclusive use of electronic nicotine delivery…”
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Erratum: Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis by Shankman, Laura S, Gomez, Delphine, Cherepanova, Olga A, Salmon, Morgan, Alencar, Gabriel F, Haskins, Ryan M, Swiatlowska, Pamela, Newman, Alexandra A C, Greene, Elizabeth S, Straub, Adam C, Isakson, Brant, Randolph, Gwendalyn J, Owens, Gary K

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Correction: Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis by Shankman, Laura S, Gomez, Delphine, Cherepanova, Olga A, Salmon, Morgan, Alencar, Gabriel F, Haskins, Ryan M, Swiatlowska, Pamela, Newman, Alexandra A C, Greene, Elizabeth S, Straub, Adam C, Isakson, Brant, Randolph, Gwendalyn J, Owens, Gary K

“…Nat. Med. 21, 628–637 (2015); published online 18 May 2015; corrected after print 12 August 2015 In the version of this article initially published, the labels…”
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KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role in Atherosclerotic Plaque Pathogenesis by Shankman, Laura S., Gomez, Delphine, Cherepanova, Olga A., Salmon, Morgan, Alencar, Gabriel F., Haskins, Ryan M., Swiatlowska, Pamela, Newman, Alexandra A. C., Greene, Elizabeth S., Straub, Adam C., Isakson, Brant, Randolph, Gwendalyn J., Owens, Gary K.

“…Herein we employ Myh11 -CreER T2 ROSA floxed STOP eYFP Apoe −/− smooth muscle cell (SMC) lineage tracing mice to show that traditional methods for detecting…”
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