Search Results - "Haskins, Jonathan W."

EGF Receptor Activates MET through MAPK to Enhance Non-Small Cell Lung Carcinoma Invasion and Brain Metastasis by BREINDEL, Jerrica L, HASKINS, Jonathan W, COWELL, Elizabeth P, MINGHUI ZHAO, NGUYEN, Don X, STERN, David F

“…MET amplification as a mechanism of acquired resistance to EGF receptor (EGFR)-targeted therapies in non-small cell lung carcinoma (NSCLC) led to investigation…”
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Genotype-selective combination therapies for melanoma identified by high-throughput drug screening by Held, Matthew A, Langdon, Casey G, Platt, James T, Graham-Steed, Tisheeka, Liu, Zongzhi, Chakraborty, Ashok, Bacchiocchi, Antonella, Koo, Andrew, Haskins, Jonathan W, Bosenberg, Marcus W, Stern, David F

“…Resistance and partial responses to targeted monotherapy are major obstacles in cancer treatment. Systematic approaches to identify efficacious drug…”
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Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake by Haskins, Jonathan W, Zhang, Shannon, Means, Robert E, Kelleher, Joanne K, Cline, Gary W, Canfrán-Duque, Alberto, Suárez, Yajaira, Stern, David F

“…Cholesterol is a lipid that is critical for steroid hormone production and the integrity of cellular membranes, and, as such, it is essential for cell growth…”
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Overexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis by Wali, Vikram B, Gilmore-Hebert, Maureen, Mamillapalli, Ramanaiah, Haskins, Jonathan W, Kurppa, Kari J, Elenius, Klaus, Booth, Carmen J, Stern, David F

“…Human Epidermal Growth Factor Receptor (ERBB4/HER4) belongs to the Epidermal Growth Factor receptor/ERBB family of receptor tyrosine kinases. While ERBB1,…”
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Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells by Wali, Vikram B, Haskins, Jonathan W, Gilmore-Hebert, Maureen, Platt, James T, Liu, Zongzhi, Stern, David F

“…Associations of ErbB4 (ERBB4/HER4), the fourth member of the EGFR family, with cancer are variable, possibly as a result of structural diversity of this…”
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Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration by Haskins, Jonathan W, Nguyen, Don X, Stern, David F

“…The receptor tyrosine kinase ERBB4, a member of the epidermal growth factor receptor (EGFR) family, is unusual in that ERBB4 can undergo intramembrane…”
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Seasonal variation and correlation between corticosterone and the antioxidant uric acid during stress in the Northern Cardinal (Cardinalis cardinalis) by Haskins, Jonathan W., Spizzoucco, Frank A., Walker, Brian G.

“…Glucocorticoids modify metabolism and other physiological processes in order to mount an appropriate response to stress. This stress response is affected by a…”
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EGF Receptor activates MET through MAP kinases to enhance non-small cell lung carcinoma invasion and brain metastasis by Breindel, Jerrica L., Haskins, Jonathan W., Cowell, Elizabeth P., Zhao, Minghui, Nguyen, Don X., Stern, David F.

“…MET amplification as a mechanism of acquired resistance to EGFR targeted therapies in non-small cell lung carcinoma (NSCLC) led to investigation of novel…”
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